Tri-Estarylla

Birth Control, Acne Vulgaris, Folate supplementation therapy + 5 more
Treatment
1 FDA approval
20 Active Studies for Tri-Estarylla

What is Tri-Estarylla

EthinylestradiolThe Generic name of this drug
Treatment SummaryEthinylestradiol was first invented in 1938 by two scientists, Hans Herloff Inhoffen and Walter Hohlweg, who worked for Schering. They added an ethinyl group to the chemical estradiol, which made it more easily absorbed in the body when taken orally. This drug is now used in many birth control pills and was approved by the FDA in 1943.
LOESTRIN Fe 1.5/30is the brand name
image of different drug pills on a surface
Tri-Estarylla Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
LOESTRIN Fe 1.5/30
Ethinylestradiol
1973
679

Approved as Treatment by the FDA

Ethinylestradiol, also known as LOESTRIN Fe 1.5/30, is approved by the FDA for 1 uses including Birth Control .
Birth Control
Used to treat Contraception in combination with Levonorgestrel

Effectiveness

How Tri-Estarylla Affects PatientsEthinylestradiol is a synthetic hormone used to prevent ovulation and reduce endometrial vascularization. It is taken once per day and is considered to be a safe drug without serious side effects from taking too much. However, it does increase the risk of thrombotic events, so patients should be warned about this risk.
How Tri-Estarylla works in the bodyEthinylestradiol is a synthetic form of the female hormone estrogen. Taking it reduces bone density and suppresses ovulation by stopping hormones from being released. It also thickens the mucus in the cervix and prevents changes in the endometrium that are needed for fertilization. It decreases luteinizing hormone, which decreases vascularity in the uterus, and it increases sex hormone binding globulin.

When to interrupt dosage

The amount of Tri-Estarylla is contingent upon the diagnosed affliction, including Acne Vulgaris, Hormonal Contraception and Folate supplementation therapy. The dosage fluctuates in accordance with the technique of delivery specified in the table underneath.
Condition
Dosage
Administration
Mild to Moderate Acne
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Patient desires oral contraception for birth control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Menopausal Osteoporosis
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Birth Control
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Acne Vulgaris
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Folate supplementation therapy
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Hormonal Contraception
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule
Menopause
, 0.02 mg, 0.0025 mg, 0.03 mg, 0.0035 mg/hour, 0.005 mg, 2.7 mg, 0.035 mg, 0.6 mg, 2.6 mg, 0.05 mg, 0.5 mg, 0.75 mg, 0.025 mg, 0.0015 mg/hour, 0.04 mg, 0.01 mg, 1.0 mg, 0.075 mg, 0.105 mg, 0.07 mg, 0.1 mg, 0.75 mg/[USP'U], 0.0075 mg/hour, 17.4 mg, 0.085 mg, 2.3 mg
, Kit, Tablet - Oral, Oral, Tablet, Kit - Oral, Patch, extended release, Patch, extended release - Transdermal, Transdermal, Insert, extended release, Vaginal, Insert, extended release - Vaginal, Ring - Vaginal, Ring, Tablet, chewable, Tablet, chewable - Oral, Tablet, film coated, Tablet, film coated - Oral, Patch, Patch - Transdermal, Capsule - Oral, Capsule

Warnings

Tri-Estarylla has twenty-six contraindications and should be avoided in cases of the conditions listed in the table below.Tri-Estarylla Contraindications
Condition
Risk Level
Notes
Heavy Smoking
Do Not Combine
Metrorrhagia
Do Not Combine
estrogen-sensitive cancer
Do Not Combine
Thrombophlebitis
Do Not Combine
high risk of venous thrombotic disease
Do Not Combine
history of deep venous thrombosis
Do Not Combine
Pulse Frequency
Do Not Combine
Breast
Do Not Combine
Coronary Artery Disease
Do Not Combine
high risk of arterial thrombotic disease
Do Not Combine
Thromboembolism
Do Not Combine
Coronary Artery Disease (CAD)
Do Not Combine
Hypersensitivity
Do Not Combine
Pulse Frequency
Do Not Combine
Adrenal Insufficiency
Do Not Combine
major surgery with prolonged immobilization
Do Not Combine
Pulse Frequency
Do Not Combine
Severe Hypertension
Do Not Combine
undiagnosed abnormal genital bleeding
Do Not Combine
Breast Cancer
Do Not Combine
Neoplasms, Hepatic
Do Not Combine
Deep Vein Thrombosis
Do Not Combine
Decompensated Cirrhosis
Do Not Combine
Breast
Do Not Combine
Impaired Renal Function
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Ethinylestradiol may interact with Pulse Frequency
There are 20 known major drug interactions with Tri-Estarylla.
Common Tri-Estarylla Drug Interactions
Drug Name
Risk Level
Description
Anastrozole
Major
The therapeutic efficacy of Anastrozole can be decreased when used in combination with Ethinylestradiol.
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Ethinylestradiol.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Ethinylestradiol.
Belinostat
Major
The metabolism of Belinostat can be increased when combined with Ethinylestradiol.
Binimetinib
Major
The metabolism of Binimetinib can be increased when combined with Ethinylestradiol.
Tri-Estarylla Toxicity & Overdose RiskWomen who overdose on birth control pills may experience bleeding, nausea, vomiting, breast tenderness, abdominal pain, drowsiness, and fatigue. Treatment should include monitoring of potassium, sodium, and signs of metabolic acidosis, as well as providing symptomatic and supportive care.
image of a doctor in a lab doing drug, clinical research

Tri-Estarylla Novel Uses: Which Conditions Have a Clinical Trial Featuring Tri-Estarylla?

38 active studies are currently evaluating the potential of Tri-Estarylla in providing Folate supplementation therapy, relieving Premenstrual Dysphoric Disorder and alleviating Menopausal symptoms.
Condition
Clinical Trials
Trial Phases
Birth Control
33 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Early Phase 1
Patient desires oral contraception for birth control
0 Actively Recruiting
Folate supplementation therapy
0 Actively Recruiting
Hormonal Contraception
0 Actively Recruiting
Mild to Moderate Acne
0 Actively Recruiting
Menopausal Osteoporosis
0 Actively Recruiting
Menopause
0 Actively Recruiting
Acne Vulgaris
0 Actively Recruiting

Tri-Estarylla Reviews: What are patients saying about Tri-Estarylla?

5Patient Review
6/10/2022
Tri-Estarylla for Acne
I was a bit apprehensive about taking this birth control pill after reading some of the reviews online; however, I decided to give it a try anyways. I'm glad that I did because it really worked wonders for my acne! My skin cleared up within the first two weeks and my dark scars even started to fade away.
5Patient Review
4/20/2021
Tri-Estarylla for Painful Periods
I've had great results taking this medication for acne, period pain, and other issues. The only downside was some anxiety and nausea when I started taking it, but that went away after a few days.
5Patient Review
4/20/2021
Tri-Estarylla for Painful Periods
I've been taking this medication for a while now and it's been great! My acne has cleared up almost completely, which is amazing. My periods are way lighter and barely hurt at all, which is also awesome. I haven't really noticed any changes in my mood or sex drive, but that's not necessarily a bad thing. The only downside is that I experienced some anxiety and nausea when I first started taking the pill, but I quickly learned that eating something light with it would get rid of that problem.
5Patient Review
6/10/2022
Tri-Estarylla for Acne
I was hesitant to try this birth control pill after reading some of the reviews, but I'm glad I did. It took a week or two for my body to adjust to the hormones, but after that my skin cleared up and my dark scars started disappearing! So far so good.
4.7Patient Review
3/9/2017
Tri-Estarylla for Birth Control
I went back on birth control after a seven year break due to worsening menstrual cramps and heavy bleeding. I found it really helped with those symptoms and didn't have any major issues. The only thing was a bitter taste in my mouth and slight nausea, but since I take the pill before bed, it's not too big of a deal. I'm wondering if the bitter taste is from the pill or something else entirely though, since I haven't seen that mentioned in other reviews.
4.7Patient Review
3/9/2017
Tri-Estarylla for Birth Control
I went back on birth control after seven years due to the return of very painful cramps and heavy bleeding. I was really pleased with how well this medication worked for me in terms of reducing those symptoms. The only downside is that I noticed a bitter taste in my mouth and felt slightly nauseous. Since I take the pill before bed, though, it didn't bother me too much. Still, I'm curious if the taste is from the pill or something else entirely.
4Patient Review
6/14/2017
Tri-Estarylla for Birth Control
I've been using Tri-Estarylla for just under two weeks now and, so far, I'm really pleased. All the reviews I read before starting this treatment were pretty negative but, in my experience, it's been great. I was already on another generic birth control with the same ingredients, so switching over was a breeze. As for effectiveness, I'll have to wait and see if I get pregnant or not; however, I haven't had any breakthrough bleeding like I did with my other pills which is awesome.
4Patient Review
6/14/2017
Tri-Estarylla for Birth Control
I've been using Tri-Estarylla for just under two weeks and have had no issues. I was hesitant at first because of all the negative reviews, but it's been fine. I switched over from another generic birth control with the same ingredients, so the transition was easy. I gave effectiveness only 2 stars because time will tell if it actually prevents pregnancy. Another thing to note is that I haven't experienced any breakthrough bleeding, which was a problem with my other pills.
3.7Patient Review
6/6/2017
Tri-Estarylla for Birth Control
I was previously on Tri-Sprintec but switched pharmacies and was given this birth control instead. I absolutely hate it. I've only been on it for a month and a half, and I've already experienced mood swings and depression that I initially thought were just me going through something, but now realize are likely caused by this birth control. I never want to use this again. If you can help it, stay away from this medication.
3.7Patient Review
6/6/2017
Tri-Estarylla for Birth Control
I was on Tri-Sprintec but changed pharmacies and was given this birth control and I hate it. I have only been on it for maybe a month and a half, and I have been having mood swings and depression that at first I thought were just something temporary that I was going through, but now realize are caused by this birth control. I do not want to use this ever again. If you can, stay away from this birth control.
2Patient Review
9/14/2018
Tri-Estarylla for Birth Control
I took this pill for too long and it changed me into a person I didn't recognize. I became apathetic to sex, quick to anger, and my relationship was really suffering because of it. Thankfully, I've been off the pill for a month now and feeling more like myself every day. If you're experiencing any negative effects, stop taking the pill immediately!
2Patient Review
9/5/2021
Tri-Estarylla for Abnormally Long or Heavy Periods
While this medication did help with my heavy menstrual flow, the side effects were incredibly dangerous. I experienced three pulmonary embolisms and terrible acne while taking this medication. Thankfully, I stopped taking it immediately and have feeling much better since then.
2Patient Review
4/15/2021
Tri-Estarylla for Acne
At first, this medication worked well for me; however, I stopped taking it when my pharmacy switched to a different brand. Recently, I decided to give the original brand another try - big mistake. Not only did my acne come back worse than before, but I also experienced breakouts every day. This pill was a total nightmare and I would not recommend it to anyone struggling with acne.
2Patient Review
7/6/2017
Tri-Estarylla for Birth Control
I've been on this medication for two weeks and I really don't like it. I'm constantly moody and crying over nothing. I would not recommend it to others.
2Patient Review
7/17/2017
Tri-Estarylla for Abnormally Long or Heavy Periods
Unfortunately, this birth control didn't work well for me. I had my period for four months straight and saw no change in my acne or weight (I gained 12 pounds).
2Patient Review
7/6/2017
Tri-Estarylla for Birth Control
I've been on this medication for two weeks and, unfortunately, I can't stand it. I'm already looking into switching birth controls because of how moody and emotional this has made me.
2Patient Review
4/15/2021
Tri-Estarylla for Acne
At first, this medication was effective; however, I stopped taking it when my pharmacy switched to a different brand. Recently, I decided to give the original brand another try—big mistake. Not only did my acne not improve, but it actually got worse. Every day, I would wake up with 3-4 new pimples. This made me feel very insecure and self-conscious, to the point where I didn't want to leave the house without makeup. In short: do not bother with this pill if you're hoping to clear your skin.
2Patient Review
9/5/2021
Tri-Estarylla for Abnormally Long or Heavy Periods
I had three pulmonary embolisms from this medication and it was honestly a nightmare. I also experienced terrible acne and mood swings that were really unlike anything else I've ever felt before. Needless to say, I stopped taking the medication immediately and feel much better now.
2Patient Review
7/17/2017
Tri-Estarylla for Abnormally Long or Heavy Periods
I had my period for 4 months straight on this BC, my acne didn't clear up at all, and I gained 12 pounds.
2Patient Review
9/14/2018
Tri-Estarylla for Birth Control
I took this pill for far too long, and it nearly destroyed my life. It killed my sex drive, made me depressed and irritable, and I constantly fought with my partner. If you're experiencing any of these effects, stop taking the pill immediately!
1.7Patient Review
1/22/2017
Tri-Estarylla for Disease of Ovaries with Cysts
I have only been on this medication for a week, and I already hate it. I've spotted the entire time, with an incredibly foul smell. I've also had headaches all week that have made me feel nauseous and exhausted. I usually go to bed around 11:30 or 12, but since being on this pill I haven't been able to fall asleep until much later. As a result, I feel useless and depressed and have no energy. This pill has done nothing but cause problems so far, and I'm done with it.
1.7Patient Review
1/22/2017
Tri-Estarylla for Disease of Ovaries with Cysts
I have only been on this medication for a week, and I already hate it. I've been spotting the entire time, and it smells terrible. I've also had headaches all week that have gotten so bad they've made me feel dizzy and nauseous. Some nights I'm so tired but can't fall asleep, which is really frustrating. Overall, I just feel really exhausted and hopeless while taking this pill, and I don't think it's worth it.
1.3Patient Review
2/23/2018
Tri-Estarylla for Acne
I would not recommend this pill to anyone. I've been on it for a few months now in an effort to improve my acne and regulate my periods, but there have only been negative side effects. My emotional state has deteriorated noticeably since starting this medication, and I believe it's the root cause.
1.3Patient Review
2/23/2018
Tri-Estarylla for Acne
I would not recommend this pill to anyone. I've been on it for a few months in an effort to combat my acne, as well as use it for birth control and lighter periods. However, my acne hasn't cleared up at all, and I think the pill might be responsible for making me an emotional wreck these last few months.
1Patient Review
12/2/2020
Tri-Estarylla for Birth Control
My experience with this medication has been terrible. I was switched to this from Sprintec and have been on a never-ending period that is thick, brown, and very abnormal. In addition, my face has broken out horribly and itches constantly. I would gladly pay out of pocket before continuing to take this medication. Do yourself a favor and avoid this medicine if at all possible.
1Patient Review
12/2/2020
Tri-Estarylla for Birth Control
I had a terrible experience with this medication. I was constantly on my period and it was extremely heavy, thick, and brown. My face also broke out horribly and itched all the time. I would much rather pay out of pocket for a different medication than continue taking this one.

Patient Q&A Section about tri-estarylla

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Tri-Estarylla generic for?

"Tri-Estarylla is a brand-name women's birth control pill that contains ethinyl estradiol and norgestimate. Tri-Estarylla, a generic version of Janssen's Ortho Tri-Cyclen, is a triphasic birth control pill. This means that three different doses of the active ingredients are taken over the 28-day birth control cycle."

Answered by AI

Is Tri-Estarylla a good birth control?

"Tri-Estarylla has been given an average rating of 4.3 out of 10 by reviewers, based on a total of 59 ratings for the treatment of Birth control. Of those reviewers, 32% reported having a positive experience, while 56% reported having a negative experience."

Answered by AI

Does Tri-Estarylla cause weight gain?

"Fatigue.

Pigmentation changes, irregular bleeding, nausea, weight gain, and fatigue may be signs of hormonal imbalance."

Answered by AI

Does Estarylla have side effects?

"The following side effects may occur: nausea, vomiting, headache, bloating, breast tenderness, swelling of ankles/feet (fluid retention), or weight change. Vaginal bleeding between periods (spotting) or missed/irregular periods may occur, especially during the first few months of use."

Answered by AI

Clinical Trials for Tri-Estarylla

Have you considered Tri-Estarylla clinical trials? We made a collection of clinical trials featuring Tri-Estarylla, we think they might fit your search criteria.
Have you considered Tri-Estarylla clinical trials? We made a collection of clinical trials featuring Tri-Estarylla, we think they might fit your search criteria.
Have you considered Tri-Estarylla clinical trials? We made a collection of clinical trials featuring Tri-Estarylla, we think they might fit your search criteria.