Invega

Schizophrenia, Schizoaffective Disorder, Antidepressants + 3 more
Treatment
20 Active Studies for Invega

What is Invega

PaliperidoneThe Generic name of this drug
Treatment SummaryPaliperidone is a drug used to treat schizophrenia. It works by blocking signals from dopamine, serotonin, and other neurotransmitters in the brain. Paliperidone was approved by the FDA in 2006 and is available in tablet form or as an injection given once a month or every three months.
Invegais the brand name
image of different drug pills on a surface
Invega Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Invega
Paliperidone
2006
81

Effectiveness

How Invega Affects PatientsPaliperidone is an antipsychotic medication developed by Janssen Pharmaceutica. It is made from the same active ingredient as the older antipsychotic risperidone. How it works is still not clear, but it is thought to work in a similar way to risperidone.
How Invega works in the bodyPaliperidone is the active part of a drug used to treat schizophrenia. We don't know exactly how it works, but research suggests that it blocks the effects of dopamine and serotonin on the brain. Blocking these chemicals helps to reduce the symptoms of schizophrenia.

When to interrupt dosage

The proposed dosage of Invega is contingent upon the determined condition, like Therapeutic procedure, Schizophrenia and Mood stabilizing agents. The amount of dosage is subject to the technique of delivery listed in the table beneath.
Condition
Dosage
Administration
Schizophrenia
, 6.0 mg, 3.0 mg, 1.5 mg, 9.0 mg, 75.0 mg, 100.0 mg, 50.0 mg, 150.0 mg, 12.0 mg, 25.0 mg, 175.0 mg, 263.0 mg, 350.0 mg, 525.0 mg, 390.0 mg/mL, 780.0 mg/mL, 1170.0 mg/mL, 156.0 mg/mL, 234.0 mg/mL, 2730.0 mg/mL, 410.0 mg/mL, 546.0 mg/mL, 819.0 mg/mL, 750.0 mg/mL, 150.0 mg/mL, 1.5 mg/mg, 100.0 mg/mL, 500.0 mg/mL, 250.0 mg/mL, 263.0 mg/mL, 350.0 mg/mL, 525.0 mg/mL, 1750.0 mg/mL, 700.0 mg/mL, 1000.0 mg/mL, 1092.0 mg/mL, 1560.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release - Intramuscular, Intramuscular, Suspension, extended release, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Injection, Injection - Intramuscular
Schizoaffective Disorder
, 6.0 mg, 3.0 mg, 1.5 mg, 9.0 mg, 75.0 mg, 100.0 mg, 50.0 mg, 150.0 mg, 12.0 mg, 25.0 mg, 175.0 mg, 263.0 mg, 350.0 mg, 525.0 mg, 390.0 mg/mL, 780.0 mg/mL, 1170.0 mg/mL, 156.0 mg/mL, 234.0 mg/mL, 2730.0 mg/mL, 410.0 mg/mL, 546.0 mg/mL, 819.0 mg/mL, 750.0 mg/mL, 150.0 mg/mL, 1.5 mg/mg, 100.0 mg/mL, 500.0 mg/mL, 250.0 mg/mL, 263.0 mg/mL, 350.0 mg/mL, 525.0 mg/mL, 1750.0 mg/mL, 700.0 mg/mL, 1000.0 mg/mL, 1092.0 mg/mL, 1560.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release - Intramuscular, Intramuscular, Suspension, extended release, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Injection, Injection - Intramuscular
Mood stabilizing agents
, 6.0 mg, 3.0 mg, 1.5 mg, 9.0 mg, 75.0 mg, 100.0 mg, 50.0 mg, 150.0 mg, 12.0 mg, 25.0 mg, 175.0 mg, 263.0 mg, 350.0 mg, 525.0 mg, 390.0 mg/mL, 780.0 mg/mL, 1170.0 mg/mL, 156.0 mg/mL, 234.0 mg/mL, 2730.0 mg/mL, 410.0 mg/mL, 546.0 mg/mL, 819.0 mg/mL, 750.0 mg/mL, 150.0 mg/mL, 1.5 mg/mg, 100.0 mg/mL, 500.0 mg/mL, 250.0 mg/mL, 263.0 mg/mL, 350.0 mg/mL, 525.0 mg/mL, 1750.0 mg/mL, 700.0 mg/mL, 1000.0 mg/mL, 1092.0 mg/mL, 1560.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release - Intramuscular, Intramuscular, Suspension, extended release, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Injection, Injection - Intramuscular
Antidepressants
, 6.0 mg, 3.0 mg, 1.5 mg, 9.0 mg, 75.0 mg, 100.0 mg, 50.0 mg, 150.0 mg, 12.0 mg, 25.0 mg, 175.0 mg, 263.0 mg, 350.0 mg, 525.0 mg, 390.0 mg/mL, 780.0 mg/mL, 1170.0 mg/mL, 156.0 mg/mL, 234.0 mg/mL, 2730.0 mg/mL, 410.0 mg/mL, 546.0 mg/mL, 819.0 mg/mL, 750.0 mg/mL, 150.0 mg/mL, 1.5 mg/mg, 100.0 mg/mL, 500.0 mg/mL, 250.0 mg/mL, 263.0 mg/mL, 350.0 mg/mL, 525.0 mg/mL, 1750.0 mg/mL, 700.0 mg/mL, 1000.0 mg/mL, 1092.0 mg/mL, 1560.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release - Intramuscular, Intramuscular, Suspension, extended release, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Injection, Injection - Intramuscular
Therapeutic procedure
, 6.0 mg, 3.0 mg, 1.5 mg, 9.0 mg, 75.0 mg, 100.0 mg, 50.0 mg, 150.0 mg, 12.0 mg, 25.0 mg, 175.0 mg, 263.0 mg, 350.0 mg, 525.0 mg, 390.0 mg/mL, 780.0 mg/mL, 1170.0 mg/mL, 156.0 mg/mL, 234.0 mg/mL, 2730.0 mg/mL, 410.0 mg/mL, 546.0 mg/mL, 819.0 mg/mL, 750.0 mg/mL, 150.0 mg/mL, 1.5 mg/mg, 100.0 mg/mL, 500.0 mg/mL, 250.0 mg/mL, 263.0 mg/mL, 350.0 mg/mL, 525.0 mg/mL, 1750.0 mg/mL, 700.0 mg/mL, 1000.0 mg/mL, 1092.0 mg/mL, 1560.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release - Intramuscular, Intramuscular, Suspension, extended release, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Injection, Injection - Intramuscular
Therapeutic procedure
, 6.0 mg, 3.0 mg, 1.5 mg, 9.0 mg, 75.0 mg, 100.0 mg, 50.0 mg, 150.0 mg, 12.0 mg, 25.0 mg, 175.0 mg, 263.0 mg, 350.0 mg, 525.0 mg, 390.0 mg/mL, 780.0 mg/mL, 1170.0 mg/mL, 156.0 mg/mL, 234.0 mg/mL, 2730.0 mg/mL, 410.0 mg/mL, 546.0 mg/mL, 819.0 mg/mL, 750.0 mg/mL, 150.0 mg/mL, 1.5 mg/mg, 100.0 mg/mL, 500.0 mg/mL, 250.0 mg/mL, 263.0 mg/mL, 350.0 mg/mL, 525.0 mg/mL, 1750.0 mg/mL, 700.0 mg/mL, 1000.0 mg/mL, 1092.0 mg/mL, 1560.0 mg/mL
, Oral, Tablet, extended release, Tablet, extended release - Oral, Suspension, extended release - Intramuscular, Intramuscular, Suspension, extended release, Injection, suspension, extended release, Injection, suspension, extended release - Intramuscular, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Injection, Injection - Intramuscular

Warnings

There are 20 known major drug interactions with Invega.
Common Invega Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The serum concentration of Abemaciclib can be increased when it is combined with Paliperidone.
Acepromazine
Major
Paliperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Alfuzosin
Major
Paliperidone may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Paliperidone may increase the antipsychotic activities of Amisulpride.
Aripiprazole lauroxil
Major
Paliperidone may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Invega Toxicity & Overdose RiskOverdosing on this drug may lead to confusion, seizures, or spasms of the head and neck, which could increase the risk of inhaling vomit if emesis is induced.
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Invega Novel Uses: Which Conditions Have a Clinical Trial Featuring Invega?

221 active clinical trials are currently in progress to evaluate the potential of Invega for Schizoaffective Disorder, Schizophrenia and Mood stabilizing agent therapy.
Condition
Clinical Trials
Trial Phases
Schizophrenia
108 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 2, Phase 1
Therapeutic procedure
0 Actively Recruiting
Mood stabilizing agents
0 Actively Recruiting
Schizoaffective Disorder
47 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Early Phase 1, Phase 3
Antidepressants
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting

Invega Reviews: What are patients saying about Invega?

5Patient Review
5/9/2019
Invega for Bipolar I Disorder with Most Recent Episode Mixed
Though it effectively treats mania, I hope to stop taking this medication soon because of the side effects that come with it.
5Patient Review
4/14/2020
Invega for Schizophrenia
This medication has been effective in keeping my voices at bay. I found coupons for it online that made it much more affordable.
5Patient Review
8/11/2022
Invega for Bipolar Disorder in Remission
I receive a monthly injection of Invega for bipolar disorder with psychosis, and it has been excellent for me! I can think more clearly and feel more positive about myself. As for the weight gain, I find myself hungry every couple hours, but I eat healthy and drink a lot of water. Great medication that has changed my life.
4Patient Review
8/7/2015
Invega for Schizophrenia
The weight gain is really the only downside to this medication; other than that, it's quite good.
4Patient Review
1/18/2022
Invega for Schizophrenia With Mood Changes
Invegga successfully cured my delusions and psychotic behavior. However, I have noted several side effects including lack of motivation, excessive sleeping, increased appetite, and weight gain. Additionally, I experience anxiety and dizziness frequently.
View All Reviews
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Patient Q&A Section about invega

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What does INVEGA do to the brain?

"Invega is designed to correct the imbalance of certain neurotransmitters in the brain, specifically dopamine and serotonin. Its chemical structure is similar to Risperdal's, but it often produces fewer extrapyramidal side effects (tremor, stiffness, etc.)."

Answered by AI

How does INVEGA make you feel?

"Avoid becoming overheated or dehydrated in hot weather or during exercise.

If you are taking INVEGA®, you may feel dizzy, sleepy, or less alert. Be careful when driving or operating machinery until you know how this medicine will affect you. You may be more sensitive to heat while taking this medication. Avoid overheating or becoming dehydrated in hot weather or during exercise."

Answered by AI

What is the drug INVEGA used for?

"Paliperidone is a medication that works in the brain by restoring the balance of dopamine and serotonin. This improves thinking, mood, and behavior in people with schizophrenia and schizoaffective disorder."

Answered by AI

What does INVEGA do to a normal person?

"Invega is a medication that helps restore the balance of certain neurotransmitters in the brain. Invega specifically affects dopamine and serotonin. It is similar to Risperdal in how it works, but often has fewer side effects."

Answered by AI

What are the side effects of taking INVEGA?

"The following side effects may occur: drowsiness, dizziness, lightheadedness, drooling, stomach/abdominal pain, weight gain, or tiredness. If you experience any of these side effects, talk to your doctor. Dizziness and lightheadedness can make you more likely to fall. To avoid falling, get up slowly when you stand up from a sitting or lying position."

Answered by AI

Clinical Trials for Invega

Have you considered Invega clinical trials? We made a collection of clinical trials featuring Invega, we think they might fit your search criteria.
Have you considered Invega clinical trials? We made a collection of clinical trials featuring Invega, we think they might fit your search criteria.
Have you considered Invega clinical trials? We made a collection of clinical trials featuring Invega, we think they might fit your search criteria.
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