Supine Positioning During Delayed Cord Clamping for Delayed Cord Clamping

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Johns Hopkins University, Baltimore, MD
Delayed Cord Clamping
Prone Positioning - Procedure
Eligibility
18 - 65
Female
What conditions do you have?
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Study Summary

Delayed cord clamping is a routine technique used in the delivery room. The baby remains attached to the umbilical cord and placenta for 30-60 seconds after birth to allow for maximal transfer of oxygen and blood to the newborn. This study seeks to determine the best position (on the back versus on the belly) for the newborn during the 30-60 seconds of delayed cord clamping.

Treatment Effectiveness

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: 30-60 seconds immediately after birth of the newborn

30-60 seconds immediately after birth of the newborn
Number of pre-term neonates that require endotracheal intubation

Trial Safety

Trial Design

2 Treatment Groups

Supine Positioning During Delayed Cord Clamping
1 of 2
Prone Positioning During Delayed Cord Clamping
1 of 2
Active Control

260 Total Participants · 2 Treatment Groups

Primary Treatment: Supine Positioning During Delayed Cord Clamping · No Placebo Group · N/A

Supine Positioning During Delayed Cord ClampingActiveComparator Group · 2 Interventions: Prone Positioning, Supine Positioning · Intervention Types: Procedure, Procedure
Prone Positioning During Delayed Cord ClampingActiveComparator Group · 2 Interventions: Prone Positioning, Supine Positioning · Intervention Types: Procedure, Procedure

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 30-60 seconds immediately after birth of the newborn
Closest Location: Johns Hopkins University · Baltimore, MD
Photo of Johns Hopkins University 1Photo of Johns Hopkins University 2Photo of Johns Hopkins University 3
1997First Recorded Clinical Trial
1 TrialsResearching Delayed Cord Clamping
690 CompletedClinical Trials

Who is running the clinical trial?

West Penn Allegheny Health SystemOTHER
33 Previous Clinical Trials
2,716 Total Patients Enrolled
Johns Hopkins UniversityLead Sponsor
2,033 Previous Clinical Trials
30,782,139 Total Patients Enrolled
Mara Rosner, MDPrincipal InvestigatorJohns Hopkins University

Eligibility Criteria

Age 18 - 65 · Female Participants · 6 Total Inclusion Criteria

Mark “yes” if the following statements are true for you:
You are a fetus without major anomalies or known genetic condition that could impact respiratory status or need for intubation at birth.
You are pregnant with a singleton or twin pregnancy.
Patient is able to understand study procedures and is willing and able to consent.
You are between 25 and 29 weeks' gestational age.

About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 9th, 2021

Last Reviewed: August 12th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.