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Accelerated Surgery for Hip Fracture (HIP ATTACK-2 Trial)
N/A
Recruiting
Led By Robert Feibel, M.D
Research Sponsored by Population Health Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
diagnosis of hip fracture during working hours with a low-energy mechanism requiring surgery
age ≥45 years
Timeline
Screening 3 weeks
Treatment Varies
Follow Up within 7 days and 90 days post randomization
Awards & highlights
HIP ATTACK-2 Trial Summary
This trial will compare accelerated surgery for hip fracture in patients with acute myocardial injury to standard care, in order to determine if it is superior in reducing death.
Who is the study for?
This trial is for individuals aged 45 or older who have a hip fracture from a low-energy event and need surgery, with elevated troponin levels indicating heart muscle injury. It's not for those with certain types of severe heart attacks, on specific anticoagulants without reversal options, refusing consent, previously enrolled in the same trial, needing emergency surgeries for other reasons, or with particular fracture types.Check my eligibility
What is being tested?
The HIP ATTACK-2 trial is testing if getting surgery faster than usual for a hip fracture in patients who also have acute myocardial injury leads to better outcomes like lower death rates at 90 days post-surgery. It will also look at mobility recovery time, complications such as heart failure and stroke, delirium occurrence, pain levels and overall quality of life.See study design
What are the potential side effects?
While the study doesn't list specific side effects related to accelerated medical clearance and surgery itself beyond typical surgical risks (like infection or bleeding), it will monitor major complications including new heart attacks, congestive heart failure events and strokes.
HIP ATTACK-2 Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have a hip fracture from a low-energy incident needing surgery.
Select...
I am 45 years old or older.
HIP ATTACK-2 Trial Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ within 7 days and 90 days post randomization
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~within 7 days and 90 days post randomization
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Perinatal death
Secondary outcome measures
Ability to independently walk 3 meters
Acute Congestive Heart Failure
Composite of major complications
+7 moreOther outcome measures
Acute kidney injury
Acute renal failure resulting in dialysis
Bleeding
+16 moreHIP ATTACK-2 Trial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Accelerated medical clearance and surgeryExperimental Treatment1 Intervention
Accelerated medical clearance and targeted arrival to the operating room within 6 hours of diagnosis of a hip fracture requiring surgical repair.
Group II: Standard surgical careActive Control1 Intervention
Hip fracture repair and surgical care according to treating institution guidelines.
Find a Location
Who is running the clinical trial?
Population Health Research InstituteLead Sponsor
155 Previous Clinical Trials
678,812 Total Patients Enrolled
Canadian Institutes of Health Research (CIHR)OTHER_GOV
1,344 Previous Clinical Trials
26,452,317 Total Patients Enrolled
Robert Feibel, M.DPrincipal InvestigatorThe Ottawa Hospital
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Eligibility Criteria:
This trial includes the following eligibility criteria:- I need emergency surgery for a condition unrelated to the trial.I have a fracture around a joint replacement, an open fracture, or fractures on both sides.I have a hip fracture from a low-energy incident needing surgery.I have had a heart attack with complications like muscle rupture or shock.I am on a blood thinner that cannot be easily reversed.I am taking vitamin K for blood clots but have had a bad reaction to heparin before.I do not agree to participate in this study.I am 45 years old or older.
Research Study Groups:
This trial has the following groups:- Group 1: Accelerated medical clearance and surgery
- Group 2: Standard surgical care
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What is the current enrollment capacity for this clinical investigation?
"To fulfill the requirements of this medical trial, 1100 participants with pre-determined qualifications must be enrolled. These volunteers can join from multiple sites such as Ottawa General Hospital in Ontario and Markham Stouffville Hospital within Maryland."
Answered by AI
Is this research endeavor accepting new participants?
"Correct. According to the clinicaltrials.gov page, this medical trial is currently looking for participants; it was initially posted on November 22nd 2021 and last updated on November 18th 2022. The study requires 1100 patients from 9 different sites across the nation."
Answered by AI
How many health care centers are administering this examination in the metropolis?
"The current trial is underway at nine separate locations, with three of them being in the Canadian cities of Ottawa, Markham and Hamilton. It may be advantageous to choose a nearby clinic that minimizes any need for travel if you do partake."
Answered by AI
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