Control for Diabetic Retinopathy

University of Illinois at Chicago, Chicago, IL
Targeting 2 different conditionsMelatonin +1 morePhase 2RecruitingResearch Sponsored by University of Illinois at Chicago

Study Summary

This trial looks at whether melatonin can help improve symptoms in patients with diabetic retinopathy.

Eligible Conditions
  • Diabetic Retinopathy
  • Diabetes


Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~24 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Melatonin and Cortisol Rhythm
Sleep pattern

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.

Trial Design

2Treatment groups
Active Control
Group I: ControlActive Control1 Intervention
Group II: MelatoninActive Control1 Intervention

Find a site

Who is running the clinical trial?

University of Illinois at ChicagoLead Sponsor
566 Previous Clinical Trials
1,554,439 Total Patients Enrolled
University of ChicagoOTHER
961 Previous Clinical Trials
791,164 Total Patients Enrolled

Media Library

Diabetic Retinopathy Research Study Groups: Control, Melatonin

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Has there been any other research done concerning the efficacy of Control?

"Currently, 24 clinical trials are in progress to research Control. Of these ongoing studies, 4 have reached Phase 3 development. While the primary location of study is Houston, Texas, a total of 25 sites across the nation are hosting investigations into this treatment."

Answered by AI

How many individuals will be enrolled in this trial?

"Affirmative. Per the details posted on clinicaltrials.gov, this study is actively seeking participants and was originally published on February 3rd 2021 with a most recent update dated May 16th 2022. Currently there are 36 spots to be filled at one medical centre."

Answered by AI

Has this type of clinical trial been attempted before?

"Control has been clinically studied since 2007, when Eli Lilly and Company launched the first of 20 trials. Subsequently granted N/A approval, there are currently 24 different studies involving Control taking place in 12 cities across 9 countries."

Answered by AI

Does this research program include individuals who are over forty years of age?

"This study seeks participants aged 40 to 65 years of age."

Answered by AI

What criteria must participants fulfill to be accepted in this research project?

"The current clinical trial is open to 36 individuals aged 40-65 with diabetic retinopathy. To be eligible, participants must meet the following age criteria: being between 40 and 65 years old."

Answered by AI

Is recruitment currently underway for this experiment?

"Affirmative. According to the information posted on clinicaltrials.gov, this trial - first published 2/3/2021 and updated 5/16/2022 - is presently in search of 36 patients from a single site."

Answered by AI

Is Control a dependable option for individuals?

"With only preliminary evidence of its safety, our team has assigned Control a score of 2 on the scale. As this is not yet a Phase 3 trial, there is no proof that it can produce any desired effect."

Answered by AI
Recent research and studies
~16 spots leftby Dec 2025