What is Fansidar
PyrimethamineThe Generic name of this drug
Treatment SummaryPyrimethamine is a medication used to treat malaria and toxoplasmosis. It works by blocking the action of folic acid, which is necessary for the growth of certain parasites. Pyrimethamine is typically used in combination with a sulfonamide to treat toxoplasmosis.
Daraprimis the brand name
Fansidar Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Daraprim
Pyrimethamine
1953
13
Approved as Treatment by the FDA
Pyrimethamine, otherwise known as Daraprim, is approved by the FDA for 1 uses which include Toxoplasmosis .Toxoplasmosis
Used to treat Toxoplasmosis in combination with null
Effectiveness
How Fansidar Affects PatientsPyrimethamine is an antiparasitic drug used to treat malaria. It works by blocking the growth of malaria parasites and Toxoplasma gondii, a type of parasite that uses folic acid. It can destroy the parasites that cause malaria, but does not kill the gametocytes, or the cells that help the parasite spread to other people. When taken with other drugs, such as sulfonamides, it becomes more effective.
How Fansidar works in the bodyPyrimethamine stops the growth of malaria-causing parasites by blocking their ability to make DNA. By doing so, it prevents the parasites from multiplying and invading more cells in the body.
When to interrupt dosage
The proposed dosage of Fansidar relies upon the diagnosed state. The measure of dosage is contingent upon the method of administration specified in the table beneath.Condition
Dosage
Administration
Toxoplasmosis
, 50.0 mg, 25.0 mg, 12.5 mg
, Capsule, Tablet - Oral, Capsule - Oral, Oral, Tablet
Warnings
There are 20 known major drug interactions with Fansidar.Common Fansidar Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The excretion of Abemaciclib can be decreased when combined with Pyrimethamine.
Acepromazine
Major
The risk or severity of QTc prolongation can be increased when Pyrimethamine is combined with Acepromazine.
Aceprometazine
Major
The risk or severity of QTc prolongation can be increased when Pyrimethamine is combined with Aceprometazine.
Acetophenazine
Major
The risk or severity of QTc prolongation can be increased when Pyrimethamine is combined with Acetophenazine.
Alimemazine
Major
The risk or severity of QTc prolongation can be increased when Pyrimethamine is combined with Alimemazine.
Fansidar Novel Uses: Which Conditions Have a Clinical Trial Featuring Fansidar?
A single clinical trial is in progress to assess the capacity of Fansidar to mitigate Toxoplasmosis.Condition
Clinical Trials
Trial Phases
Toxoplasmosis
1 Actively Recruiting
Phase 4
Fansidar Reviews: What are patients saying about Fansidar?
5Patient Review
5/22/2010 I unfortunately had a negative reaction to this drug and broke out in a rash a few days after taking it. My face was swollen and I had tiny bumps and intense itching on my face and torso for several days.
2.7Patient Review
4/14/20081Patient Review
11/13/2009 My partner died after only three weeks of taking this medication. He developed TEN (toxic epidermal necrolysis) and his doctor failed to take him off the drug even after he reported a skin rash. Do not use this medication.
Patient Q&A Section about fansidar
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Who should not take Fansidar?
"Fansidar should be used with caution in patients with impaired renal or hepatic function, those with possible folate deficiency, and those with severe allergies or bronchial asthma. Some sulfonamide drugs can cause hemolysis in people with glucose-6-phosphate dehydrogenase deficiency."
Answered by AI
When should I take Fansidar?
"The first dose of Fansidar should be taken 1 or 2 days before travel to an area where the disease is present. Take the medicine during your stay and for 4 to 6 weeks after returning home."
Answered by AI
What is the drug Fansidar used for?
"Fansidar is an antiparasitic drug used to treat malaria. The active ingredients in Fansidar are sulfadoxine and pyrimethamine. Fansidar is available in generic form."
Answered by AI