Health and Wellness Products for Cognitive Functioning

Overseen By Susan Hewlings

Age: 18+

Sex: Any

Trial Phase: Academic

Sponsor: Radicle Science

Must not be taking: Anticoagulants, Antidepressants, Antipsychotics, others

Disqualifiers: Pregnancy, Heavy drinking, Cardiac dysfunction, others

Compensation: Varies

Number of Visits: Unknown

Duration: 7 weeks

750 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests the effects of two health and wellness products on cognitive function, which includes thinking, memory, and attention. Participants will be randomly assigned to receive either Clarity Active Product 1, Clarity Active Product 2, or a placebo (a substance with no active ingredients) to compare their impact. The trial seeks individuals who believe they could achieve at least a 30% improvement in cognitive health. Participants must reside in the U.S., be willing to take a study product without knowing if it's the real thing or a placebo, and have no major recent illnesses or serious health conditions. As an unphased trial, this study offers a unique opportunity to contribute to understanding cognitive health improvements through innovative wellness products.

Will I have to stop taking my current medications?

You may need to stop taking certain medications if they interact with the study products. These include blood thinners, blood pressure meds, anxiety or depression meds, and others. It's best to discuss your specific medications with the study team.

Is there any evidence suggesting that this trial's treatments are likely to be safe?

Research has shown that both Clarity Active Product 1 and Clarity Active Product 2 underwent testing in earlier studies with adult participants. These studies were carefully designed to compare the products with a placebo, meaning some participants received a fake version instead of the real product. This design ensures accurate results.

Participants used the products as instructed for several weeks to assess their effects on cognitive function, including memory, attention, and other mental abilities. Importantly, these studies were double-blind, so neither the participants nor the researchers knew who received which treatment. This approach reduces bias and provides clearer results.

Regarding safety, these studies are part of ongoing research to evaluate user tolerance of the products. While specific safety details from these studies aren't provided here, the continuation of research suggests that the products are considered safe enough for further testing. If major safety concerns existed, the products likely wouldn't have advanced to this stage.

Overall, for those considering joining a trial with these products, it's important to know that previous participants used them under controlled conditions, and researchers are actively studying their safety and effectiveness. ^{1 2 3 4 5}

Why are researchers excited about this trial's treatments?

Researchers are excited about Clarity Active Products 1 and 2 for enhancing cognitive function because they offer a fresh approach compared to standard treatments like cognitive training or medications such as donepezil. Unlike these traditional options, which often focus on targeting neurotransmitters, Clarity Active Products may work by supporting overall brain health through unique active ingredients. These ingredients could potentially improve cognitive performance more naturally and with fewer side effects. Additionally, the products might offer a novel delivery method that enhances absorption and efficacy, making them a promising alternative for cognitive support.

What evidence suggests that this trial's treatments could be effective for cognitive functioning?

This trial will compare Clarity Active Product 1 and Clarity Active Product 2 with a placebo control to evaluate their effects on cognitive functioning. Research shows that Clarity Active Product 1 is designed to potentially improve brain function. Previous studies have used a placebo to compare its effects, revealing its true impact on brain health. Early results suggest that participants might notice improvements in mental sharpness and overall thinking abilities.

Research also supports Clarity Active Product 2 for boosting brain function. Although specific data remains limited, the product aims to improve mental clarity and slow memory loss. This trial tests both products to determine their effectiveness in maintaining brain health and function. ^{1 3 6 7 8}

Who Is on the Research Team?

Susan Hewlings

Principal Investigator

Radicle Science

Are You a Good Fit for This Trial?

This trial is for individuals interested in exploring the effects of health and wellness products on cognitive function. Specific eligibility criteria are not provided, but typically participants would be healthy adults without any major cognitive impairments.

Inclusion Criteria

Resides in the United States

Has the opportunity for at least 30% improvement in their primary health outcome

My participation will be based on my sex assigned at birth.

Exclusion Criteria

Report being pregnant, trying to become pregnant, or breastfeeding

Unable to provide a valid US shipping address and mobile phone number

Reports current enrollment in another clinical trial

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive the study product or placebo for cognitive function assessment

7 weeks

All assessments are electronic; no in-person visits

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

• Clarity Active Product 1
• Clarity Active Product 2
• Clarity Product Placebo Control

Trial Overview The study is testing two different 'Clarity' active products against a placebo to see if they improve cognitive functioning. It's a randomized, double-blind trial, meaning neither the researchers nor participants know who gets which product.

How Is the Trial Designed?

Group I: Active Product 2 Experimental Treatment 1 Intervention

Clarity Active Product 2

Group II: Active Product 1 Experimental Treatment 1 Intervention

Clarity Active Product 1

Group III: Placebo Control Placebo Group 1 Intervention

Clarity Product Placebo Control

Who Is Running the Clinical Trial?

Radicle Science

Lead Sponsor

Trials

24

Recruited

46,200+

Citations

1. clinicaltrials.gov clinicaltrials.gov/study/NCT07219641

Radicle Clarity RPN: A Study Assessing the Impact of ... Radicle Clarity RPN: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes.

2. clinicaltrials.gov clinicaltrials.gov/study/NCT05652725

Radicle Clarity: A Study of Health and Wellness Products ... This is a randomized, blinded, placebo-controlled study conducted with adult participants, age 21 and older and residing in the United States.

3. withpower.com withpower.com/trial/phase-cognitive-functioning-2-2024-d9038

Wellness Products for Cognitive Functioning Clarity Active Study Product 1.1 is unique because it is part of a clinical trial that includes a placebo control, which helps determine its specific effects ...

4. patlynk.com patlynk.com/trial/NCT07013630

Health and Wellness Products on Cognitive Function in ... This study looks at how health and wellness products might improve brain function and overall health in adults living in the United States.

5. ichgcp.net ichgcp.net/clinical-trials-registry/550763-radicle-clarity-a-study-assessing-the-impact-of-health-and-wellness-products-on-cognitive-function-and-related-health-outcomes

Clarity Cognitive Health Study: Assessing Dietary ... - ICH GCP The research team specifically seeks individuals who believe they have significant room for improvement in their cognitive function—at least 30% ...

6. clinicaltrial.be clinicaltrial.be/en/details/427849?per_page=20&only_recruiting=0&only_eligible=0&only_active=0

Radicle Clarity 24: A Study of Health and Wellness Produc... Clarity Active Study Product 1.1 Usage​​ Participants will use their Radicle Clarity Active Study Product 1.1 as directed for a period of 6 weeks.

7. withpower.com withpower.com/trial/phase-cognitive-functioning-7-2025-3cbd4

Clarity Products for Cognitive Functioning A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on cognitive function and related health outcomes.

8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC4595564/

A randomized, double-blind, placebo controlled, parallel ... The goal of this study was to investigate the efficacy of a self-described cognitive enhancing nutraceutical on cognitive functioning in a group of healthy ...