Loteprednol Etabonate

Eye Pain, Eye, Conjunctivitis + 1 more
Treatment
5 Active Studies for Loteprednol Etabonate

What is Loteprednol Etabonate

Loteprednol etabonateThe Generic name of this drug
Treatment SummaryLoteprednol Etabonate (LE) is an anti-inflammatory steroid used to treat inflammation and pain in the eyes, nose, and after ocular surgery. It is used in eye drops and a nasal spray for allergies. LE is designed to be active only at the site of application and quickly metabolized to reduce the chance of side effects. It is the first ocular steroid that is taken twice a day, which makes it easier for patients to remember to take it.
Inveltysis the brand name
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Loteprednol Etabonate Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Inveltys
Loteprednol etabonate
2018
3

Effectiveness

How Loteprednol Etabonate Affects PatientsLoteprednol etabonate (LE) is a special type of corticosteroid used to treat inflammation. It is 4.3 times more powerful than dexamethasone. The body can break down LE into non-toxic molecules, and LE can be absorbed through the eyes and skin. Once the body breaks down LE it produces an inactive metabolite that is easier for the body to eliminate.
How Loteprednol Etabonate works in the bodyLoteprednol etabonate is a type of corticosteroid that works to reduce inflammation in the body. It is known to reduce swelling, increase capillary dilation, and block the formation of fibrin, scarring and collagen. Corticosteroids are also thought to reduce the production of prostaglandins, which are molecules associated with inflammation. This is done by preventing the release of a compound called arachidonic acid from cells. By doing this, loteprednol etabonate is able to reduce inflammation following ocular surgery and manage post-operative pain.

When to interrupt dosage

The suggested measure of Loteprednol Etabonate is dependent upon the diagnosed state, including Dry Eye Syndrome, Eye and Ocular Inflammation. The measure of dosage can be discovered in the table beneath, relying on the technique of delivery (e.g. Suspension - Topical or Gel).
Condition
Dosage
Administration
Eye Pain
10.0 mg/mL, , 0.0038 mg/mg, 2.5 mg/mL
Suspension - Topical, Suspension, Topical, , Gel - Ophthalmic, Gel, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Eye
10.0 mg/mL, , 0.0038 mg/mg, 2.5 mg/mL
Suspension - Topical, Suspension, Topical, , Gel - Ophthalmic, Gel, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Conjunctivitis
10.0 mg/mL, , 0.0038 mg/mg, 2.5 mg/mL
Suspension - Topical, Suspension, Topical, , Gel - Ophthalmic, Gel, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic
Dry Eye Syndrome
10.0 mg/mL, , 0.0038 mg/mg, 2.5 mg/mL
Suspension - Topical, Suspension, Topical, , Gel - Ophthalmic, Gel, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic

Warnings

Loteprednol Etabonate has four contraindications and should be avoided when encountering the situations set out in the subsequent table.Loteprednol Etabonate Contraindications
Condition
Risk Level
Notes
Viral Infections of the Corneas
Do Not Combine
Eye
Do Not Combine
Viral Infections of the Corneas
Do Not Combine
Eye Infections, Fungal
Do Not Combine
Common Loteprednol Etabonate Drug Interactions
Drug Name
Risk Level
Description
Loteprednol Etabonate Toxicity & Overdose RiskThe most common side effects reported from using loteprednol etabonate are eye pain and cloudiness in the eye due to surgery. The medication does not enter the bloodstream when used around the eyes, so it will not affect mothers or unborn babies. Animal studies have not shown any cancer-causing potential, nor any genetic damage. Overdosing on loteprednol etabonate is not expected when used around the eyes.
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Loteprednol Etabonate Novel Uses: Which Conditions Have a Clinical Trial Featuring Loteprednol Etabonate?

20 ongoing trials are examining the potential of Loteprednol Etabonate to reduce symptoms of Dry Eye Syndrome, Eye Pain and Ocular Inflammation.
Condition
Clinical Trials
Trial Phases
Eye Pain
1 Actively Recruiting
Phase 1
Conjunctivitis
0 Actively Recruiting
Eye
0 Actively Recruiting
Dry Eye Syndrome
5 Actively Recruiting
Not Applicable, Phase 3, Phase 4, Phase 2

Loteprednol Etabonate Reviews: What are patients saying about Loteprednol Etabonate?

5Patient Review
12/1/2009
Loteprednol Etabonate for Allergic Conjunctivitis
This medication quickly and effectively alleviated the pain I was experiencing from allergic conjunctivitis.
5Patient Review
9/24/2020
Loteprednol Etabonate for Inflammation of the Eye
The eye drops are very effective, but they're also quite expensive.
3.7Patient Review
5/2/2013
Loteprednol Etabonate for Inflammation of the Eye
I would sometimes experience dizzy spells.
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Patient Q&A Section about loteprednol etabonate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is loteprednol Etabonate a steroid?

"Lotemax is a corticosteroid that is used to treat eye swelling that is caused by surgery, infection, allergies, and other conditions."

Answered by AI

How long can you use loteprednol eye drops?

"For adults, instill one to two drops of the medication into the affected eye four times a day. The course of treatment should not exceed two weeks. For children, the dosage must be determined by a doctor."

Answered by AI

What is Loteprednol Etabonate used for?

"Loteprednol can be used to relieve eye pain, redness, and swelling caused by certain eye problems or eye surgery. It can also be used to temporarily relieve itching of the eye caused by seasonal allergic conjunctivitis."

Answered by AI

How long does it take for loteprednol Etabonate to work?

"Although the amount of time it takes for Eysuvis to work may differ among individuals, most people should start to see a progressive improvement in their dry eye symptoms within a few days of starting treatment. The greatest improvement is usually seen after 15 days of treatment."

Answered by AI

Clinical Trials for Loteprednol Etabonate

Have you considered Loteprednol Etabonate clinical trials? We made a collection of clinical trials featuring Loteprednol Etabonate, we think they might fit your search criteria.
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