In most cases it is not clear why lymphoma develops, and the exact causes remain unproven. It is likely that there are many different factors involved, and that each of these can contribute to a developing disease. Lymphoma may be caused by viruses or viruses may cause lymphoma by triggering mutations in normal cells. Most lymphomas are probably multifactorial. However, several agents are known or suspected of being causes, including cancer-causing bacteria such as "Mycobacterium avium" complex (MAC) and Epstein-Barr virus, which have a role in development and progression of some lymphomas. Some lymphomas are due to genetic syndromes.
We conclude that in a selected group of patients with non-Hodgkin's lymphoma, chemotherapy can induce very durable complete remissions. This approach to cure lymphoma still requires prospective trials and large prospective registries.
Lymphoma is a cancer that starts in white blood cells (lymphocytes) and can form anywhere in the body. Patients frequently have a history of exposure to a common virus in childhood, and then develop a lymphoma five to 20 years later. The most common form is non-Hodgkin Lymphoma, which consists of a wide range of types of lymphoma, including T-cells and M-cells. Lymphoma has also been called "glandular lymphoma".\n
Lymphoma patients will present with cough, night sweats, and anorexia. Rarely, tumour can be identified as an enlarged lymph node. For patients with no obvious signs or symptoms of lymphoma, further investigations are not necessary.
Although many patients with lymphoma will respond to one or more of the treatment options described below, there is considerable variation in outcomes, response, and tolerability of treatment. Patients with less aggressive lymphoma may have long-term survival after treatment. Lymphoma is still a devastating disease, and innovative, experimental therapies (e.g., immunotherapy) are being pursued in an effort to find more effective ways to treat lymphoma.
Data from a recent study corroborate those of two similar previous studies on the general population. No statistical differences were noted for physical QOL or psychological QOL improvements in all 3 studies. Data from a recent study strongly support the need for treatment to improve physical functioning and psychological well-being for people with lymphoma.
In spite of the availability of highly effective therapies, there are still significant treatment-related problems, including those related to the development of drug-resistance, toxicity and patient-specific issues. These continue to present a challenge for the evolving treatment of cancer. New discoveries may lead to the discovery of improved and simplified treatment regimens for cancer patients in the future.
“There is no evidence that a single type of treatment is more helpful against the other types of lymphoma and their subtypes.” “The chemotherapy and the radiotherapy do not kill the cancer in the same way and they have been found to work better as an alternate or in combination.” “If the treatment for one form of the cancer is a drug, and the drug has been found not to work against the other cancer, then it is not in the best interest of the person if she is taken off the other therapy.” “Sometimes the cancer stays where it is and is not put under treatment until after a very short period of time.
This is quite often the case. The average age of time from diagnosis is 5 years but ranges from 3 to 12 years. Even though most of the time there is a good prognosis lymphoma is a very difficult to treat and can become very bad. But they can be cured or at least not get worse. Lymphoma treatment is usually made of chemotherapy or surgical manipulation plus radiotherapy, the goal being that the cancer is removed from your body and stays there. This way when you get diagnosed with the cancer you are already
Patients treated with radiation for any cause can experience an increase in temporary side effects such as skin rashes. A decrease in their immune system’s ability to fight cancer can result from the use of steroids. The drugs do not always have a lot of side effects for long-term use.\n\n- Oncolytic virus therapy"
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One year the majority of lymphomas develop in adulthood. The overall median age of development is about 52 years; the male:female incidence ratio is 1.6:1 and about 30% of the lymphomas occurred in the early twenties. The most common types of lymphoma occurring in adulthood are diffuse large B-cell lymphoma, mantle cell lymphoma, small cell lymphoma and splenic marginal zone lymphoma. The incidence of these is in contrast to childhood. In the early twentieth century Hodgkins disease was a childhood disease occurring mainly in children under 15 years of age. Recently the incidence rate of childhood non-Hodgkins lymphoma has been increasing with more teenagers afflicted with this disease.