Brain Stimulation + Cognitive Behavioral Therapy for Depression
Trial Summary
What is the purpose of this trial?
The purpose of the proposed study is to examine if a repeated treatment of High Definition Transcranial Direct Current Stimulation (HD-tDCS) can increase the functional connectivity between the left ventrolateral prefrontal cortex and posterior cingulate, which may further enhance the effects of cognitive behavioral therapy with mindfulness classes.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment HD-tDCS for depression?
Research shows that transcranial direct current stimulation (tDCS), a part of HD-tDCS, can help improve symptoms of depression, especially when combined with other therapies like positive psychotherapy. Studies have found that people receiving combined treatments often experience greater mood improvements and increased hope and optimism.12345
Is brain stimulation with tDCS safe for humans?
How does the Brain Stimulation + Cognitive Behavioral Therapy treatment for depression differ from other treatments?
This treatment is unique because it combines transcranial direct current stimulation (tDCS), a non-invasive method that uses electrical currents to stimulate specific brain areas, with cognitive behavioral therapy (CBT), a type of talk therapy. This combination aims to enhance the effects of each component, potentially offering a more effective approach for those who do not respond to standard treatments like medication or CBT alone.1461112
Eligibility Criteria
This trial is for individuals in Manitoba enrolled in virtual mental health programs, such as CBT or DBT, or those who provide these services. It's not suitable for people with MRI contraindications like metallic implants or claustrophobia.Inclusion Criteria
Exclusion Criteria
Trial Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive repeated treatment of High Definition Transcranial Direct Current Stimulation (HD-tDCS) combined with cognitive behavioral therapy and mindfulness classes
Follow-up
Participants are monitored for safety and effectiveness after treatment
Treatment Details
Interventions
- HD-tDCS (Non-invasive Brain Stimulation)
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Manitoba
Lead Sponsor
Winnipeg Foundation
Collaborator