Perceptual Learning for Lazy Eye

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Nova Southeastern University College of Optometry, Fort Lauderdale, FL
Lazy Eye
Perceptual Learning - Behavioral
Eligibility
Any Age
All Sexes
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Study Summary

Amblyopia, a developmental abnormality that impairs spatial vision, is a major cause of vision loss, resulting in reduced visual acuity and reduced sensitivity to contrast. This study uses psychophysical measures to study neural plasticity in both adults and children with amblyopia.

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 2 Secondary · Reporting Duration: 9 months

9 months
Change in contrast sensitivity before and after the intervention
Change in positional (or Vernier) acuity before and after the intervention
Change in stereoacuity before and after the intervention
Change in visual acuity before and after the intervention

Trial Safety

Safety Progress

1 of 3

Trial Design

3 Treatment Groups

Occlusion therapy
1 of 3
Video Games
1 of 3
Perceptual learning
1 of 3
Active Control
Experimental Treatment

90 Total Participants · 3 Treatment Groups

Primary Treatment: Perceptual Learning · No Placebo Group · N/A

Video Games
Behavioral
Experimental Group · 1 Intervention: Video Game Vision Training · Intervention Types: Behavioral
Perceptual learning
Behavioral
Experimental Group · 1 Intervention: Perceptual Learning · Intervention Types: Behavioral
Occlusion therapy
Behavioral
ActiveComparator Group · 1 Intervention: Occlusion Therapy · Intervention Types: Behavioral

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 9 months

Trial Background

Prof. Roger W. Li, Associate Professor
Principal Investigator
Nova Southeastern University
Closest Location: Nova Southeastern University College of Optometry · Fort Lauderdale, FL
2019First Recorded Clinical Trial
0 TrialsResearching Lazy Eye
1 CompletedClinical Trials

Eligibility Criteria

Age Any Age · All Participants · 2 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
The patient has a VA difference of 0.1 logMAR or more between the two eyes.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.

References