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Buspirone for Opioid Withdrawal
Study Summary
This trial will test if buspirone can help people with opioid use disorder who are going through a stepwise taper.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2016 Phase 4 trial • 175 Patients • NCT00875836Trial Design
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Who is running the clinical trial?
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- I am between 18 and 75 years old.You want to stop using opioids and need help to do so.You have a mental or physical condition that may make it difficult for you to take part in the study. This will be explained in a separate form that protects your privacy.I am not allergic to the study medication and am not taking any drugs that could interfere with it.I have low blood pressure or a heart rhythm issue.You currently have a serious problem with using opioids and are physically dependent on them.
- Group 1: opioid stepwise taper + lofexidine
- Group 2: opioid stepwise taper + placebo
- Group 3: opioid stepwise taper + buspirone
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
I am interested in enrolling for the research, what are the prerequisites?
"This study is looking for 100 individuals aged 18-75 who suffer from anxiety and currently use opioids. Most importantly, applicants must be physically dependent on opioids, have an opioid positive urine sample, and be interested in detoxing from opioids."
Has Buspirone been federally recognized as a safe and effective medication?
"Buspirone has received a score of 2, as there is some evidence for its safety but none yet for efficacy."
Are patients currently being accepted for this trial?
"This study, which was first posted on December 15th 2022 and last edited November 2nd of the same year, is not currently looking for participants. However, there are 713 other clinical trials that patients can look into enrolling in."
Does this clinical trial have an age limit for participants?
"The age range for patients that are being recruited for this trial are between 18-75 years old."
Who else is applying?
What state do they live in?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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