Dodex

Anemia, Pernicious, Convalescence, Folic Acid Deficiency + 28 more

Treatment

18 FDA approvals

20 Active Studies for Dodex

Treatment for

Anemia, Pernicious

What is Dodex

Cyanocobalamin

The Generic name of this drug

Treatment Summary

Cyanocobalamin (known as Vitamin B12) is an important vitamin found in bacteria. It helps the body create DNA, and gives cells energy. Vitamin B12 exists in many forms, including cyano, methyl, deoxyadenosyl, and hydroxy cobalamin. Cyanocobalamin is the most widely used form and is available in tablet, injection, and nasal spray forms. Vitamin B12 was approved by the FDA in 1942.

O-Cal FA multivitamin

is the brand name

Dodex Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

O-Cal FA multivitamin

Cyanocobalamin

1970

Approved as Treatment by the FDA

Cyanocobalamin, also known as O-Cal FA multivitamin, is approved by the FDA for 18 uses like Pancreatic Neoplasms and Anemia, Pernicious .

Pancreatic Neoplasms

Anemia, Pernicious

Gastrointestinal Problems

folic acid

prophylaxis of Vitamin B12 deficiency

Vitamin B12 Deficiency

Gastrointestinal Surgery

Gastrointestinal Dysfunction

Neoplasms, Pancreatic

Malignant Neoplasm of Colon

Small Intestinal Bacterial Overgrowth Syndrome (SIBO)

Gluten-Sensitive Enteropathy

Total or Partial Gastrectomy

Cestode Infections

Vitamin B 12 Deficiency

Celiac Disease

Colon Cancer

Anemia, Pernicious

Effectiveness

How Dodex Affects Patients

Cyanocobalamin helps to treat vitamin B12 deficiency. It helps with growth, cell reproduction, making red blood cells and proteins, as well as breaking down fats and carbohydrates. Vitamin B12 is especially important for cells that divide quickly, like those in the bone marrow and digestive system. When given through a needle, cyanocobalamin can quickly reverse the anemia and other symptoms of vitamin B12 deficiency. Taking it through a nasal spray can also help keep the vitamin B12 levels in the body in the right range.

How Dodex works in the body

Vitamin B12 helps the body in many ways. It works with enzymes to create DNA, break down fat and protein, and convert certain molecules. It also helps make methionine, which is needed for many bodily processes like creating hormones and other substances. Without enough vitamin B12, the body cannot make enough methionine, so folate can't be regenerated. This can lead to a folate deficiency and anemia. Vitamin B12 helps incorporate folate into growing red blood cells, so a lack of it can lead to anemia.

When to interrupt dosage

The recommended dose of Dodex is contingent upon the discovered condition, such as Gastrointestinal Dysfunction, Vitamin B 12 Deficiency and Nutritional supplementation. The amount of dosage is dependent on the method of administration outlined in the table below.

Condition

Dosage

Administration

Malignant Neoplasms

, 0.025 mg, 0.012 mg, 1.0 mg/mL, 0.005 mg, 2.0 mg, 0.01 mg, 0.00405 mg/mL, 1.0 mg, 0.5 mg, 0.05 mg, 0.015 mg, 0.006 mg, 25.0 mg, 10.0 mg, 0.12 mg, 0.1 mg, 0.25 mg, 0.004 mg, 0.024 mg, 0.0225 mg, 0.035 mg, 0.002 mg, 0.001 mg, 0.125 mg, 0.0333 mg, 0.008 mg, 0.003 mg, 0.3 mg, 0.0045 mg, 0.075 mg, 0.0007 mg, 0.0125 mg, 0.02 mg, 0.027 mg, 0.033 mg, 0.016 mg, 0.00375 mg, 1.2 mg, 0.002 mg/mL, 0.017 mg, 0.115 mg, 0.013 mg, 125.0 mg, 0.0667 mg/mL, 2.5 mg, 6.0 mg, 1.5 mg, 3.0 mg, 0.000133 mg/mL, 0.2 mg, 5.0 mg, 5.0 mg/mL, 3.0 mg/mL, 0.005 mg/mg, 0.6 mg, 0.4 mg, 1.3 mg, 0.014 mg, 0.0025 mg, 0.0023 mg, 0.0168 mg, 0.009 mg, 0.00667 mg, 0.001 mg/mL, 0.06 mg, 0.0005 mg/mL, 12.0 mg, 0.003 mg/mL, 12.0 [iU], 0.03 mg, 0.005 mg/mL, 0.0009 mg/mL, 0.0002 mg/mL, 0.25 mg/mL, 0.00733 mg, 0.0002 mg, 0.00175 mg, 0.03333 mg, 0.055 mg, 0.00024 mg, 0.15 mg, 0.0166 mg, 0.052 mg, 0.08334 mg, 0.00076 mg, 0.00167 mg, 0.00625 mg, 0.00833 mg, 0.045 mg, 0.065 mg, 0.0035 mg, 0.0375 mg, 1.05 mg, 0.06666 mg, 0.018 mg, 0.04 mg, 0.00054 mg, 0.0012 mg, 0.07 mg, 0.05 mg/mg, 0.01667 mg, 0.2666 mg, 0.007 mg, 0.06667 mg, 5.0 mg/mg, 0.000075 mg, 0.1 mg/mL, 52.0 mg, 0.0014 mg, 0.0045 mg/mL, 0.0000018 mg/mg, 0.000007 mg/mL, 0.0025 mg/mL, 0.0014 mg/mL, 0.00045 mg/mL, 0.004 mg/mL, 0.00003 mg/mL, 0.00002 mg/mL, 0.01 mg/mL, 0.0000364 mg/mg, 0.00007 mg/mL, 0.0006 mg/mL, 0.00000008 mg/mg, 0.0001 mg/mL, 0.0052 mg/mL, 0.00000021 mg/mg, 0.000006 mg/mg, 0.05 mg/mL, 0.0000003 mg/mg, 0.006 mg/mL, 0.0000006 mg/mg, 0.000000024 mg/mg, 0.00011 mg/mL, 0.0033 mg/mL, 0.00012 mg/mg, 0.0004 mg/mL, 0.00017 mg/mL, 0.000002 mg/mg, 0.0000007 mg/mg, 0.0011 mg/mL, 0.00005 mg/mL, 0.0003 mg/mL, 0.0000002 mg/mg, 0.000005 mg/mg, 0.000311 mg/mL, 0.5 mg/mL

Tablet - Oral, Oral, Tablet, , Tablet, film coated - Oral, Tablet, film coated, Tablet, coated, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Capsule - Oral, Capsule, Capsule, gelatin coated - Oral, Capsule, gelatin coated, Liquid, Liquid - Oral, Nasal, Spray, Spray - Nasal, Injection, solution - Intramuscular; Subcutaneous, Injection - Intramuscular; Subcutaneous, Injection, Kit - Intramuscular; Subcutaneous, Kit, Lozenge - Oral, Tablet, coated - Oral, Liquid - Intramuscular; Subcutaneous, Solution - Intramuscular; Subcutaneous, Solution, Tablet, extended release - Oral, Tablet, extended release, Intramuscular; Intravenous; Subcutaneous, Powder - Oral, Powder, Liquid; Tablet, Solution / drops, Solution / drops - Oral, Intramuscular; Subcutaneous, Capsule, liquid filled - Oral, Capsule, liquid filled, Liquid - Intramuscular, Syrup - Oral, Syrup, Lozenge, Liquid - Intramuscular; Intravenous; Subcutaneous, Liquid; Tablet - Oral, Tablet, chewable, Tablet, chewable - Oral, Injection, powder, lyophilized, for solution - Intravenous, Liquid - Intravenous, Capsule, extended release - Oral, Solution - Oral, Capsule, extended release, Intravenous, Injection, solution - Intravenous, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Parenteral, Tablet, Delayed Release - Oral, Sublingual, Tablet - Sublingual, Gel - Nasal, Elixir - Oral, Elixir, Tablet, effervescent - Oral, Tablet, effervescent, Tablet, Delayed Release, Solution - Parenteral, Kit - Oral, Injection, powder, lyophilized, for solution, Wafer, Wafer - Oral, Intramuscular; Subcutaneous; Topical, Kit - Intramuscular; Subcutaneous; Topical, Spray, metered - Nasal, Liquid - Intramuscular; Intravenous, Spray, metered, Intramuscular; Intravenous, Capsule; Liquid - Oral, Capsule; Liquid, Solution - Intravenous, Patch, Transdermal, Capsule, coated - Oral, Injection - Intramuscular, Patch - Transdermal, Capsule, coated, Strip - Oral, Strip, Tablet, delayed release - Oral, Tablet, delayed release, Lotion - Topical, Topical, Lotion, Intramuscular; Topical, Injection - Intravenous, Powder, for solution, Powder, for solution - Oral

Total or Partial Gastrectomy

Convalescence

Folic Acid Deficiency

Beriberi

Vitamin B 12 Deficiency

Neuritis

folic acid

prophylaxis of Vitamin B12 deficiency

Gastrointestinal Dysfunction

Iron Deficiency Anemia

Diabetic Neuropathy

Gastrointestinal Problems

Avitaminosis

Vitamin B 12 Deficiency

Colon Cancer

Nervous system structure

Beriberi

Celiac Disease

Vitamin supplementation

Warnings

Dodex has two contraindications and should not be administered while encountering any of the conditions mentioned in the given table.

Dodex Contraindications

Condition

Risk Level

Notes

cobalt

Do Not Combine

Congestive Heart Failure

Do Not Combine

There are 20 known major drug interactions with Dodex.

Common Dodex Drug Interactions

Drug Name

Risk Level

Description

Abacavir

Minor

Cyanocobalamin may decrease the excretion rate of Abacavir which could result in a higher serum level.

Aclidinium

Minor

Cyanocobalamin may decrease the excretion rate of Aclidinium which could result in a higher serum level.

Acrivastine

Minor

Cyanocobalamin may decrease the excretion rate of Acrivastine which could result in a higher serum level.

Albutrepenonacog alfa

Minor

Cyanocobalamin may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.

Allopurinol

Minor

Cyanocobalamin may decrease the excretion rate of Allopurinol which could result in a higher serum level.

Dodex Toxicity & Overdose Risk

Vitamin B12 is usually not toxic, even when taken in high doses. Mild side effects such as diarrhea, itching, and skin rashes may occur. Long-term studies have not shown any links between vitamin B12 and cancer. Taking the recommended amount of vitamin B12 during pregnancy and breastfeeding is generally safe. However, it is not known if nasal sprays are safe for pregnant women, so it should only be used if necessary.

Dodex Novel Uses: Which Conditions Have a Clinical Trial Featuring Dodex?

42 active trials are presently investigating the potential of Dodex to reduce Tapeworm infestation, correct folic acid and Vitamin deficiencies.

Condition

Clinical Trials

Trial Phases

Iron Deficiency Anemia

21 Actively Recruiting

Phase 3, Not Applicable, Phase 2, Phase 1, Phase 4

Colon Cancer

50 Actively Recruiting

Not Applicable, Phase 1, Phase 2

Folic Acid Deficiency

0 Actively Recruiting

Gastrointestinal Surgery

1 Actively Recruiting

Not Applicable

Vitamin B 12 Deficiency

0 Actively Recruiting

Anemia, Pernicious

0 Actively Recruiting

Vitamin B 6 Deficiency

0 Actively Recruiting

Malignant Neoplasms

0 Actively Recruiting

Vitamin supplementation

0 Actively Recruiting

Vitamin B 12 Deficiency

0 Actively Recruiting

Vitamin B 12 Deficiency

0 Actively Recruiting

Convalescence

0 Actively Recruiting

Gastrointestinal Problems

0 Actively Recruiting

vitamin B12

0 Actively Recruiting

Nutritional supplementation

1 Actively Recruiting

Early Phase 1

Pancreatic Neoplasms

7 Actively Recruiting

Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3

Celiac Disease

0 Actively Recruiting

folic acid

0 Actively Recruiting

Small Intestinal Bacterial Overgrowth Syndrome (SIBO)

3 Actively Recruiting

Phase 1, Not Applicable

Nervous system structure

0 Actively Recruiting

Patient Q&A Section about dodex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is cyanocobalamin used for?

"Cyanocobalamin is used to treat and prevent vitamin B12 deficiency anaemia. Your body requires vitamin B12 to make red blood cells, but sometimes there may not be enough vitamins in what you eat."

Answered by AI

What is the generic name for vitamin B12?

"Different brands of cyanocobalamin include Vitamin B12, Nascobal, Athlete, Calomist, Cobalamin, Cobex, Crystamine, Prime, Rubramine PC, Vibisone, and Eligen B12."

Answered by AI

What can a B12 deficiency cause?

"The text lists symptoms which may be caused by a deficiency in vitamin B12. These symptoms include weakness, tiredness, lightheadedness, heart palpitations, shortness of breath, pale skin, a smooth tongue, constipation, diarrhea, loss of appetite, gas, nerve problems, muscle weakness, and problems walking. Vision loss may also be a symptom of a vitamin B12 deficiency."

Answered by AI

Where to Inject cyanocobalamin?

"You may then need to receive another injection once every 2-4 weeks for the rest of your life.

The medication cyanocobalamin comes as a solution to be injected into a muscle or just under the skin. It's usually injected by a healthcare provider in an office or clinic. For the first 6-7 days of treatment, you'll likely receive an injection once a day. After that, you may need to receive another injection once every 2-4 weeks for the rest of your life."

Answered by AI