Topical Tranexamic Acid for Wrist Fractures
(TRADR Trial)
Trial Summary
What is the purpose of this trial?
The goal of this study is to find out whether the use of topical tranexamic acid (TXA) into the surgical wound will result in less post-operative pain, less pain killer use, and better post-operative use of the wrist in people undergoing surgery for a wrist fracture compared to not using topical TXA (placebo).
Will I have to stop taking my current medications?
The trial requires that you stop taking anticoagulants (blood thinners) in time for surgery, following specific guidelines. If you are currently using opioids, you cannot participate in the trial.
What data supports the effectiveness of the drug Tranexamic Acid when applied topically for wrist fractures?
How is the drug Tranexamic Acid unique for treating wrist fractures?
Eligibility Criteria
This trial is for individuals who are undergoing surgery for a wrist fracture. It aims to see if applying tranexamic acid (TXA) directly into the wound can reduce pain and improve wrist function post-surgery compared to a placebo.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive either topical tranexamic acid or placebo during wrist fracture surgery
Follow-up
Participants are monitored for pain, function, and opioid use post-surgery
Treatment Details
Interventions
- Topical Tranexamic Acid
Find a Clinic Near You
Who Is Running the Clinical Trial?
University Health Network, Toronto
Lead Sponsor