This trial is evaluating whether Aerobic Training will improve 1 primary outcome and 5 secondary outcomes in patients with Breast Cancer. Measurement will happen over the course of at baseline, mid-point (12 weeks approximately) , and follow-up (24 weeks approximately) testing.
This trial requires 144 total participants across 4 different treatment groups
This trial involves 4 different treatments. Aerobic Training is the primary treatment being studied. Participants will be divided into 4 treatment groups. There is no placebo group. The treatments being tested are not being studied for commercial purposes.
Findings from a recent study suggest that while breast cancer has a cure rate of 30-50%, a substantial proportion of patients will still have some disease at the time of their deaths. Findings from a recent study of the current study may have important implications on the future use of chemotherapy in breast cancer treatment.
Breast cancer, the leading cause of cancer related deaths among women and women’s most common cancer, occurs in both sexes. It can occur in any region of the breast, can be detected during an exam, and may be felt through a finger poke test. Breast cancer is more common in postmenopausal women who have not had a baby. In most cases, breast cancer is not a single form. Breast cancer is a disease that varies from one person to the next. Treatment depends on what type of cancer the person is diagnosed with and how advanced the disease is and the person's general health. The five-year survival rate was greater than 99% and decreased steadily from 1996 to 2015.
The American Cancer Society estimates that 1,095,600 new cases of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) will be diagnosed in 2020, making it the second most prevalent cancer in men.
Treatment for [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) depends on the stage of the disease, the type of cancer, and how aggressive it is. Breast cancers may receive surgery (biopsies of the lump(s)), radiation, chemotherapy, hormonal therapy, targeted therapy, or a combination. Most tumors respond well to surgery and treatment with adjuvant radiation, medication, or other therapy. Surgical removal of tumors from the local lymph nodes is needed to get cancer in all stage 4 to stage 6 breast cancer patients. A biopsy of the lump and/or a tissue sample is also done to rule out any other cancer that may be present inside the breast.
Signs of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) can include a lump or lumpiness in the breast due to cancer. The lump may be warm or tender to the touch. Signs can also include pain or bleeding in the breast or nipple. A hard breast can feel like a stone or bump. Other signs include the following: nipple discharge or nipple irritation or redness, skin changes, nipple swelling, and changes in the size or shape of the breast. Many women only learn of their cancer or that they have it after the tumor is advanced. The diagnosis of cancer in a postmenopausal woman is made because the symptoms last beyond two years after the menopause or the body starts producing less estrogen. The symptoms can be confused with other health conditions.
Even though both men and women can develop breast cancer, it appears that the vast majority of breast cancers are found in women over 40 years.
We found that aerobic training can be used as a therapeutic modality for the reduction of blood pressure and glucose, and as adjuvant therapy for the control of other health risks associated with obesity (increased body fat percentage and risk factors in the cardiovascular risk factor (CVRF) concept). In this way, aerobic training is useful for the management of CVRF and its associated diseases.
These data are important for the design and interpretation of large clinical studies in which the incidence of breast cancer is the outcome of interest.
The seriousness of [breast cancer](https://www.withpower.com/clinical-trials/breast-cancer) can't be underestimated. The risk is far higher in case the cancer is in early stages. The higher the stage of cancer, the lower the probability of a full recovery from the disease. In case of late stage or metastatic breast cancer, the patient is unlikely to achieve a full resolution of the disease. When a cancer with metastatic stage is diagnosed, only a few days are left. In these cases, the overall average survival from cancer is approximately 2 months. However, in case of a late stage cancer, the survival rate rises to approximately 6 months. The treatment in case of metastatic cancer is to focus on suppressing metastasis through different methods.
In India, only 2 out of 3 women are diagnosed with early stage breast cancer which is important for improving the survival rate because it is a key factor in predicting survival for patients. Survival rate for metastatic breast cancer is still poor, even though there is significant improvement in the management in recent years. Survival rate for small cell types of non-metastatic breast cancer is poor except in the cases of hormone naïve breast cancer.
Data from a recent study shows that aerobic training does not have beneficial effects in the treatment of breast cancer, as other studies have found. Further studies are required to determine whether alternative training systems would have a more favourable outcome and would therefore be preferable for breast cancer patients.