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Behavioral Intervention

Exercise Program for Prostate Cancer

Q: Are there still vacancies for patients in this medical experiment?

<p>Unfortunately, this clinical trial is not currently accepting new participants. Initially posted on November 1st 2023 and last edited on September 13th 2023, it has stopped recruiting for the time being. Nevertheless, there are over 1500 other medical studies that are still actively seeking patients.</p>

N/A

Recruiting

Led By Christina Dieli-Conwright, MD

Research Sponsored by Dana-Farber Cancer Institute

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Diagnosed with metastatic prostate cancer

Aged ≥18 years; due to the rarity of the disease in those <18 years, this age bracket will not be included

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline (week 0) and post-intervention (week 17)

Awards & highlights

Study Summary

This trial is to find if it can help prostate cancer patients improve their frailty and sarcopenic status through a 16-week exercise program.

Who is the study for?

The FIERCE Trial is for English-speaking men over 18 with metastatic prostate cancer who are pre-frail or frail and on ADT. They must be willing to travel to Dana-Farber Cancer Institute, have physician clearance for exercise, and not already doing much structured exercise.Check my eligibility

What is being tested?

This study tests a 16-week supervised circuit training program combining resistance and functional exercises with self-directed aerobic activity. It aims to see if this can improve frailty, sarcopenia (muscle loss), and disease progression in patients.See study design

What are the potential side effects?

While the trial itself doesn't involve medication that would cause side effects, exercising may lead to muscle soreness, fatigue, or injury especially if participants are not used to physical activity.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have been diagnosed with prostate cancer that has spread.

Select...

I am 18 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline (week 0) and post-intervention (week 17)

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline (week 0) and post-intervention (week 17)

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline (week 0) and post-intervention (week 17) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Circulating Inflammation for Exercise Group

Frailty

Secondary outcome measures

Sarcopenia

Skeletal Muscle Biomarkers - myokines

Trial Design

2Treatment groups

Experimental Treatment

Group I: Exercise GroupExperimental Treatment1 Intervention

Participants will partake in a 16-week supervised exercise program.

Group II: Attention Control GroupExperimental Treatment1 Intervention

Participants will continue with their normal daily activities.

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Dana-Farber Cancer InstituteLead Sponsor

1,079 Previous Clinical Trials

340,900 Total Patients Enrolled

77 Trials studying Prostate Cancer

16,105 Patients Enrolled for Prostate Cancer

Prostate Cancer FoundationOTHER

47 Previous Clinical Trials

2,700 Total Patients Enrolled

28 Trials studying Prostate Cancer

1,930 Patients Enrolled for Prostate Cancer

Christina Dieli-Conwright, MDPrincipal InvestigatorDana-Farber Cancer Institute

1 Previous Clinical Trials

30 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still vacancies for patients in this medical experiment?

"Unfortunately, this clinical trial is not currently accepting new participants. Initially posted on November 1st 2023 and last edited on September 13th 2023, it has stopped recruiting for the time being. Nevertheless, there are over 1500 other medical studies that are still actively seeking patients."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

Christina Dieli-Conwright, PhD 2024. "Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06040125.

All > Sarcopenia > Metastatic Prostate Cancer