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What is Lotemax
LoteprednolThe Generic name of this drug
Alrexis the brand name
Lotemax Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Alrex
Loteprednol
1998
16
Approved as Treatment by the FDA
Loteprednol, otherwise called Alrex, is approved by the FDA for 10 uses like Ocular Inflammation and Herpes Zoster Keratitis .Ocular Inflammation
Herpes Zoster Keratitis
Helps manage Herpes Zoster Keratitis
Eye
Iritis
Inflammation
Used to treat Inflammation in combination with Tobramycin
Conjunctivitis infective
Cyclitis
Seasonal Allergic Conjunctivitis
Superficial punctate keratitis
Helps manage Superficial punctate keratitis
ocular bacterial infections
Used to treat ocular bacterial infections in combination with Tobramycin
When to interrupt dosage
The quantity of Lotemax is contingent upon the determined affliction, like Ocular Inflammation, Conjunctivitis infective and Herpes Zoster Keratitis. The dosage diverges as per the technique of delivery (e.g. Gel - Ophthalmic or Suspension / drops) featured in the table beneath.Condition
Dosage
Administration
Chickenpox
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Iritis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Inflammation
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Eye infection viral
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Rosacea
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Superficial punctate keratitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Conjunctivitis infective
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Eye
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Seasonal Allergic Conjunctivitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Ocular Inflammation
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Herpes Zoster Keratitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Cyclitis
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
ocular bacterial infections
, 2.0 mg/mL, 0.005 mg/mg, 5.0 mg/mL, 0.2 %, 0.5 %
, Ophthalmic, Suspension / drops, Suspension / drops - Ophthalmic, Ointment, Ointment - Ophthalmic, Suspension, Suspension - Ophthalmic, Gel, Gel - Ophthalmic
Warnings
Lotemax ContraindicationsCondition
Risk Level
Notes
Keratitis, Dendritic
Do Not Combine
conjunctiva
Do Not Combine
epithelial herpes simplex
Do Not Combine
Varicella
Do Not Combine
Vaccinia
Do Not Combine
epithelial herpes simplex keratitis
Do Not Combine
Eye Infections, Fungal
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Loteprednol may interact with Pulse Frequency
Common Lotemax Drug Interactions
Drug Name
Risk Level
Description
2,4-thiazolidinedione
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with 2,4-thiazolidinedione.
AICA ribonucleotide
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with AICA ribonucleotide.
AMG-222
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with AMG-222.
Acarbose
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with Acarbose.
Acetohexamide
Moderate
The risk or severity of hyperglycemia can be increased when Loteprednol is combined with Acetohexamide.
Lotemax Novel Uses: Which Conditions Have a Clinical Trial Featuring Lotemax?
Currently, 198 active studies are being conducted to assess the potential of Lotemax in alleviating Seasonal Allergic Conjunctivitis, Iritis and Ocular Inflammation.Condition
Clinical Trials
Trial Phases
Inflammation
171 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Conjunctivitis infective
0 Actively Recruiting
Superficial punctate keratitis
0 Actively Recruiting
Eye
0 Actively Recruiting
Iritis
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Seasonal Allergic Conjunctivitis
0 Actively Recruiting
Eye infection viral
0 Actively Recruiting
Cyclitis
0 Actively Recruiting
Herpes Zoster Keratitis
0 Actively Recruiting
Chickenpox
3 Actively Recruiting
Phase 2, Phase 1
Rosacea
8 Actively Recruiting
Not Applicable, Early Phase 1, Phase 2, Phase 4
Ocular Inflammation
3 Actively Recruiting
Phase 2, Phase 4, Phase 3
Lotemax Reviews: What are patients saying about Lotemax?
5Patient Review
11/1/2013 I've been using Lotemax for over two years now and it's been great. I was previously using Durezel, but my doctors were concerned about the pressure it was putting on my eye. With Lotemax, we don't have to worry about that. The only downside is that I sometimes get brief headaches and pain in my eyes, and once in a while my blood vessels will break on the whites of my eyes.
5Patient Review
7/26/2013 When I first started using Lotemax eye drops, four times per day, the results were immediate. Redness, watery eyes, dry eyes disappeared. Those good results lasted about a month. The eye drops seem to have a rebound effect; however, I am beginning to think there is no cure.
5Patient Review
9/7/2014 This was the fifth medication we tried, and my eyes felt 100% better after just one dose. I'm now only using one drop a day in the morning, and my eyelids are no longer red or scaly.
5Patient Review
12/3/2015 I've been using this eye drop for over 15 years to combat my dry eyes. It's by far the most effective medication I've tried, and I'm grateful that it doesn't have any significant side effects.
5Patient Review
1/29/2017 After my corneal transplant, the doctor prescribed this medication. I haven't had any issues with optical hypertension like I did with prednisone. It's a bit spendy since there is no generic, but you don't need very much of it.
4Patient Review
3/3/2013 Lotemax unfortunately exacerbated my dry eye syndrome. I got more relief from Retaine MGD, so I stopped using Lotemax.
3.7Patient Review
3/3/2016 Lotemax was highly effective in reducing the inflammation in my eye. However, after using it for a prolonged period of time, I started to bruise easily. Since it is a steroid, I have had to discontinue use.
3Patient Review
7/21/2013 Providers, please be mindful of the cost of the medication you prescribe to your patients. This 1/8 ounce ointment costs $202.49 cash price. A generic corticosteroid would have been just as effective but much cheaper. The Health Care Field needs to be more conscious of this!
2.7Patient Review
4/16/2014 I've had two cornea transplants, in 2006 and 2012. I was prescribed this medication to help prevent rejection, after being told that prenisone would raise my eye pressure. For the last several months, though, I've been suffering from dry eyes. They burn and water continually, like I'm crying. It's really miserable. There's nothing I can do to improve my quality of life.
2.7Patient Review
7/7/2013 I've been using this medication for about three days to help with the pressure in my eye following surgery, and so far I haven't experienced any negative side effects. It's too bad that the price is so high though; it seems like senior citizens are being taken advantage of.
2.7Patient Review
7/17/2013 I have ocular roseacea, which causes swollen and red eyelids. When I first used this medication, it caused a stinging sensation on my eyelids.
Patient Q&A Section about lotemax
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Lotemax a strong steroid?
"Examples of soft steroids include loteprednol, Alrex, and Lotemax."
Answered by AI
How long does it take for Lotemax to work?
"It may take up to 2 days for Lotemax to work. If your symptoms have not improved after 2 days, talk with your healthcare provider."
Answered by AI
Is Lotemax an antibiotic for the eye?
"Loteprednol is not an antibiotic, but is a steroid that treats inflammation. It is available in a combination eye drop with an antibiotic called tobramycin."
Answered by AI