Ivermectin

Malaria, Myiasis, Gnathostomiasis + 10 more
Treatment
10 Active Studies for Ivermectin

What is Ivermectin

IvermectinThe Generic name of this drug
Treatment SummaryIvermectin is a drug used to treat worm infections and head lice infestations in humans. It is derived from a bacteria called Streptomyces avermitilis. Recently, ivermectin has been studied for its potential to prevent or treat symptoms of the COVID-19 virus. While some studies have been conducted, more research needs to be done before it can be used safely and effectively for this purpose. Until then, people should avoid using ivermectin for COVID-19 and rely on other approved treatments, such as vaccines.
Stromectolis the brand name
Ivermectin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Stromectol
Ivermectin
1996
22

Effectiveness

How Ivermectin Affects PatientsIvermectin is a medication used to treat parasites. It is made from a type of sugar molecule, called a pentacyclic sixteen-membered lactone, which comes from a particular type of bacteria found in soil. Ivermectin is a very powerful and effective treatment for parasites.
How Ivermectin works in the bodyIvermectin works by attaching to certain channels in parasites and increasing their permeability. This makes it difficult for the parasite to move and eventually kills it. Ivermectin may also act as a stimulant for the neurotransmitter GABA, which can disrupt communication between nerve cells in the brain and spinal cord. Finally, Ivermectin may interfere with the development of parasite eggs and stop them from being released from infected female worms.

When to interrupt dosage

The measure of Ivermectin is dependent upon the diagnosed condition, such as Enterobiasis, Strongyloidiasis caused by Strongyloides Stercoralis Infection and Malaria. The dose can be found in the table below, contingent upon the mode of administration (e.g. Gel - Topical or Lotion - Topical).
Condition
Dosage
Administration
Enterobiasis
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Strongyloidiasis caused by Strongyloides Stercoralis Infection
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Malaria
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Gnathostomiasis
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Communicable Diseases
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Myiasis
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Filariasis
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Demodex Infestation
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Head
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Ascariasis
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Rosacea
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Trichuriasis
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical
Scabies
0.00585 mg/mg, , 1.0 %, 0.005 mg/mg, 0.01 mg/mg, 3.0 mg, 6.0 mg
Gel - Topical, Lotion - Topical, , Cream, Tablet - Oral, Topical, Tablet, Gel, Lotion, Oral, Cream - Topical

Warnings

Ivermectin has one contraindication and should be avoided when experiencing the conditions present in the table below.Ivermectin Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Ivermectin may interact with Toxoplasma Infections
There are 20 known major drug interactions with Ivermectin.
Common Ivermectin Drug Interactions
Drug Name
Risk Level
Description
Revefenacin
Major
Ivermectin may decrease the excretion rate of Revefenacin which could result in a higher serum level.
Vazegepant
Major
The serum concentration of Zavegepant can be increased when it is combined with Ivermectin.
Ambrisentan
Minor
The excretion of Ambrisentan can be decreased when combined with Ivermectin.
Asunaprevir
Minor
The excretion of Asunaprevir can be decreased when combined with Ivermectin.
Atrasentan
Minor
The excretion of Atrasentan can be decreased when combined with Ivermectin.
Ivermectin Toxicity & Overdose RiskWhen used correctly, ivermectin lotions and creams are unlikely to cause serious harm. If too much ivermectin is ingested, inhaled, injected, or absorbed through the skin, people may experience side effects such as rash, swelling, headaches, dizziness, weakness, nausea, vomiting, and diarrhea. Less common reactions may include seizures, lack of coordination, difficulty breathing, stomach pain, tingling, hives, and skin irritation. Taking too much ivermectin can be fatal for mice and rats. If overdose is suspected, supportive treatments like fluids and electrolytes may be used,

Ivermectin Novel Uses: Which Conditions Have a Clinical Trial Featuring Ivermectin?

Currently, 8 active studies are investigating the possibility of using Ivermectin to ameliorate Rosacea, Head Lice, and Strongyloidiasis caused by Strongyloides Stercoralis Infection.
Condition
Clinical Trials
Trial Phases
Rosacea
8 Actively Recruiting
Not Applicable, Early Phase 1, Phase 2, Phase 3, Phase 4, Phase 1
Gnathostomiasis
0 Actively Recruiting
Strongyloidiasis caused by Strongyloides Stercoralis Infection
0 Actively Recruiting
Head
0 Actively Recruiting
Myiasis
0 Actively Recruiting
Trichuriasis
1 Actively Recruiting
Phase 1
Demodex Infestation
1 Actively Recruiting
Phase 2
Filariasis
0 Actively Recruiting
Scabies
0 Actively Recruiting
Enterobiasis
0 Actively Recruiting
Ascariasis
0 Actively Recruiting
Malaria
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting

Ivermectin Reviews: What are patients saying about Ivermectin?

5Patient Review
6/5/2021
Ivermectin for Presence of Head Lice
This treatment is effective and I would recommend it to others.
4.3Patient Review
1/21/2018
Ivermectin for Intestinal Infection caused by the Roundworm Strongyloides
This treatment is good at alleviating pain.
3.3Patient Review
4/23/2021
Ivermectin for Disease caused by the Worm Onchocerca Volvulus
This medication effectively killed the scabies, but I experienced some heart palpitations as a result of taking it with other medications.
2.7Patient Review
6/5/2015
Ivermectin for Intestinal Infection caused by the Roundworm Strongyloides
Ivermectin, when taken in 21 mg dosages and on five different occasions does provide some relief for a few days; however, the infection always comes back. I'm currently trying garlic as an alternative treatment, which gives me similar levels of relief but is harder to stomach.

Patient Q&A Section about ivermectin

Who should get Paxlovid?

"The FDA has authorized Paxlovid for people aged 12 and over who weigh at least 88 pounds. However, in order to qualify for a prescription, you must also have had a positive COVID-19 test result and be at high risk of developing severe COVID-19." - Anonymous Online Contributor

Unverified Answer

Is there an emergency use authorization for ivermectin in the U.S. to prevent or treat COVID-19?

"The FDA has created a special emergency program called the Coronavirus Treatment Acceleration Program (CTAP) to speed up the development and review of potential therapies for the virus." - Anonymous Online Contributor

Unverified Answer

What is the name of the drug that helps treat COVID-19?

"Paxlovid, a combination of the generic drugs nirmatrelvir and ritonavir, has been shown to clear benefit and prevent hospitalization and death in people who are at high risk for COVID-19. It is important to note that Paxlovid is not the only pill available to treat COVID-19." - Anonymous Online Contributor

Unverified Answer

How effective is Paxlovid?

"The data showed that unvaccinated participants who were given Paxlovid were 89% less likely to develop severe illness and death compared to trial participants who received a placebo." - Anonymous Online Contributor

Unverified Answer

How long is a person with COVID-19 contagious?

"The CDC has said that people who have mild to moderate symptoms of Covid-19 are likely only to be infectious for 10 days after their symptoms first appear. For people with more severe symptoms, the CDC believes that they are likely to be infectious for 20 days." - Anonymous Online Contributor

Unverified Answer

What is COVID rebound?

"The phrase "COVID rebound" is used by the CDC to describe a situation where someone who has recovered from the virus suddenly experiences a return of symptoms or tests positive for the virus again. This usually happens 2-8 days after the initial recovery." - Anonymous Online Contributor

Unverified Answer

What are the best treatments for COVID-19?

"-Pediatric patients are eligible for treatment with Veklury (remdesivir) if they have positive results of direct SARS-CoV-2 viral testing and are hospitalized with severe COVID-19.

Paxlovid and Veklury are the preferred treatments for eligible adults and children who are at high risk for severe COVID-19 and have positive results for direct SARS-CoV-2 viral testing. Children are eligible for treatment with Veklury if they are hospitalized with severe COVID-19 and have direct SARS-CoV-2 viral testing." - Anonymous Online Contributor

Unverified Answer

How many times can a person get COVID-19?

"There is a possibility that you can contract COVID-19 more than once. It is possible to get the virus many times, and you should not assume that you are immune just because you have had it before." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Clinical Trials for Ivermectin

Have you considered Ivermectin clinical trials? We made a collection of clinical trials featuring Ivermectin, we think they might fit your search criteria.
Have you considered Ivermectin clinical trials? We made a collection of clinical trials featuring Ivermectin, we think they might fit your search criteria.
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