Sprintec

Acne Vulgaris, moderate Vulvovaginal atrophy, Hot flashes + 9 more
Treatment
9 FDA approvals
20 Active Studies for Sprintec

What is Sprintec

NorgestimateThe Generic name of this drug
Treatment SummaryEthinylestradiol is a synthetic estrogen hormone first developed in 1938 by two German scientists. This drug was designed to be more easily absorbed when taken orally. It is mainly used as a form of birth control in combination with other hormones. Ethinylestradiol was approved by the FDA in 1943.
Ortho Tri Cyclenis the brand name
image of different drug pills on a surface
Sprintec Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Ortho Tri Cyclen
Norgestimate
1989
113

Approved as Treatment by the FDA

Norgestimate, commonly known as Ortho Tri Cyclen, is approved by the FDA for 9 uses which include Postmenopausal Osteoporosis and severe menopausal vulvovaginal atrophy .
Postmenopausal Osteoporosis
Used to treat Postmenopausal Osteoporosis in combination with Estradiol
severe menopausal vulvovaginal atrophy
Used to treat severe menopausal vulvovaginal atrophy in combination with Estradiol
Oral Contraceptives
Used to treat Oral Contraceptives in combination with Ethinylestradiol
Acne Vulgaris
Used to treat moderate Acne vulgaris in combination with Ethinylestradiol
Osteoporosis, Postmenopausal
Used to treat Postmenopausal Osteoporosis in combination with Estradiol
moderate Vulvovaginal atrophy
Used to treat moderate Vulvovaginal atrophy in combination with Estradiol
Hot flashes
Used to treat Menopause in combination with Estradiol
moderate Menopausal Vasomotor Symptoms
Used to treat moderate Menopausal Vasomotor Symptoms in combination with Estradiol
Menopause
Used to treat severe Vasomotor Symptoms Associated With Menopause in combination with Estradiol

Effectiveness

How Sprintec Affects PatientsEthinylestradiol is a type of synthetic hormone used to reduce the risk of ovulation. It has a long-lasting effect when taken daily, and is generally considered to be a safe drug. Patients should be warned that it can increase the chance of blood clots.
How Sprintec works in the bodyEthinylestradiol is a hormone used in some forms of contraception. It works by reducing the release of hormones that cause ovulation, making it harder for sperm to reach an egg. It can also thicken cervical mucus, making it harder for sperm to move. Ethinylestradiol also reduces the ability of an egg to implant in the uterus and increases a protein that binds to hormones, making them less effective.

When to interrupt dosage

The measure of Sprintec is determined by the indicated affliction, such as Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. The dosage can be found in the table below, contingent upon the technique of administration.
Condition
Dosage
Administration
Polycystic Ovarian Syndrome
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
moderate Vulvovaginal atrophy
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Menopause
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
severe menopausal vulvovaginal atrophy
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Osteoporosis, Postmenopausal
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Oral Contraceptives
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Menorrhagia
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Hirsutism
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
moderate Menopausal Vasomotor Symptoms
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Hot flashes
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Acne Vulgaris
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral
Dysmenorrhea
, 0.25 mg, 0.215 mg, 0.18 mg, 0.09 mg, 0.645 mg
, Kit, Oral, Tablet, Tablet - Oral, Kit - Oral

Warnings

Sprintec has 26 identified contraindications, which means it should not be taken when dealing with any of the conditions specified in the table below.Sprintec Contraindications
Condition
Risk Level
Notes
Breast
Do Not Combine
Breast Cancer
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Pulse Frequency
Do Not Combine
Pulse Frequency
Do Not Combine
Hypersensitivity
Do Not Combine
Venous Thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Metrorrhagia
Do Not Combine
Liver Neoplasms
Do Not Combine
There are 20 known major drug interactions with Sprintec.
Common Sprintec Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Norgestimate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Norgestimate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Norgestimate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Norgestimate.
Astemizole
Major
The metabolism of Astemizole can be increased when combined with Norgestimate.
Sprintec Toxicity & Overdose RiskWomen who overdose on the drug may experience bleeding, nausea, vomiting, breast tenderness, abdominal pain, drowsiness, and fatigue. Treatment for an overdose should include monitoring the patient's potassium and sodium levels as well as signs of metabolic acidosis.
image of a doctor in a lab doing drug, clinical research

Sprintec Novel Uses: Which Conditions Have a Clinical Trial Featuring Sprintec?

There are 38 active studies investigating the utility of Sprintec for Folate supplementation therapy, Premenstrual Dysphoric Disorder and Menopausal symptoms.
Condition
Clinical Trials
Trial Phases
Dysmenorrhea
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting
Osteoporosis, Postmenopausal
0 Actively Recruiting
Oral Contraceptives
0 Actively Recruiting
Menopause
0 Actively Recruiting
Polycystic Ovarian Syndrome
8 Actively Recruiting
Not Applicable, Early Phase 1, Phase 4, Phase 1
moderate Menopausal Vasomotor Symptoms
0 Actively Recruiting
Hirsutism
0 Actively Recruiting
Hot flashes
16 Actively Recruiting
Phase 1, Phase 4, Not Applicable, Early Phase 1, Phase 2
moderate Vulvovaginal atrophy
0 Actively Recruiting
Menorrhagia
0 Actively Recruiting
severe menopausal vulvovaginal atrophy
0 Actively Recruiting

Sprintec Reviews: What are patients saying about Sprintec?

5Patient Review
12/17/2021
Sprintec for Acne
This pill is really good for acne. I'm surprised at how well it works.
4.7Patient Review
11/5/2021
Sprintec for Birth Control
I've been using this birth control for six years now and it's been great! No pregnancy scares, no mood swings or weight gain. The only downside is that I sometimes get muscle pain in my legs and feet.
4.7Patient Review
9/30/2022
Sprintec for Birth Control
I'm really happy with this birth control. Not only did it get rid of my acne, but it also regulates my period so I know exactly when it's coming. Additionally, it made my periods lighter and alleviated many of my period pains. I almost never have cramps anymore!
4.7Patient Review
9/17/2022
Sprintec for Painful Periods
I've been on Sprintec for over 11 years now and it's been great. My skin is amazing, I've never gotten pregnant, and it got rid of my ovarian cysts. Plus, because I take the pill every day (even on the sugar pill days), I don't get a period every month. I can't remember the last time I had one! But be warned: if you miss a pill, your mood will really be affected for the next day or two.
3.3Patient Review
7/2/2022
Sprintec for Birth Control
I started this birth control December 2021. When I started it I was having horrible mood swings and just felt constantly angry. This is typical when I start a new birth control because I have been on a few. The main issue I have with this pill is that it has made me gain almost 10 pounds, despite no change in my diet or workout routine. Other than that it has been fine.
View All Reviews
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about sprintec

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Sprintec a good birth control?

"The average rating for Sprintec from 1000 reviewers is 5.8 out of 10, with 41% having a positive experience and 33% having a negative experience."

Answered by AI

What kind of birth control is Sprintec?

"Sprintec is a combined oral contraceptive (COC) that contains both estrogen and progesterone hormones. It's a monophasic birth control meaning all active tablets contain the same doses of hormones. Sprintec is most effective when taken daily at the same time every day."

Answered by AI

Why was Sprintec discontinued?

"Some important information to remember is that Tri-Lo Sprintec was not taken off the market due to any safety concerns. The reason it was unavailable for a while was because of a patents dispute between the brand manufacturer Janssen Pharmaceuticals and the generic manufacturer Teva Pharmaceuticals. Recently, though, Tri-Lo Sprintec has reappeared."

Answered by AI

Will Sprintec cause weight gain?

"There is a chance that the hormones in Tri-Sprintec can make you want to eat more, but mostly the weight gain is from water retention and not from fat."

Answered by AI

Clinical Trials for Sprintec

Have you considered Sprintec clinical trials? We made a collection of clinical trials featuring Sprintec, we think they might fit your search criteria.
Have you considered Sprintec clinical trials? We made a collection of clinical trials featuring Sprintec, we think they might fit your search criteria.
Image of University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research Laboratory in Aurora, United States.

MitoQ + Exercise for Menopause-Related Vascular Health

50 - 120
Female
Aurora, CO
This trial tests whether combining moderate aerobic exercise with the antioxidant MitoQ can improve blood vessel function in postmenopausal women who lack estrogen. MitoQ aims to reduce oxidative stress and enhance blood flow by improving mitochondrial function. The study will compare the effects of exercise with MitoQ, exercise alone, and MitoQ alone. MitoQ is a mitochondria-targeted antioxidant that has been studied for its potential to enhance exercise-induced muscle adaptations and improve peak power in untrained middle-aged men.
Phase < 1
Waitlist Available
Paid Trial
University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research LaboratoryKerrie L Moreau, PhD
Have you considered Sprintec clinical trials? We made a collection of clinical trials featuring Sprintec, we think they might fit your search criteria.
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