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What is Metadate Cd
MethylphenidateThe Generic name of this drug
Treatment SummaryMethylphenidate is a stimulant medication used to treat Attention-Deficit/Hyperactivity Disorder (ADHD) and narcolepsy. It is sold under the brand names Ritalin, Concerta, and Biphentin and is typically used with other therapies such as psychological, educational, and cognitive behavior therapy to improve symptoms like distractibility, short attention span, hyperactivity, emotional lability, and impulsivity. Methylphenidate works by increasing the presence of norepinephrine and dopamine in the brain. It is generally safe and effective and can be prescribed to both adults and children. However, it has
Methylphenidate Hydrochlorideis the brand name
Metadate Cd Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Methylphenidate Hydrochloride
Methylphenidate
1955
490
Effectiveness
How Metadate Cd Affects PatientsMethylphenidate is a drug that contains two different components, the d- and l-isomers. The d-isomer is more effective than the l-isomer in producing its effects. Studies have shown that it binds to dopamine-rich areas of the brain, especially in the prefrontal cortex, which is involved in ADHD. In animals, methylphenidate has been shown to increase physical activity and cause repetitive behaviors.
How Metadate Cd works in the bodyMethylphenidate works by increasing the amount of norepinephrine and dopamine in the brain. This can help improve attention and memory, which is especially beneficial for people with ADHD. It is believed that methylphenidate helps by filling the gaps caused by genetic abnormalities in the dopamine transporter gene, D4 receptor gene, and D2 receptor gene. Higher doses increase activity throughout the brain, while lower doses more selectively target the prefrontal cortex, which is important for ADHD. Additionally, methylphenidate's abilities to reduce impulsivity and movement are due to its effects on alpha-1 adrenergic receptors.
When to interrupt dosage
The proposed measure of Metadate Cd is contingent on the recognized affliction. The amount of dosage fluctuates, as per the technique of delivery specified in the table below.Condition
Dosage
Administration
Attention Deficit Hyperactivity Disorder
20.0 mg, , 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg, 27.0 mg, 36.0 mg, 54.0 mg, 50.0 mg, 5.0 mg, 2.5 mg, 5.0 mg/mL, 10.0 mg/mL, 18.0 mg, 80.0 mg, 15.0 mg, 10.0 mg/hour, 20.0 mg/hour, 15.0 mg/hour, 30.0 mg/hour, 30.0 mg/mL, 6.0 mg/mL, 7.5 mg/mL, 9.0 mg/mL, 8.6 mg, 25.9 mg, 17.3 mg, 1.0 mg/mL, 2.0 mg/mL, 25.0 mg, 35.0 mg, 55.0 mg, 70.0 mg, 85.0 mg, 100.0 mg, 45.0 mg, 72.0 mg, 63.0 mg
, Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, chewable, Tablet, chewable - Oral, Solution, Solution - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Chewable, Extended Release, Tablet, Chewable, Extended Release - Oral, Transdermal, Patch, Patch - Transdermal, Suspension, extended release, Suspension, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Narcolepsy
20.0 mg, , 30.0 mg, 40.0 mg, 10.0 mg, 60.0 mg, 27.0 mg, 36.0 mg, 54.0 mg, 50.0 mg, 5.0 mg, 2.5 mg, 5.0 mg/mL, 10.0 mg/mL, 18.0 mg, 80.0 mg, 15.0 mg, 10.0 mg/hour, 20.0 mg/hour, 15.0 mg/hour, 30.0 mg/hour, 30.0 mg/mL, 6.0 mg/mL, 7.5 mg/mL, 9.0 mg/mL, 8.6 mg, 25.9 mg, 17.3 mg, 1.0 mg/mL, 2.0 mg/mL, 25.0 mg, 35.0 mg, 55.0 mg, 70.0 mg, 85.0 mg, 100.0 mg, 45.0 mg, 72.0 mg, 63.0 mg
, Oral, Capsule, extended release - Oral, Capsule, extended release, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, chewable, Tablet, chewable - Oral, Solution, Solution - Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Chewable, Extended Release, Tablet, Chewable, Extended Release - Oral, Transdermal, Patch, Patch - Transdermal, Suspension, extended release, Suspension, extended release - Oral, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral
Warnings
Metadate Cd has fourteen contraventions, so it should not be blended with any of the conditions shown in the below table.Metadate Cd ContraindicationsCondition
Risk Level
Notes
advanced arteriosclerosis
Do Not Combine
Gilles de la Tourette syndrome
Do Not Combine
Thyrotoxicosis
Do Not Combine
Pulse Frequency
Do Not Combine
Open-angle glaucoma
Do Not Combine
Hypertensive disease
Do Not Combine
Pulse Frequency
Do Not Combine
Tension
Do Not Combine
Generalized Anxiety Disorder
Do Not Combine
symptomatic cardiovascular disease
Do Not Combine
Gilles de la Tourette's Syndrome
Do Not Combine
Pheochromocytomas
Do Not Combine
Tic, Motor
Do Not Combine
Agitation
Do Not Combine
Common Metadate Cd Drug Interactions
Drug Name
Risk Level
Description
Desflurane
Major
Methylphenidate may increase the hypertensive activities of Desflurane.
Diethyl ether
Major
Methylphenidate may increase the hypertensive activities of Diethyl ether.
Enflurane
Major
Methylphenidate may increase the hypertensive activities of Enflurane.
Halothane
Major
Methylphenidate may increase the hypertensive activities of Halothane.
Isoflurane
Major
Methylphenidate may increase the hypertensive activities of Isoflurane.
Metadate Cd Toxicity & Overdose RiskOverdosing on amphetamine can lead to symptoms such as vomiting, restlessness, trembling, increased reflexes, muscle spasms, seizures, feeling very good, confusion, seeing or hearing things that aren't real, restlessness, heavy sweating, flushed skin, headache, extreme body temperature, rapid heartbeat, abnormal heart rhythms, high blood pressure, wide open pupils, and dry mouth. The lowest toxic dose in mice is 190mg/kg when taken orally.
Metadate Cd Novel Uses: Which Conditions Have a Clinical Trial Featuring Metadate Cd?
84 active clinical studies are being conducted to assess the effectiveness of Metadate Cd in treating Attention Deficit Hyperactivity Disorder.Condition
Clinical Trials
Trial Phases
Attention Deficit Hyperactivity Disorder
71 Actively Recruiting
Phase 4, Not Applicable, Phase 1, Phase 2, Phase 3, Early Phase 1
Narcolepsy
10 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4, Phase 1
Metadate Cd Reviews: What are patients saying about Metadate Cd?
5Patient Review
12/8/2013 We've noticed a significant decline in the effectiveness of this medication since switching to the generic brand. Has anyone else experienced this? We'd love to hear any suggestions.
4.7Patient Review
1/5/2012 I have found that this drug works best for my kids, one with ADD and the other with ADHD and autism. I know it's also called Ritalin, but Metadate CD is released into the brain differently than Ritalin and doesn't have nearly as many side effects. I've been a very happy parent with this drug because it has gotten my son into the gifted program at school. It helps him focus and concentrate easier. He is very smart and gets along with all different kinds of kids.
4.3Patient Review
9/5/2012 I've found that 30mg of Metadate twice a day works really well for me. I'm able to stay focused and haven't had any issues with appetite loss, which I've experienced with other medications.
4.3Patient Review
8/9/2013 I've been taking this drug for years and it's helped me a lot. I'm more calm and focused, which has been great for school and other tasks. I do get some side effects from the medication, but nothing that's too bad or unmanageable.
4Patient Review
3/17/2013 My daughter has been taking Metadata CD 30mgs for the last year. It works great. U can tell when it kicks in and when it wears off, usually around 4:30 it's very hard for her to do homework independently.
4Patient Review
2/12/2015 My son was on this medication for nearly two years. Last year, he developed very low white blood cells and began having mouth sores once or twice a month from January to November. In December, I decided to take him off the medication; his health improved immediately. Otherwise, this medication worked perfectly for him.
4Patient Review
6/4/2014 We've seen such a significant difference in our child's behavior since starting this treatment. The whole family is thrilled!
4Patient Review
2/14/2017 I've been taking this drug for nine years, since I was nine. It's effective but there is a chance of long-term brain damage that causes depression and schizophrenia like symptoms. I'm experiencing those now.
3.7Patient Review
9/21/2012 My 12 year old daughter has been on Metadate 40 mg one per day for about 3 months and it seems to work well for her. We are still experiencing days when she isn't able to sit still or stop talking (most of the time jumping from one subject to the next,without finishing).
3Patient Review
8/8/2012 I felt more energetic and focused after taking this treatment.
Patient Q&A Section about metadate cd
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Metadate CD the same as Ritalin?
"Metadate CD can improve focus and decrease impulsivity and hyperactivity for some patients with the condition. It contains the same active ingredient as medications like Ritalin and Daytrana."
Answered by AI
What does Metadate CD mean?
"Metadate CD is a drug used to treat attention deficit disorder (ADD), attention deficit hyperactivity disorder (ADHD), and narcolepsy. It is a central nervous system (CNS) stimulant."
Answered by AI
What is the difference between Metadate CD and ER?
"The difference between Metadate CD and Metadate ER is that Metadate CD is a once-a-day capsule with biphasic release while Metadate ER is a tablet given two to three times per day. Metadate ER may be titrated to eliminate the need for midday dosing."
Answered by AI
Has Metadate CD been discontinued?
"The brand name Metadate CD has been discontinued by the manufacturer and is no longer available. All brand name Metadate CD National Drug Codes have been terminated by the Centers for Medicare and Medicaid Services."
Answered by AI