Lotemax

Chickenpox, Iritis, Inflammation + 10 more
Treatment
14 FDA approvals
20 Active Studies for Lotemax

What is Lotemax

LoteprednolThe Generic name of this drug
Alrexis the brand name
image of different drug pills on a surface
Lotemax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Alrex
Loteprednol
1998
16

Approved as Treatment by the FDA

Loteprednol, otherwise called Alrex, is approved by the FDA for 14 uses like Inflammation and ocular bacterial infections .
Inflammation
Used to treat Inflammation in combination with Tobramycin
ocular bacterial infections
Used to treat ocular bacterial infections in combination with Tobramycin
Ocular Inflammation
Conjunctivitis infective
Iritis
Seasonal Allergic Conjunctivitis
Conjunctivitis
Herpes Zoster Keratitis
Helps manage Herpes Zoster Keratitis
Inflammation
Used to treat Inflammation in combination with Tobramycin
Conjunctivitis
Iritis
Eye
Cyclitis
Superficial punctate keratitis
Helps manage Superficial punctate keratitis

When to interrupt dosage

The quantity of Lotemax is contingent upon the determined affliction, like Ocular Inflammation, Conjunctivitis infective and Herpes Zoster Keratitis. The dosage diverges as per the technique of delivery (e.g. Gel - Ophthalmic or Suspension / drops) featured in the table beneath.
Condition
Dosage
Administration
Inflammation
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Rosacea
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Conjunctivitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Conjunctivitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Cyclitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Eye
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Chickenpox
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Communicable Diseases
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Superficial punctate keratitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
ocular bacterial infections
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Iritis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Seasonal Allergic Conjunctivitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Herpes Zoster Keratitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic

Warnings

Lotemax Contraindications
Condition
Risk Level
Notes
Keratitis, Dendritic
Do Not Combine
conjunctiva
Do Not Combine
Herpes Simplex
Do Not Combine
Chickenpox
Do Not Combine
Vaccinia
Do Not Combine
epithelial herpes simplex keratitis
Do Not Combine
Eye Infections, Fungal
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Loteprednol may interact with Pulse Frequency
There are 20 known major drug interactions with Lotemax.
Common Lotemax Drug Interactions
Drug Name
Risk Level
Description
2,4-thiazolidinedione
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with 2,4-thiazolidinedione.
AICA ribonucleotide
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with AICA ribonucleotide.
AMG-222
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with AMG-222.
Acarbose
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with Acarbose.
Acetohexamide
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with Acetohexamide.
image of a doctor in a lab doing drug, clinical research

Lotemax Novel Uses: Which Conditions Have a Clinical Trial Featuring Lotemax?

Currently, 198 active studies are being conducted to assess the potential of Lotemax in alleviating Seasonal Allergic Conjunctivitis, Iritis and Ocular Inflammation.
Condition
Clinical Trials
Trial Phases
Eye
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Superficial punctate keratitis
0 Actively Recruiting
Iritis
0 Actively Recruiting
Herpes Zoster Keratitis
0 Actively Recruiting
Rosacea
2 Actively Recruiting
Early Phase 1, Phase 2
Conjunctivitis
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Chickenpox
4 Actively Recruiting
Phase 4, Phase 3
Cyclitis
0 Actively Recruiting
Inflammation
58 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Seasonal Allergic Conjunctivitis
0 Actively Recruiting

Lotemax Reviews: What are patients saying about Lotemax?

5Patient Review
11/1/2013
Lotemax for Allergic Conjunctivitis
I've been using Lotemax for over two years now and it's been great. I was previously using Durezel, but my doctors were concerned about the pressure it was putting on my eye. With Lotemax, we don't have to worry about that. The only downside is that I sometimes get brief headaches and pain in my eyes, and once in a while my blood vessels will break on the whites of my eyes.
5Patient Review
7/26/2013
Lotemax for Inflammation of the Eye
When I first started using Lotemax eye drops, four times per day, the results were immediate. Redness, watery eyes, dry eyes disappeared. Those good results lasted about a month. The eye drops seem to have a rebound effect; however, I am beginning to think there is no cure.
5Patient Review
9/7/2014
Lotemax for Allergic Conjunctivitis
This was the fifth medication we tried, and my eyes felt 100% better after just one dose. I'm now only using one drop a day in the morning, and my eyelids are no longer red or scaly.
5Patient Review
12/3/2015
Lotemax for Inflammation of the Eye
I've been using this eye drop for over 15 years to combat my dry eyes. It's by far the most effective medication I've tried, and I'm grateful that it doesn't have any significant side effects.
5Patient Review
1/29/2017
Lotemax for Inflammation of the Eye Following Surgery
After my corneal transplant, the doctor prescribed this medication. I haven't had any issues with optical hypertension like I did with prednisone. It's a bit spendy since there is no generic, but you don't need very much of it.
4Patient Review
3/3/2013
Lotemax for Inflammation of the Eye Following Surgery
Lotemax unfortunately exacerbated my dry eye syndrome. I got more relief from Retaine MGD, so I stopped using Lotemax.
3.7Patient Review
3/3/2016
Lotemax for Inflammation of the Eye
Lotemax was highly effective in reducing the inflammation in my eye. However, after using it for a prolonged period of time, I started to bruise easily. Since it is a steroid, I have had to discontinue use.
3Patient Review
7/21/2013
Lotemax for Inflammation of the Iris and Ciliary Body of the Eye
Providers, please be mindful of the cost of the medication you prescribe to your patients. This 1/8 ounce ointment costs $202.49 cash price. A generic corticosteroid would have been just as effective but much cheaper. The Health Care Field needs to be more conscious of this!
2.7Patient Review
4/16/2014
Lotemax for Inflammation of the Eye Following Surgery
I've had two cornea transplants, in 2006 and 2012. I was prescribed this medication to help prevent rejection, after being told that prenisone would raise my eye pressure. For the last several months, though, I've been suffering from dry eyes. They burn and water continually, like I'm crying. It's really miserable. There's nothing I can do to improve my quality of life.
2.7Patient Review
7/7/2013
Lotemax for Inflammation of the Eye
I've been using this medication for about three days to help with the pressure in my eye following surgery, and so far I haven't experienced any negative side effects. It's too bad that the price is so high though; it seems like senior citizens are being taken advantage of.
2.7Patient Review
7/17/2013
Lotemax for Inflammation of the Eye
I have ocular roseacea, which causes swollen and red eyelids. When I first used this medication, it caused a stinging sensation on my eyelids.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about lotemax

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Lotemax a strong steroid?

"Examples of soft steroids include loteprednol, Alrex, and Lotemax."

Answered by AI

How long does it take for Lotemax to work?

"It may take up to 2 days for Lotemax to work. If your symptoms have not improved after 2 days, talk with your healthcare provider."

Answered by AI

Is Lotemax an antibiotic for the eye?

"Loteprednol is not an antibiotic, but is a steroid that treats inflammation. It is available in a combination eye drop with an antibiotic called tobramycin."

Answered by AI

What is Lotemax used for?

"Loteprednol is used to treat swelling and pain after cataract surgery and to reduce eye redness, itching, and swelling caused by seasonal allergies."

Answered by AI

Clinical Trials for Lotemax

Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Waitlist Available
Has No Placebo
UConn HealthCutter Lindbergh, Ph.D.
Image of Department of Nutritional Sciences in Storrs, United States.

Freeze-dried Grape Powder for Healthy Aging

50 - 75
All Sexes
Storrs, CT
The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, and metabolism that are known to change with aging. Grapes contain several nutrients and antioxidant polyphenols such as resveratrol, quercetin, vitamin K and fiber, which are known to promote heart and immune health. However, the effects of grapes on altering immune profiles within the context of aging is not well understood. Therefore, this study will explore how daily grape consumption impacts certain markers of immunity in healthy middle- and older-aged adults. The main study procedures include consumption of a freeze-dried grape powder and control powder (which tastes the same but has none of the grape compounds that are being studied) mixed with water as a beverage on a daily basis for 4 weeks each. The investigators will additionally ask that participants avoid eating grapes and certain other antioxidant/grape-related foods and beverages throughout the 13-week study. Participants will additionally be asked to complete surveys about their diet, physical activity, and medical history, as well as provide blood samples and body weight measures throughout the course of the study. Participation in the study is expected to last about 6.25 hours over the course of 13 weeks and will include 7 visits.
Recruiting
Paid Trial
Department of Nutritional Sciences
Have you considered Lotemax clinical trials? We made a collection of clinical trials featuring Lotemax, we think they might fit your search criteria.Go to Trials
Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.
Recruiting
Has No Placebo
School of Public Health
Image of Tesla MedBed at Tampa-FL in Tampa, United States.

Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL
Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.
Recruiting
Online Trial
Tesla MedBed at Tampa-FL (+1 Sites)James Z Liu, MD, PhD
Have you considered Lotemax clinical trials? We made a collection of clinical trials featuring Lotemax, we think they might fit your search criteria.Go to Trials
Image of UCSF in San Francisco, United States.

Moisturizers for Aging

65+
All Sexes
San Francisco, CA
This is a randomized, investigator-blinded, self-controlled pilot study of the physiologic response to topical moisturizers among older adults with dry skin. The overarching hypothesis is that skin barrier decline is an important source of chronic inflammation, and that skin barrier restoration with moisturizers can reduce serum biomarkers of inflammation. The primary objective is to determine the feasibility for a larger trial, and the secondary objectives are to determine the extent to which measures of serum inflammation, skin barrier function, and the skin microbiome change in response to moisturizers. Participants will be asked to apply one of two topical moisturizers that are widely available over the counter in the US (Vaseline® 100% pure petroleum jelly or CeraVe® moisturizing cream) once daily for 4 weeks to the front of the torso, buttocks, arms, and legs. Subjects will act as their own control (i.e. they will be asked to apply the study moisturizer they are randomized to for one intervention period (4 weeks) and not to apply topical moisturizers for the other 4- week intervention period). Participants will be randomized in a 1:1:1:1 ratio to one of 4 treatment groups: i. no intervention then CeraVe; ii. CeraVe then no intervention; iii. no intervention then Vaseline; iv. Vaseline then no intervention. At each visit (baseline, week 4, and week 8), participants will undergo skin barrier testing, skin microbiome sampling, and phlebotomy to measure serum inflammatory markers.
Phase 4
Recruiting
UCSFKatrina Abuabara, MD
Have you considered Lotemax clinical trials? We made a collection of clinical trials featuring Lotemax, we think they might fit your search criteria.Go to Trials
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security