Diet and Exercise Intervention for Breast Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
The proposed study is a randomized trial evaluating the impact of a dietary and physical activity guidelines intervention vs. usual care on adherence to breast cancer treatments, body composition, and changes in biomarkers in 172 women newly diagnosed with breast cancer scheduled to receive neoadjuvant or adjuvant chemotherapy.
Do I have to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
Is the diet and exercise intervention safe for breast cancer patients?
How does the Dietary/Physical Activity intervention treatment differ from other treatments for breast cancer?
This treatment is unique because it focuses on lifestyle changes, specifically a low-calorie diet and regular physical activity, to promote weight loss and improve health outcomes in breast cancer survivors, rather than using medication or surgery. It aims to improve prognosis by addressing obesity, a known negative factor in breast cancer survival, through sustainable lifestyle modifications.16789
What data supports the effectiveness of the treatment Dietary/Physical Activity intervention for breast cancer?
Who Is on the Research Team?
Tara Sanft, M.D.
Principal Investigator
Yale University
Melinda Irwin, Ph.D.
Principal Investigator
Yale University
Are You a Good Fit for This Trial?
This trial is for English-speaking women recently diagnosed with Stage I-III breast cancer who are about to start chemotherapy. They must be able to walk and follow the study's guidelines. Women can't join if they're pregnant, planning pregnancy, have had a stroke or heart failure in the past year, already follow similar health guidelines, or have completed their second chemo session.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive neoadjuvant or adjuvant chemotherapy along with dietary and physical activity intervention
Follow-up
Participants are monitored for adherence to treatment, changes in biomarkers, body composition, diet, physical activity, and quality of life
Long-term Follow-up
Assessment of long-term outcomes such as quality of life and physical activity
What Are the Treatments Tested in This Trial?
Interventions
- Dietary/Physical Activity intervention
- Usual Care
Find a Clinic Near You
Who Is Running the Clinical Trial?
Yale University
Lead Sponsor
National Cancer Institute (NCI)
Collaborator