200 Participants Needed

NAC for COVID-19

(NACinCOVID2 Trial)

ML
TS
Overseen ByTom Seufert, MD
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Cambridge Health Alliance
Prior Safety DataThis treatment has passed at least one previous human trial
Approved in 2 JurisdictionsThis treatment is already approved in other countries

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial is testing if taking an NAC supplement can make COVID-19 symptoms less severe and shorter in adults who have tested positive but are not hospitalized.

Are You a Good Fit for This Trial?

This trial is for individuals who have tested positive for COVID-19 within the past 7 days. It's not suitable for pregnant women or those already hospitalized due to COVID.

Inclusion Criteria

Positive COVID test <= 7 days of enrollment

Exclusion Criteria

Pregnant
Already hospitalized due to COVID

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

1-2 weeks

Treatment

Participants receive NAC or placebo for 14 days

2 weeks
Daily online symptom-tracker for 3 weeks

Follow-up

Participants are monitored for symptom severity and duration, and need for hospitalization

24 weeks
Weekly online symptom-tracker for 3 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • N-acetylcysteine
  • Placebo
Trial Overview The study aims to see if taking N-acetylcysteine (NAC) orally can reduce the severity and length of COVID-19 symptoms compared to a placebo, which has no active ingredients.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Placebo Group
Group I: NACExperimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

N-acetylcysteine is already approved in United States, European Union for the following indications:

🇺🇸
Approved in United States as N-acetylcysteine for:
🇪🇺
Approved in European Union as N-acetylcysteine for:

Find a Clinic Near You

Who Is Running the Clinical Trial?

Cambridge Health Alliance

Lead Sponsor

Trials
65
Recruited
22,400+

Alturix

Collaborator

Trials
1
Recruited
200+

The Thoracic Foundation

Collaborator

Trials
1
Recruited
200+
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