What is Lomaira
PhentermineThe Generic name of this drug
Treatment SummaryPhentermine is an appetite suppressant that was approved as a part of an anti-obesity combination drug in 1959. It is related to amphetamine, but is classified as a Schedule IV drug due to its low risk of addiction. Phentermine is used in the short-term to manage weight and was approved alone or in combination with the drug topiramate in 2012.
Ionaminis the brand name
Lomaira Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ionamin
Phentermine
1959
292
Approved as Treatment by the FDA
Phentermine, also known as Ionamin, is approved by the FDA for 2 uses including Comorbidity and Regime of weight reduction .Comorbidity
Used to treat one related comorbidity in combination with Topiramate
Regime of weight reduction
Effectiveness
How Lomaira Affects PatientsPhentermine is thought to reduce appetite, possibly by increasing levels of the hormone leptin. It may also increase how much energy you burn at rest. People taking phentermine in clinical studies typically lost an average of 3.6 kg (about 8 pounds) over 2-24 weeks. After stopping taking phentermine, people were able to maintain this weight loss. Unlike some other medications related to amphetamines, phentermine does not cause central nervous system stimulation, high blood pressure, decreased effectiveness with long-term use, or changes in heart rhythm.
How Lomaira works in the bodyPhentermine works by releasing adrenaline in the brain, which stimulates the body to be on alert and reduces hunger signals. It also affects serotonin, dopamine, and norepinephrine levels, and weakly inhibits monoamine oxidase. Overall, this creates a state of alertness and reduces the feeling of hunger.
When to interrupt dosage
The measure of Lomaira is reliant upon the diagnosed situation, including Regime of weight reduction, Hyperlipidemia and Type 2 Diabetes. The dose fluctuates as per the technique of delivery (e.g. Oral or Tablet) featured in the table underneath.Condition
Dosage
Administration
Regime of weight reduction
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
Hypertensive disease
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
Comorbidity
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
High Cholesterol
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
Type 2 Diabetes
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
Disease
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
BMI >27 kg/m2
, 30.0 mg, 15.0 mg, 37.5 mg, 3.75 mg, 11.25 mg, 7.5 mg, 8.0 mg, 18.8 mg
Oral, Tablet, Tablet, orally disintegrating, , Tablet, orally disintegrating - Oral, Capsule, extended release, Capsule, extended release - Oral, Capsule, Tablet - Oral, Capsule - Oral
Warnings
Lomaira ContraindicationsCondition
Risk Level
Notes
Cardiovascular Diseases
Do Not Combine
Agitation
Do Not Combine
concomitant use or 14 days after discontinuation
Do Not Combine
Open-angle glaucoma
Do Not Combine
Hyperthyroidism
Do Not Combine
Drug abuse
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Phentermine may interact with Toxoplasma Infections
Common Lomaira Drug Interactions
Drug Name
Risk Level
Description
Iobenguane
Major
Phentermine can cause a decrease in the absorption of Iobenguane resulting in a reduced serum concentration and potentially a decrease in efficacy.
Methylene blue
Major
Phentermine may increase the serotonergic activities of Methylene blue.
Tretinoin
Major
The risk or severity of elevated intracranial pressure can be increased when Phentermine is combined with Tretinoin.
1-benzylimidazole
Minor
The therapeutic efficacy of 1-benzylimidazole can be decreased when used in combination with Phentermine.
4-Methoxyamphetamine
Minor
The risk or severity of hypertension can be increased when Phentermine is combined with 4-Methoxyamphetamine.
Lomaira Toxicity & Overdose RiskIn rats, the toxic dose of phentermine is 151mg/kg. Symptoms of overdose can include restlessness, shaking, overactive reflexes, fast breathing, confusion, aggression, hallucinations, and panic followed by fatigue and depression. It can also affect the cardiovascular system with rapid heart rate, abnormal heart rhythms, high or low blood pressure, and circulation failure. In the digestive system, it can cause nausea, vomiting, diarrhea, and stomach cramps. Treatment for acute overdose includes supportive care and stomach pumping with sedation with barbiturates. Chronic overdosing can lead to skin problems, difficulty sleeping, irritability, hyper
Lomaira Novel Uses: Which Conditions Have a Clinical Trial Featuring Lomaira?
104 active studies are currently investigating the potential of Lomaira to combat Type 2 Diabetes, facilitate Weight Reduction and treat Disease.Condition
Clinical Trials
Trial Phases
Type 2 Diabetes
93 Actively Recruiting
Phase 3, Phase 4, Not Applicable, Phase 2, Phase 1
BMI >27 kg/m2
0 Actively Recruiting
Disease
0 Actively Recruiting
Regime of weight reduction
0 Actively Recruiting
High Cholesterol
17 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 4
Comorbidity
0 Actively Recruiting
Hypertensive disease
0 Actively Recruiting
Lomaira Reviews: What are patients saying about Lomaira?
5Patient Review
9/27/2020 This is one of the best appetite suppressants I have tried. It has helped me lose 14 pounds in just 3 weeks with no change to my diet or exercise routine.
5Patient Review
10/12/2020 I am so pleased with how much weight I've been able to lose without feeling like I'm dieting. It's really helped me take care of my health and diabetes.
5Patient Review
10/6/2020 I was getting frustrated with other methods of weight loss, so I decided to speak with my doctor. He suggested Lomaira, and the results were amazing! I lost six pounds in the first month, which was a great success for me.
5Patient Review
8/2/2020 I've been carrying around extra weight since college and was in dire need of assistance. A friend recommended Lomaira, so I consulted my doctor about it. They said it was okay to use, so I've been taking it for more than three months now. After the first month, I saw a five pound difference. This really motivated me to start eating better and working out, which I'm excited to see the results of in the future.
5Patient Review
7/23/2020 I've been on this medication for a short time, and it's already helping me out. I changed my lifestyle to accommodate it โ more walking, better eating habits, more sleep, drinking lots of water, etc. It's helped me lose weight and feel more energetic. Plus, my clothes are fitting better now.
5Patient Review
7/16/2020 I think the price is more than fair, especially given how well this drug works. I have seen no negative side effects and feel better already--not to mention that my appetite is much more under control. With my doctor's help, I'm setting some ambitious goals and am confident that Lomaira will assist me in reaching them.
5Patient Review
7/9/2020 I saw that Lomaira worked well for my cousin, so I decided to give it a try with my doctor's approval. I've been taking the pills for about a month now and have already lost 9 pounds.
5Patient Review
12/4/2020 I am extremely pleased with the results of this treatment. In just five weeks I've lost six pounds without making any serious changes to my exercise or diet routine. Additionally, I haven't experienced any negative side effects. This was definitely the best decision for me in terms of taking control of my health and starting my journey towards a healthier lifestyle.
5Patient Review
8/9/2020 I switched to Lomaira after my old weight loss pills stopped working well for me. My doctor recommended this, and I saw results within just a few weeks. It's been amazing so far!
5Patient Review
9/5/2020 I followed my doctor's recommendation and started using Lomaira a month ago. I saw a decrease in appetite within days, which helped me stick to a healthier diet and lose weight. I'm glad it's an FDA-approved medication so I know it's safe to use.
5Patient Review
9/14/2020 This drug really helped me lose weight- in just one month I went from a BMI of 30 to 27.5. Not only that, but it was affordable and didn't give me any negative side effects. I feel so much better now!
5Patient Review
11/16/2020 I decided to finally lose some weight and my friend recommended Lomaira. I saw my doctor first to check for any possible complications, but he gave me the go ahead. I've been taking it for a month now with no side effects. So far I'm really happy with the results!
5Patient Review
10/27/2020 I was really struggling to manage my weight, so I talked to my doctor about it. He recommended Lomaira and checked me for any possible complications. I've been taking it for more than two months now and have lost seven pounds--I'm really happy with the results!
5Patient Review
11/28/2020 When used in combination with a lifestyle change, this medicine is very effective! I have been able to steadily lose weight and reach my goals.
5Patient Review
8/25/2020 Lomaira has been a lifesaver for me. I tried two different diets with no success before being recommended this by my doctor. It's only been 8 weeks, and I'm already seeing results. I would definitely recommend this to anyone struggling with obesity.
5Patient Review
8/18/2020 I'm really pleased with how Lomaira has helped me lose weight. It definitely curbs my appetite, which makes it easier to cut down on calories. I highly recommend this medication for anyone struggling to lose weight.
5Patient Review
9/20/2020 Excellent results in less than 2 weeks! Iโve lost 10 lbs without even exercising. I had more energy and less appetite, no side effects, no dry mouth, no heart palps or anything else. I was 195 lbs 2 weeks ago and now I am 185 lbs with a smile on my face every day!
Patient Q&A Section about lomaira
How long can I stay on Lomaira?
"Lomaira can be used for short-term use, for up to 12 weeks." - Anonymous Online Contributor
Unverified Answer
What are the side effects of Lomaira?
"You may experience some of the following side effects: dizziness, dry mouth, difficulty sleeping, irritability, nausea, vomiting, diarrhea, or constipation. If you notice any of these effects lasting or getting worse, tell your doctor or pharmacist." - Anonymous Online Contributor
Unverified Answer
Is Lomaira as good as phentermine?
"The lowest strength of phentermine that is approved to be used three times a day is LOMAIRA. The37.5 mg dose of generic phentermine is the highest dose and is taken once a day before breakfast." - Anonymous Online Contributor
Unverified Answer
Does Lomaira help you lose weight?
"Lomaira may help you lose weight if used for three months as part of a diet and exercise routine. Patients may pay 50ยข per tablet for the duration of treatment." - Anonymous Online Contributor
Unverified Answer