Miacalcin

Hypercalcemia, Osteoporotic Fractures, Osteoporosis + 5 more
Treatment
20 Active Studies for Miacalcin

What is Miacalcin

Salmon calcitoninThe Generic name of this drug
Treatment SummaryA synthetic nasal spray made up of 32 amino acids.
Miacalcinis the brand name
Miacalcin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Miacalcin
Salmon calcitonin
1986
16

Effectiveness

How Miacalcin Affects PatientsCalcitonin stops the breakdown of bones by osteoclasts and helps build up new bone cells. This increases the overall amount of bone in the body and lowers the amount of calcium in the blood. It also helps the kidneys flush out other ions like phosphate, sodium, magnesium, and potassium, which leads to increased water, sodium, potassium, and chloride secretion in the small intestine.
How Miacalcin works in the bodyCalcitonin helps to increase bone density by binding to receptors found in osteoclasts. This binding activates enzymes that help the body absorb and retain calcium. It also triggers pathways in the body that help increase bone density.

When to interrupt dosage

The suggested dosage of Miacalcin is contingent upon the determined condition, such as Osteoporosis, Postmenopause and Hypercalcemia. The measurement of dosage shifts, in accordance with the technique of delivery (e.g. Injection, solution or Intramuscular; Subcutaneous) as highlighted in the table below.
Condition
Dosage
Administration
Immobilization
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Postmenopause
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Paget’s Disease
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Hypercalcemia
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Osteoporotic Fractures
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Osteoporosis
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Osteitis Deformans
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous
Therapeutic procedure
, 200.0 [iU], 2200.0 [iU]/mL, 20000.0 [iU]/mL, 200.0 [iU]/mL, 100.0 [iU], 200.0 [USP'U]/mL, 200.0 units/mL, 200.0 units/pump actuation, 100.0 units/mL, 200.0 units/spray
, Nasal, Spray, metered, Spray, metered - Nasal, Intramuscular, Injection, solution, Injection, solution - Intramuscular, Intramuscular; Subcutaneous, Solution, Solution - Intramuscular; Subcutaneous, Liquid, Liquid - Intramuscular; Subcutaneous, Spray - Nasal, Spray, Solution - Nasal, Liquid - Nasal, Liquid - Intramuscular; Intravenous; Subcutaneous, Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Intravenous; Subcutaneous, Injection, solution - Intramuscular; Subcutaneous

Warnings

There are 20 known major drug interactions with Miacalcin.
Common Miacalcin Drug Interactions
Drug Name
Risk Level
Description
Abacavir
Minor
Salmon calcitonin may decrease the excretion rate of Abacavir which could result in a higher serum level.
Acetaminophen
Minor
Salmon calcitonin may decrease the excretion rate of Acetaminophen which could result in a higher serum level.
Acetohexamide
Minor
The therapeutic efficacy of Acetohexamide can be decreased when used in combination with Salmon calcitonin.
Aclidinium
Minor
Salmon calcitonin may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Salmon calcitonin may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Miacalcin Toxicity & Overdose RiskSalmon calcitonin is not recommended for nursing mothers, as it has been linked to decreased fetal weight in animals. It is important to weigh the pros and cons when administering salmon calcitonin to pregnant women. In addition, salmon calcitonin can cause allergic reactions, including swelling of the tongue or throat, and an increased risk in malignancies. Other side effects include nausea, rhinitis, headaches, and back pain.
image of a doctor in a lab doing drug, clinical research

Miacalcin Novel Uses: Which Conditions Have a Clinical Trial Featuring Miacalcin?

57 active clinical trials are in progress to examine the possibility of using Miacalcin to facilitate Therapeutic procedures, Postmenopausal states and Osteitis Deformans.
Condition
Clinical Trials
Trial Phases
Hypercalcemia
1 Actively Recruiting
Phase 4
Immobilization
0 Actively Recruiting
Paget’s Disease
0 Actively Recruiting
Osteoporotic Fractures
3 Actively Recruiting
Phase 4, Not Applicable
Osteoporosis
34 Actively Recruiting
Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3
Osteitis Deformans
0 Actively Recruiting
Postmenopause
8 Actively Recruiting
Phase 2, Not Applicable, Phase 1
Therapeutic procedure
0 Actively Recruiting

Miacalcin Reviews: What are patients saying about Miacalcin?

5Patient Review
11/14/2007
Miacalcin for Decreased Bone Mass Following Menopause
I've been using Miacalcin for a while now, and it's easy to use but slow-acting. My bone density test showed that I was losing bone mass, so now I take it in combination with Boniva.
5Patient Review
2/28/2008
Miacalcin for Decreased Bone Mass Following Menopause
This medication has increased my bone density, and I've been using it for a while now without any issues.
5Patient Review
6/18/2010
Miacalcin for Decreased Bone Mass Following Menopause
Miacalcin was working great for me, but since my insurance company raised the price beyond what I can afford, I've experienced a significant amount of bone loss.
5Patient Review
6/22/2009
Miacalcin for Decreased Bone Mass Following Menopause
Miacalcin not only improved the results on my spine, but has kept my readings from my hip bone stable for the past three years.
4.7Patient Review
4/4/2009
Miacalcin for Decreased Bone Mass Following Menopause
I had no issues taking this medication, and it didn't come with any unwanted side effects. However, after a year of use my bone density test did not show any improvement.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about miacalcin

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Miacalcin made from salmon?

"Miacalcin is a hormone that is found naturally in the thyroid gland. It is used to treat Paget's disease of bone, postmenopausal osteoporosis, or high levels of calcium in the blood (hypercalcemia)."

Answered by AI

Is Miacalcin effective with osteoporosis?

"Miacalcin injection can help treat osteoporosis in postmenopausal women who are more than 5 years past menopause. The evidence that it works comes from trials where people taking the injection had increases in the amount of calcium in their bodies. However, it has not been shown to help reduce fractures."

Answered by AI

What kind of drug is Miacalcin?

"Calcitonin is a medication that comes in the form of a nasal spray or injection. It is used to treat osteoporosis in postmenopausal females, Paget's disease of bone, and high calcium. Although it is available in a generic form, it is not typically the first choice for treatment."

Answered by AI

What is Miacalcin used for?

"This medication is used to treat certain bone problems, such as Paget's disease, postmenopausal osteoporosis, by reducing high blood levels of calcium. Calcitonin, a man-made hormone, works by slowing bone loss and maintaining normal calcium levels in the blood."

Answered by AI

Clinical Trials for Miacalcin

Have you considered Miacalcin clinical trials? We made a collection of clinical trials featuring Miacalcin, we think they might fit your search criteria.
Have you considered Miacalcin clinical trials? We made a collection of clinical trials featuring Miacalcin, we think they might fit your search criteria.
Have you considered Miacalcin clinical trials? We made a collection of clinical trials featuring Miacalcin, we think they might fit your search criteria.
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