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Anti-fibrinolytic

Rapid-rate administration of TXA for Healthy Subjects (RateTXA Trial)

Phase 4

Recruiting

Led By Anton Chau, MD MMSc

Research Sponsored by University of British Columbia

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 15 minutes starting from the time of completed txa administration.

Awards & highlights

RateTXA Trial Summary

"This trial is looking at how quickly tranexamic acid is given to pregnant women undergoing cesarean delivery and how it affects their blood pressure changes over 1 minute compared to 10 minutes."

Who is the study for?

This trial is for healthy pregnant women scheduled for cesarean delivery. Specific eligibility details are not provided, but typically participants would need to meet certain health standards and have no conditions that could interfere with the study.Check my eligibility

What is being tested?

The study is testing how different rates of administering Tranexamic Acid (TXA) affect blood pressure in patients. It compares the effects when TXA is given over 1 minute versus over 10 minutes during a cesarean delivery.See study design

What are the potential side effects?

While specific side effects are not listed, common ones associated with Tranexamic Acid can include nausea, vomiting, diarrhea, and possible allergic reactions or changes in blood pressure.

RateTXA Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 15 minutes starting from the time of completed txa administration.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~15 minutes starting from the time of completed txa administration.

This trial's timeline: 3 weeks for screening, Varies for treatment, and 15 minutes starting from the time of completed txa administration. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in systolic blood pressure from baseline over 15 minutes post-TXA administration between groups.

Secondary outcome measures

Incidence of central nervous system side effects

Incidence of hypertension

Incidence of hypotension

+2 more

RateTXA Trial Design

2Treatment groups

Active Control

Group I: Rapid-rate administration of TXAActive Control1 Intervention

This group will be administered tranexamic acid over 1 minute

Group II: Slow-rate administration of TXAActive Control1 Intervention

This group will be administered tranexamic acid over 10 minutes

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of British ColumbiaLead Sponsor

1,419 Previous Clinical Trials

2,467,058 Total Patients Enrolled

Anton Chau, MD MMScPrincipal InvestigatorDepartment of Anesthesia BC Women's Hospital

6 Previous Clinical Trials

811 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new patients currently being accepted for enrollment in this medical study?

"Indeed, the details on clinicaltrials.gov highlight that this investigation is currently enrolling participants. The trial was initially disclosed on March 30th, 2024 and most recently revised on April 4th, 2024. The research aims to recruit a total of 110 individuals from one designated site."

Answered by AI

Has the FDA sanctioned the gradual delivery of TXA?

"Given that this treatment is sanctioned and falls under a Phase 4 trial, the Power team has assessed the safety of slow-rate administration of TXA as 3 on our scale."

Answered by AI

What is the current number of subjects enrolled in this medical study?

"Indeed, the information available on clinicaltrials.gov highlights that this trial is currently enrolling volunteers. This particular study was initially posted on March 30th, 2024, and its most recent update occurred on April 4th of the same year. The research aims to recruit a total of 110 participants from one designated site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.

Anthony Chau 2024. "Rate of Tranexamic Acid Administration on Blood Pressure (RateTXA) Study.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT06356948.