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Neuromodulation

Neuromodulation + Cognitive Training for Substance Use Disorders

N/A

Recruiting

Led By Kelvin Lim, MD

Research Sponsored by University of Minnesota

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 2 months

Awards & highlights

Study Summary

This trial is testing a new intervention to help people with substance use disorder by targeting brain biomarkers that make relapse more likely.

Who is the study for?

This trial is for individuals aged 18-65 with substance use disorders (SUD) or alcohol use disorder (AUD), who have been abstinent for at least 3 weeks but not more than 9 months. Participants must intend to stay in their treatment program and meet specific diagnostic criteria, excluding those with neurological conditions, severe head injuries, recent neuromodulation treatments, or under court-mandated rehab.Check my eligibility

What is being tested?

The study tests tDCS-Augmented Cognitive Training aimed at improving cognition and treatment outcomes for SUD/AUD. It targets brain biomarkers associated with relapse vulnerability by combining transcranial direct current stimulation (tDCS) with cognitive exercises.See study design

What are the potential side effects?

Potential side effects of tDCS may include mild discomfort or itching under the electrode during application, headache, fatigue, nausea, and insomnia. Cognitive training typically does not cause side effects but can sometimes lead to mental fatigue.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 2 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~2 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Percent of participants with clean drug screens

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Active tDCSExperimental Treatment2 Interventions

Group II: Sham tDCSPlacebo Group1 Intervention

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

tDCS

2017

Completed Phase 2

~640

Cognitive Training

2008

Completed Phase 3

~4100

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of MinnesotaLead Sponsor

1,380 Previous Clinical Trials

1,588,662 Total Patients Enrolled

9 Trials studying Alcoholism

2,045 Patients Enrolled for Alcoholism

Kelvin Lim, MDPrincipal InvestigatorUniversity of Minnesota

3 Previous Clinical Trials

174 Total Patients Enrolled

Media Library

tDCS-Augmented Cognitive Training (Neuromodulation) Clinical Trial Eligibility Overview. Trial Name: NCT04426214 — N/A

Alcoholism Research Study Groups: Sham tDCS, Active tDCS

Alcoholism Clinical Trial 2023: tDCS-Augmented Cognitive Training Highlights & Side Effects. Trial Name: NCT04426214 — N/A

tDCS-Augmented Cognitive Training (Neuromodulation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04426214 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any remaining vacancies to join this research protocol?

"Clinicaltrials.gov confirms that this clinical trial, initially posted on July 16th 2021 and last edited a year later, is currently recruiting patients."

Answered by AI

What is the maximum enrollment cap for this research project?

"Affirmative. Clinicaltrial.gov says that this clinical trial is currently enrolling patients, with the initial post date being July 16th 2021 and a recent update on July 15th 2022. This research requires 80 participants from one medical centre to take part in testing."

Answered by AI

Is there an age limitation on enrollment in this clinical experiment?

"In accordance to the eligibility requirements of this medical trial, individuals need to be 18 or older but no more than 65."

Answered by AI

Who is the ideal participant for this medical research project?

"This trial seeks 80 individuals, aged 18-65 years old, who have been diagnosed with an Alcohol Use Disorder. In order to participate in this study they must be willing to remain engaged until the end of the intervention period and abstain from all substances (aside from nicotine or caffeine) for a minimum of 3 weeks at enrollment. Additionally, candidates are required to provide written consent and adhere to all protocols."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Neuromodulation and Cognitive Training for Substance Use Disorders

2021. "Neuromodulation and Cognitive Training for Substance Use Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04426214.

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