Lidocaine And Prilocaine

Local Anaesthesia therapy

Treatment

1 FDA approval

0 Active Studies for Lidocaine And Prilocaine

Treatment for

Local Anaesthesia therapy

What is Lidocaine And Prilocaine

PrilocaineThe Generic name of this drug

Treatment SummaryLidocaine is a medication that has been used since the 1940s to numb tissues and provide local anesthesia. It works by blocking sodium channels, preventing the brain from receiving sensations from local tissues. It can also cause side effects such as vasodilation, hypotension, and irregular heart rate. It is also used to treat premature ejaculation and is available as a generic medication that is prescribed worldwide. It is even included in the World Health Organization's List of Essential Medicines.

Citanest Forteis the brand name

image of different drug pills on a surface

Lidocaine And Prilocaine Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Citanest Forte

Prilocaine

1965

Approved as Treatment by the FDA

Prilocaine, also known as Citanest Forte, is approved by the FDA for 1 uses such as Local Anaesthesia therapy .

Local Anaesthesia therapy

Effectiveness

How Lidocaine And Prilocaine Affects PatientsLidocaine is a drug that is used to reduce pain and numbness. It works by blocking sodium channels, which prevents the transmission of electrical signals in the body. This can lead to lower blood pressure, slower heart rate, and other issues like heart arrhythmia. It takes effect quickly, usually within one minute when administered intravenously and fifteen minutes when injected intramuscularly. The effects can last up to 90 minutes. The effectiveness of lidocaine may be reduced in the presence of inflammation, due to acidosis and increased production of inflammatory chemicals.

How Lidocaine And Prilocaine works in the bodyLidocaine is a type of local anesthetic used to numb certain areas of the body. It does this by blocking nerve signals from being sent to the brain. It does this by interacting with sodium ion channels on the surface of nerve cells. When lidocaine binds to these channels, it prevents them from being able to open and send out a signal. In addition to numbing the area locally, lidocaine can also have effects on the central nervous system and cardiovascular system. It can cause stimulation of the nervous system and also reduce electrical excitability and contraction force of the heart muscle.

When to interrupt dosage

The portion of Lidocaine And Prilocaine is influenced by the diagnosed condition, such as External auditory canal structure, Local anesthesia and Local anesthesia. The measure of dosage likewise varies in accordance with the technique of delivery (e.g. Cream; Kit; Solution or Topical) presented in the table below.

Condition

Dosage

Administration

Local Anaesthesia therapy

, 40.0 mg/mL, 0.025 mg/mg, 2.5 %, 50.0 mg/mL, 2.5 mg/mg, 0.05 mg/mg

, Subcutaneous, Injection, solution, Injection, solution - Subcutaneous, Topical, Cream - Topical, Cream, Periodontal, Gel, Gel - Periodontal, Dental, Injection, solution - Dental, Kit - Topical, Kit, Infiltration, Gel - Topical, Solution, Solution - Infiltration, Cutaneous, Spray, Spray - Cutaneous, Patch, Patch - Topical, Submucosal, Injection, solution - Submucosal, Parenteral, Injection, solution - Parenteral, Ointment, Ointment - Topical, Intra-articular; Intramuscular; Topical, Cream; Kit, Cream; Kit - Topical, Kit - Cutaneous; Topical, Cutaneous; Topical, Oral; Topical

Warnings

Lidocaine And Prilocaine has one known contraindication, so it should not be implemented for the conditions in the accompanying table.Lidocaine And Prilocaine Contraindications

Condition

Risk Level

Notes

Methemoglobinemia

Do Not Combine

Congenital methaemoglobinaemia

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Lidocaine And Prilocaine.

Common Lidocaine And Prilocaine Drug Interactions

Drug Name

Risk Level

Description

Azelastine

Major

Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Azelastine.

Ethanol

Major

Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Ethanol.

Oliceridine

Major

The risk or severity of hypotension, sedation, death, somnolence, and respiratory depression can be increased when Prilocaine is combined with Oliceridine.

Technetium Tc-99m tilmanocept

Major

Prilocaine may decrease effectiveness of Technetium Tc-99m tilmanocept as a diagnostic agent.

Thalidomide

Major

Prilocaine may increase the central nervous system depressant (CNS depressant) activities of Thalidomide.

Lidocaine And Prilocaine Toxicity & Overdose RiskTaking too much lidocaine can lead to symptoms such as tingling around the mouth, dizziness, increased sensitivity to noise and touch, twitching muscles, and seizures. These signs must not be confused with psychological symptoms. Unconsciousness and long-lasting seizures may follow. Low oxygen and high carbon dioxide levels can happen quickly during a seizure due to increased muscle activity, as well as obstruction of the airways. In very severe cases, this can lead to death. Acidosis can increase the drug's toxic effects. The heart may also be affected in severe cases, causing low blood pressure, slowed heart rate, abnormal heart rhythms

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Lidocaine And Prilocaine Novel Uses: Which Conditions Have a Clinical Trial Featuring Lidocaine And Prilocaine?

Presently, 96 investigations are in progress to analyse the potential of Lidocaine And Prilocaine in treating Bacterial infection, Cervical Syndrome and Multiple Myeloma.

Condition

Clinical Trials

Trial Phases

Local Anaesthesia therapy

0 Actively Recruiting

Lidocaine And Prilocaine Reviews: What are patients saying about Lidocaine And Prilocaine?

5Patient Review

5/10/2022

Lidocaine And Prilocaine for Administration of Local Anesthetic Drug

If you're struggling with Peyronie's, this is a great treatment to try.

3.7Patient Review

12/1/2018

Lidocaine And Prilocaine for Administration of Local Anesthetic Drug

I injured my back and this treatment helped me recover.

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Patient Q&A Section about lidocaine and prilocaine

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is lidocaine and prilocaine used for?

"Lidocaine and prilocaine topical cream is used to numb the skin or genital area before certain medical procedures. It can also help prevent pain from injections, drawing blood from a vein, or minor surgeries like removing warts."

Answered by AI

How long does lidocaine prilocaine cream last?

"The duration of numbness caused by lidocaine/prilocaine depends on the amount applied and the area of the body. It can last for 5 minutes to a few hours."

Answered by AI

What are the side effects of prilocaine and lidocaine?

"If you experience any of the following side effects, discontinue use and contact your doctor: severe burning, stinging, or irritation at the site of application; swelling or redness; sudden dizziness or drowsiness after application; confusion, blurred vision, ringing in your ears; bruising or purple appearance of the skin."

Answered by AI

Does lidocaine prilocaine cream work?

"This medication is used to numb the skin and surrounding area to prevent pain before certain procedures such as inserting a needle, skin grafts, or skin laser surgery."

Answered by AI