High Flow Nasal Cannula for Childhood Asthma
Trial Summary
Do I have to stop taking my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It is best to discuss this with the trial coordinators or your doctor.
What data supports the effectiveness of the treatment High Flow Nasal Cannula for childhood asthma?
Research shows that high flow nasal cannula (HFNC) therapy is used in pediatric wards for children with asthma exacerbations, suggesting it may help improve breathing in these cases. Additionally, HFNC is commonly used in pediatric intensive care for children with breathing difficulties, indicating its potential effectiveness in managing respiratory distress.12345
Is high flow nasal cannula therapy safe for children?
How does the High Flow Nasal Cannula treatment differ from other treatments for childhood asthma?
High Flow Nasal Cannula (HFNC) treatment is unique because it delivers oxygen at a high flow rate through a nasal tube, which can help children with asthma breathe more easily during moderate respiratory failure. Unlike traditional oxygen therapy, HFNC provides a consistent flow of warm, humidified air, which can be more comfortable and effective in emergency situations.910111213
What is the purpose of this trial?
This is a randomized, open-label, 3-armed feasibility trial will examine conventional oxygen therapy (COT) vs high flow nasal cannula at 4L/min flow vs HFNC at 2L/kg/min flow (max 60L/min) in moderate to severe pediatric asthma exacerbations.
Research Team
MicheleE E Smith, MD
Principal Investigator
University of Rochester
Eligibility Criteria
This trial is for children aged 3-17 with a clinical diagnosis of asthma, who are admitted to the PICU on standard asthma treatments and require oxygen therapy. They must have had an exacerbation severe enough to score at least 8 on the PASS after initial emergency treatment.Inclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive randomized oxygen therapy (COT or HFNC) and are monitored for 2 hours in the PICU
Follow-up
Participants are monitored for safety and effectiveness after treatment until hospital discharge
Treatment Details
Interventions
- High Flow Nasal Cannula
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Rochester
Lead Sponsor