Ibu

Insomnia, Catarrh, Chronic Pain + 33 more

Treatment

13 FDA approvals

20 Active Studies for Ibu

What is Ibu

Ibuprofen

The Generic name of this drug

Treatment Summary

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) derived from propionic acid and it is considered the first of the propionics.[A39074] The formula of ibuprofen is 2-(4-isobutylphenyl) propionic acid and its initial development was in 1960 while researching for a safer alternative for aspirin.[A39075] Ibuprofen was finally patented in 1961 and this drug was first launched against rheumatoid arthritis in the UK in 1969 and USA in 1974. It was the first available over-the-counter NSAID.[A39076] On the available products, ibuprofen is administered as a racemic mixture. Once administered, the R-enantiomer undergoes extensive interconversion to the S-enantiomer _in vivo_ by the activity of the alpha-methylacyl-CoA racemase. In particular, it is generally proposed that the S-enantiomer is capable of eliciting stronger pharmacological activity than the R-enantiomer.[A39194]

Motrin

is the brand name

image of different drug pills on a surface

Ibu Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Motrin

Ibuprofen

1974

2460

Approved as Treatment by the FDA

Ibuprofen, also called Motrin, is approved by the FDA for 13 uses including Acute Pain and Dysmenorrhea .

Acute Pain

Used to treat Pain, Acute in combination with Oxycodone

Dysmenorrhea

Mild pain

Gastric Ulcer

Used to treat Gastric Ulcer in combination with Famotidine

Rheumatoid Arthritis

Used to treat Rheumatoid Arthritis in combination with Famotidine

Stomach Ulcer

Used to treat Gastric Ulcer in combination with Famotidine

Pain, Acute

Used to treat Pain, Acute in combination with Oxycodone

Osteoarthritis (OA)

Used to treat Osteoarthritis (OA) in combination with Famotidine

Migraine

Osteoarthritis

Used to treat Osteoarthritis (OA) in combination with Famotidine

Fever

Headache

Menstrual Distress (Dysmenorrhea)

When to interrupt dosage

The prescribed amount of Ibu is contingent upon the established condition. The dosage fluctuates, in accordance with the procedure of delivery indicated in the table beneath.

Condition

Dosage

Administration

Spasm

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Muscle Relaxation

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Analgesics

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Arthritis, Gouty

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Premature Birth

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Chronic Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Migraine

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Migraine Disorders

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Muscle Spasticity

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Dysmenorrhea

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Acute Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Primary Dysmenorrhoea

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Opioids

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Stomach Ulcer

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Nasal Congestion

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Cystic Fibrosis

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Juvenile arthritis

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Pain

200.0 mg, , 50.0 mg/mL, 100.0 mg/mL, 100.0 mg, 800.0 mg, 600.0 mg, 400.0 mg, 4.0 mg/mg, 4.0 mg, 20.0 mg/mL, 220.0 mg, 6.0 mg/mg, 8.0 mg/mg, 300.0 mg, 50.0 mg, 10.0 mg/mL, 256.0 mg, 5.0 mg/mL, 800.0 mg/mL, 1.0 mg/mL, 400.0 mg/mL, 0.02 mg/mg, 97.5 mg, 0.2 mg, 8.0 mg/mL, 0.2 mg/mg, 125.0 mg, 40.0 mg/mL

Oral, Tablet, film coated - Oral, , Tablet, film coated, Tablet, coated, Suspension - Oral, Tablet, coated - Oral, Tablet, sugar coated, Tablet, sugar coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Suspension, Tablet, chewable, Tablet - Oral, Tablet, Kit, Suspension / drops, Suspension / drops - Oral, Liquid - Oral, Liquid, Capsule, Capsule - Oral, Capsule, coated, Tablet, chewable - Oral, Intravenous, Solution - Intravenous, Kit; Tablet - Oral, Kit; Tablet, Capsule; Kit, Capsule; Kit - Oral, Solution, Injection, solution - Intravenous, Injection, solution, Tablet, extended release, Tablet, extended release - Oral, Kit - Oral; Topical, Oral; Topical, Kit - Oral, Solution - Oral, Capsule, coated - Oral, Injection - Intravenous, Injection, Topical, Cream - Topical, Cream, Kit - Topical, Gel - Topical, Gel, Kit - Ophthalmic; Oral; Respiratory (inhalation); Topical, Ophthalmic; Oral; Respiratory (inhalation); Topical, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated, Cream; Kit; Liquid; Ointment; Tablet; Tablet, chewable; Tablet, film coated - Oral; Topical, Solution - Topical, Solution / drops - Oral, Solution / drops

Warnings

Ibu Contraindications

Condition

Risk Level

Notes

Coronary Artery Bypass Grafting

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Ibu.

Common Ibu Drug Interactions

Drug Name

Risk Level

Description

Brigatinib

Major

The metabolism of Brigatinib can be decreased when combined with Ibuprofen.

Cabazitaxel

Major

The metabolism of Cabazitaxel can be decreased when combined with Ibuprofen.

Enasidenib

Major

The metabolism of Enasidenib can be decreased when combined with Ibuprofen.

Erlotinib

Major

The metabolism of Erlotinib can be decreased when combined with Ibuprofen.

Fluorouracil

Major

The metabolism of Fluorouracil can be decreased when combined with Ibuprofen.

image of a doctor in a lab doing drug, clinical research

Ibu Novel Uses: Which Conditions Have a Clinical Trial Featuring Ibu?

Currently, there are no active clinical trials investigating potential novel uses of Ibu to ameliorate any condition.

Condition

Clinical Trials

Trial Phases

Premature Birth

24 Actively Recruiting

Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1

Rheumatoid Arthritis

53 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Influenza

0 Actively Recruiting

Pain

0 Actively Recruiting

Aquaporin 2

3 Actively Recruiting

Phase 3, Not Applicable, Phase 2

Chronic Pain

118 Actively Recruiting

Not Applicable, Phase 2, Phase 4, Phase 3, Early Phase 1, Phase 1

Migraine

48 Actively Recruiting

Phase 4, Not Applicable, Phase 1, Phase 3, Phase 2, Early Phase 1

Muscle Relaxation

0 Actively Recruiting

Juvenile arthritis

6 Actively Recruiting

Phase 2, Not Applicable, Phase 3

Migraine

15 Actively Recruiting

Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4

Acute Pain

2 Actively Recruiting

Not Applicable, Phase 1

Primary Dysmenorrhoea

2 Actively Recruiting

Not Applicable

Nasal Congestion

0 Actively Recruiting

Catarrh

0 Actively Recruiting

Pericarditis

2 Actively Recruiting

Phase 2, Phase 3

Arthritis, Gouty

0 Actively Recruiting

Insomnia

0 Actively Recruiting

Pain

0 Actively Recruiting

Cystic Fibrosis

0 Actively Recruiting

Pain

0 Actively Recruiting

Ibu Reviews: What are patients saying about Ibu?

3.7

Patient Review

2/2/2009

Ibu for Joint Damage causing Pain and Loss of Function

I'm currently taking 2400mg/day and would like to increase my dosage to 3200mg. Is this possible? I haven't experienced any negative side effects so far.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about ibu

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is a normal IBU?

"The bitterness in American mass market lagers ranges from 5 to 10 IBUs, Bavarian hefeweizens from 8 to 12 IBUs, amber lagers from 20 to 25 IBUs, American pale ales from 35 to 40 IBUs, American India pale ales (IPAs) from 55 to 70 IBUs, and “double IPAs” and American barley wines from 65 to 100 IBUs."

Answered by AI

What is considered a high IBU?

"There are beers with IBU ratings of over 1000, but most beer has an IBU rating of between 5 and 120. 5 is very low bitterness and 120 is very high bitterness."

Answered by AI

Is 40 IBU bitter?

"Malt adds sweetness, so maltier beers can come across as sweeter, like a dark stout. Guinness, with more malt, tastes sweeter to most drinkers than Odell 90 Schilling, a Scottish-style ale that has a bitter bite on the finish."

Answered by AI

What does IBU stand for?

".

IBU stands for International Bitterness Units, which is a scale used to measure the level of bitterness in a beer. The more specific measurement of IBUs gauges the parts per million of isohumulone from hops in a beer, which is what gives beer its bitterness."

Answered by AI

Clinical Trials for Ibu

Image of University of Texas Medical Branch in Galveston, United States.

Middle Meningeal Artery Stimulation for Migraine

18 - 100
All Sexes
Galveston, TX

This study is testing a new way to help with migraine headaches. Researchers want to see if it's safe and doable to stimulate a blood vessel in the head (called the middle meningeal artery) with microcatheters and microwires. This has never been done before for migraines and is an investigational treatment that is not part of standard migraine treatment. This stimulation would happen just before giving the standard lidocaine treatment, which is already routinely used for migraines. The goal is to see whether this new step could help improve headache outcomes. Two FDA-cleared medical devices will be used, the Cadwell Cascade 32 PRO and the Cadwell Guardian IONM System, to perform the stimulation and monitoring. In this study, the Cascade 32 PRO will be used in a way that is not part of its usual approved purpose (this is called "off-label" use) to gently deliver electrical pulses through a microcatheter. The Cadwell Guardian IONM System will be used in its normal, FDAapproved way for continuous monitoring during stimulation.

Recruiting
Has No Placebo

University of Texas Medical Branch

Peter Kan, MD,MPH

Image of Cincinnati Urogynecology Associates in Cincinnati, United States.

Nitrous Oxide for Pain During Bladder Botox Injections

18+
Female
Cincinnati, OH

The goal of this clinical trial is to assess if a mix of nitrous oxide and oxygen can improve pain control during bladder Botox injections. The primary question it aims to answer is: Does using nitrous oxide lower the overall level of pain during the procedure? Researchers will compare a 50:50 nitrous oxide/oxygen mixture (administered with the Pro-Nox system) plus standard care (with lidocaine in the bladder) to sham mask plus standard care to see if nitrous oxide works better for lowering pain. Participants will: * Receive their bladder Botox injection in the office setting * Either use nitrous oxide/oxygen plus standard care during the procedure, or sham mask plus standard care * Answer brief questions about pain, anxiety, satisfaction, and willingness to repeat the procedure

Phase 4
Waitlist Available

Cincinnati Urogynecology Associates (+1 Sites)

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Image of University of North Carolina at Chapel Hill in Chapel Hill, United States.

Pain Medicines for Period Pain in Crohn's Disease

18 - 44
Female
Chapel Hill, NC

The purpose of this pilot study is to prepare for a larger study that will compare the effectiveness and safety of two common pain medications, ibuprofen and acetaminophen, to help treat period cramps in women with Crohn's disease. The goal of this study is to identify any challenges in running a larger study. The investigators will track how many people sign up for the study, how well participants follow the study plan, how many people stay in the study, and whether they are able to complete all the study activities, such as taking the medication, submitting samples, and filling out surveys. During the study, participants will undergo a screening visit that includes a blood draw, physical exam, pregnancy test, stool testing, and complete surveys about Crohn's disease and menstrual cycles. Once this visit is complete, the rest of the study will occur at home. Participants will be assigned to take either ibuprofen or acetaminophen to help treat period cramps for four menstrual cycles in a row. Participants will take ibuprofen for two cycles and acetaminophen for two cycles. Participants will know which medication is being taken at any given time, but the order in which they take the medications will be randomly assigned. Before each menstrual cycle, participants will submit a stool sample and fill out a short (\<1 minute) electronic survey. When participants develop period cramps, they will take the assigned medication for three days and fill out short (\<1 minute) electronic surveys about their cramps. After participants finish taking the medication for three days, they will submit another stool sample and fill out two more short (\<1 minute) electronic surveys. After have completing this process for four menstrual cycles, a remote interview with a researcher to give feedback on the study will be conducted.

Waitlist Available
Has No Placebo

University of North Carolina at Chapel Hill

Erica J Brenner, MD, MSCR

Image of AltaSciences, Inc in Cypress, United States.

SBS-147 Safety Study

18 - 55
All Sexes
Cypress, CA

This study is part of the HEAL Initiative supported by the NIH. The purpose of this study is to learn how safe the study drug, SBS-147, is and how people's bodies respond to and process it. Researchers will also look for any side effects that may occur when taking SBS-147. Some participants will receive SBS-147, and others will receive a placebo, which looks the same but does not contain any medicine. This helps researchers fairly compare results. The study includes two parts: Single-Dose Group, where Participants receive SBS-147 or placebo one time. Multiple-Dose Group, where Participants receive SBS-147 or placebo once or twice daily for 7 days.

Phase 1
Waitlist Available

AltaSciences, Inc

Jeff Reich, MD

Sparian Biosciences, Inc

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Image of Royal Alexandra Hospital in Edmonton, Canada.

Oxygen Concentration for Premature Birth

No minimum age - 10
All Sexes
Edmonton, Canada

This study is aims to examine the best amount of oxygen to give preterm babies (born between 32 and 35 weeks) right after birth. In the past, doctors used high levels of oxygen, but research has shown that using lower levels might help reduce the risk of death in full-term babies without harming brain development. However, investigators don't know the best oxygen level for babies born a little early (32 to 35 weeks). Some early data suggests that giving lower oxygen levels (FiO2 0.3) may not help babies reach healthy oxygen levels by 5 minutes after birth. This study will compare two oxygen levels-FiO2 0.6 and FiO2 0.3 to see which helps babies breathe better and need less ongoing breathing support. Researchers will study over 1,500 babies in hospitals across Alberta, Canada, to find the safest approach for these babies.

Waitlist Available
Has No Placebo

Royal Alexandra Hospital

Georg Schmolzer

Image of Arizona State University in Phoenix, United States.

App-based Breathing Program for Migraine

18+
All Sexes
Phoenix, AZ

Migraine is one of the most common neurological disorders, characterized by recurrent headaches, sensitivity to light and movement, nausea, and autonomic dysregulation. Although mind-body interventions like biofeedback have shown their efficacy, they remain underutilized due to barriers such as transportation, time constraints, lack of awareness, stigma, and cost. A targeted approach to enhancing HRV is HRV biofeedback (HRVB), a technique using visual or auditory feedback to help people regulate HRV through slow-paced breathing and positive emotional regulation to promote ANS balance and emotional resilience. Investigators will conduct a remotely delivered pilot RCT of an 8-week, 10 min/day, novel app-based HRVB intervention compared to a sham control intervention (matching intervention time and attention with no biofeedback component) in adult with chronic migraine. Investigators hypothesize data collected from the study will: a) support the feasibility and acceptability of the remotely delivered app-based HRVB intervention among adults with chronic migraine, and b) provide insights into refining the intervention by examining patterns of change in migraine and psychological outcomes from pre- to post-intervention.

Waitlist Available
Online Trial

Arizona State University

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