Floxin Otic

Otitis Externa, Epididymitis, Cervicitis + 17 more

Treatment

1 FDA approval

20 Active Studies for Floxin Otic

Treatment for

Otitis Externa

What is Floxin Otic

OfloxacinThe Generic name of this drug

Treatment SummaryCiprofloxacin is a synthetic antibiotic that stops bacteria from replicating by inhibiting their DNA's ability to form into a coil.

Floxinis the brand name

image of different drug pills on a surface

Floxin Otic Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Floxin

Ofloxacin

1990

149

Approved as Treatment by the FDA

Ofloxacin, also called Floxin, is approved by the FDA for 1 uses which include Urinary Tract Infection (UTI) .

Urinary Tract Infection (UTI)

Effectiveness

How Floxin Otic Affects PatientsOfloxacin is an antibiotic that works by stopping bacteria from making copies of their DNA. It works especially well on the bacteria that cause illness, as the drug binds 100 times more strongly to the bacteria's DNA than to a human's DNA. Ofloxacin is effective against both Gram-positive and Gram-negative bacteria, meaning it can fight a wide range of bacterial infections.

How Floxin Otic works in the bodyOfloxacin works by interfering with the enzymes responsible for allowing DNA to be replicated and transcribed. By blocking these enzymes, the drug stops cells from dividing and multipliying, thus treating the infection.

When to interrupt dosage

The proposed dosage of Floxin Otic is contingent upon the diagnosed affliction, including Urethritis, Cervicitis and Urinary Tract Infection (UTI). The amount of dosage is regulated by the method of delivery (e.g. Oral or Solution) delineated in the table underneath.

Condition

Dosage

Administration

Cystitis

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Prostatitis

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Corneal Ulcer

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Spontaneous Bacterial Peritonitis (SBP)

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Diarrhea

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Otitis Externa

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Epididymitis

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Urinary Tract Infection (UTI)

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Gonorrhea

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Otitis Media

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Hansen's Disease

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Pink Eye

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Acute Coryza

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Bacterial Infections

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Community Acquired Pneumonia (CAP)

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Acute Otitis Media (AOM)

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Cervicitis

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Urethritis

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Urinary tract infection

3.0 mg/mL, , 200.0 mg, 300.0 mg, 400.0 mg, 0.3 %, 600.0 mg, 20.0 mg/mL

Solution / drops - Ophthalmic, , Solution / drops, Ophthalmic, Auricular (otic), Solution / drops - Auricular (otic), Solution, Solution - Auricular (otic), Oral, Tablet, film coated, Tablet, film coated - Oral, Solution - Ophthalmic, Tablet, coated, Tablet, coated - Oral, Tablet, Tablet - Oral, Intravenous, Liquid, Liquid - Intravenous

Warnings

Floxin Otic Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Floxin Otic.

Common Floxin Otic Drug Interactions

Drug Name

Risk Level

Description

Amiodarone

Major

The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Amiodarone.

Amitriptyline

Major

Ofloxacin may increase the QTc-prolonging activities of Amitriptyline.

Anagrelide

Major

The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Anagrelide.

Arsenic trioxide

Major

The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Arsenic trioxide.

Artemether

Major

The risk or severity of QTc prolongation can be increased when Ofloxacin is combined with Artemether.

Floxin Otic Toxicity & Overdose RiskThe lowest toxic dose of this drug in mice has been found to be 5450 mg/kg when taken orally.

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Floxin Otic Novel Uses: Which Conditions Have a Clinical Trial Featuring Floxin Otic?

46 active clinical trials are currently in progress to assess the effectiveness of Floxin Otic in providing relief from Corneal Ulcer, Acute Coryza and Otitis Media.

Condition

Clinical Trials

Trial Phases

Epididymitis

0 Actively Recruiting

Pink Eye

5 Actively Recruiting

Phase 4, Phase 3, Not Applicable, Phase 2

Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)

0 Actively Recruiting

Prostatitis

3 Actively Recruiting

Not Applicable, Phase 4

Acute Otitis Media (AOM)

3 Actively Recruiting

Not Applicable

Urinary Tract Infection (UTI)

24 Actively Recruiting

Phase 2, Phase 1, Phase 4, Phase 3, Not Applicable

Spontaneous Bacterial Peritonitis (SBP)

0 Actively Recruiting

Otitis Media

0 Actively Recruiting

Otitis Externa

0 Actively Recruiting

Corneal Ulcer

0 Actively Recruiting

Gonorrhea

0 Actively Recruiting

Urethritis

0 Actively Recruiting

Hansen's Disease

0 Actively Recruiting

Bacterial Infections

1 Actively Recruiting

Phase 4

Acute Coryza

0 Actively Recruiting

Cervicitis

1 Actively Recruiting

Not Applicable

Cystitis

0 Actively Recruiting

Community Acquired Pneumonia (CAP)

1 Actively Recruiting

Not Applicable

Urinary tract infection

2 Actively Recruiting

Phase 2, Phase 3

Diarrhea

0 Actively Recruiting

Floxin Otic Reviews: What are patients saying about Floxin Otic?

5Patient Review

10/3/2007

Floxin Otic for Acute Outer Ear Pseudomonas Aeruginosa Bacterial Infection

This treatment stopped my discharge, relieved my pain, and got rid of infection.

4Patient Review

10/2/2007

Floxin Otic for Chronic Inflammation of Middle Ear with Discharge of Pus

Floxin, when used in tandem with an oral antibiotic, really helped to ease my middle ear infection symptoms and much faster than the oral antibiotics alone. I also appreciate that it comes in single dose packets because I can't always tell how many drops I've put in my ear after a few.

4Patient Review

2/23/2014

Floxin Otic for Outer Ear Inflammation caused by Allergy or Infection

Amoxocillin didn't do the trick for my ear infection, but this Floxin treatment did.

1Patient Review

4/8/2011

Floxin Otic for Chronic Inflammation of Middle Ear with Discharge of Pus

My daughter's doctor prescribed this, but it costs more than one hundred dollars to fill the prescription. I'm not sure if it's worth it or if the infection will go away on its own with oral antibiotics.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about floxin otic

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is Floxin Otic used for?

"Ofloxacin belongs to the family of antibiotics. It is used to treat infections of the ear and middle ear."

Answered by AI

What are Floxin ear drops?

"It will not work for other types of ear infections.

Ofloxacin is used to treat swimmer's ear or ear canal infections, as well as middle ear infections. It does so by halting the growth of bacteria. Ofloxacin is classified as a quinolone antibiotic. This medication can only treat bacterial ear infections and won't be effective for other types of ear infections."

Answered by AI

How fast does ofloxacin otic work?

"If you are taking ofloxacin otic to treat an infection, you should begin to feel better during the first few days of treatment. If your symptoms do not improve after one week or if they get worse, you should call your doctor. You should continue using ofloxacin otic until you finish the prescription, even if you begin to feel better."

Answered by AI

How long do you leave ofloxacin in ear?

"Tilt your head so that the affected ear is pointing upward. This will allow the eardrops to flow more easily into the ear canal. After five minutes, turn your head to the opposite side so that the other ear is pointing upward, and repeat the application process. If you are treating both ears, repeat this process for the other ear."

Answered by AI

Clinical Trials for Floxin Otic

Image of Andover Eye Associates in Andover, United States.

TL-925 for Allergic Eye

This trial will involve 70 participants who will be randomly assigned to receive either TL-925 eye drops or a placebo. The study will assess the effectiveness of TL-925 in treating allergic conjunctiv

Andover Eye AssociatesTelios Pharma, Inc.

Image of Cleveland Clinic Foundation in Cleveland, United States.

Oral care treatment as usual for Oral Bacterial Infection

This trial is going to compare the effectiveness of two different oral care treatments in patients who have a tube in their throat. The goal of the trial is to see which treatment can reduce the amount of bacteria

Waitlist Available

Cleveland Clinic FoundationMarcelo Gama de Abreu, MD

Image of Duke University in Durham, United States.

Cefiderocol for Bacterial Infections in Newborns and Infants

This trial studies the effectiveness of cefiderocol in treating bacterial infections in newborns & babies under 3 months.

Duke University (+1 Sites)Medical DirectorShionogi

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Electronic Data Intervention for Respiratory and Ear Infections

Philadelphia, PA

This trial aims to use electronic data to improve antibiotic use in patients with pneumonia, pharyngitis, and ear infections, and the care provided by clinicians.

Children's Hospital of Philadelphia (+1 Sites)Ebbing Lautenbach, MD, MSCE

Have you considered Floxin Otic clinical trials? We made a collection of clinical trials featuring Floxin Otic, we think they might fit your search criteria.

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Shockwave Therapy for Erectile Dysfunction

This trial studies the effectiveness of two treatments for erectile dysfunction and pelvic pain: focused shockwave therapy and radial shockwave therapy.

Cleveland Clinic FoundationPetar Bajic, MD

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Tavilermide Eye Drops for Dry Eye

This trial will test if a new eye drop can treat dry eye symptoms better than a fake drop.

Waitlist Available

Eye Doctors of Arizona (+28 Sites)Mimetogen Pharmaceuticals USA, Inc.

Image of University of Missouri in Columbia, United States.

Antibiotics for Cat Bite Injuries

This trial investigates duration of prophylactic antibiotics & placebo control for cat bites to the hand/forearm to reduce incidence of infection.

University of MissouriKevin M Klifto, DO, PharmD

Image of Brigham and Women's Hospital in Boston, United States.

Remote Intensive Outpatient Program for Opioid Use Disorder

This trial will study if an online program can help decrease opioid use for hospitalized people with injection-related infections.

Brigham and Women's Hospital

Have you considered Floxin Otic clinical trials? We made a collection of clinical trials featuring Floxin Otic, we think they might fit your search criteria.

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ATM-AVI for Bacterial Infections

This trial is studying the safety/effectiveness of ATM/AVI as a treatment for children with serious infections. They will be given an intravenous dose based on weight/kidney function, and may be switched to oral therapy.

Le Bonheur Children's Hospital (+5 Sites)Pfizer CT.gov Call CenterPfizer

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Phage Therapy for MDRO Decolonization

Philadelphia, PA

This trial will test if a new treatment using bacteria from poop can help get rid of bacteria that don't respond to antibiotics.

Waitlist Available

Hospital of the University of PennsylvaniaBrendan J Kelly

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Anti-inflammatory Drugs for Elevated Prostate-Specific Antigen Levels

This trial will test whether anti-inflammatory drugs can lower PSA levels in men w/ elevated PSA, reducing unnecessary prostate biopsies.

Albany Medical CenterBadar Mian, MD

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Mouthrinses for Oral Microbiome Health

This trial studies the effects of two mouthwashes on bacteria and 3 viruses in the mouth and gut. Participants will make 5 visits over 180 days, spending 2.5 hours in total. Fecal matter will be collected in some.

Senior-friendly

Beckman Laser Institute (+1 Sites)Dr. Petra Wilder-Smith

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