← Back to Search

Tetracycline Antibiotic

Doxycycline Hyclate 20 MG for Golfer's Elbow

Phase 1
Waitlist Available
Led By Brett G Toresdahl, MD
Research Sponsored by Hospital for Special Surgery, New York
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Atraumatic unilateral elbow pain of ≥ 6 weeks duration
Pain with gripping and/or resisted wrist extension with the elbow extended
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Study Summary

This trial is testing if a lower dose of doxycycline can help treat elbow tendinopathy and if patients will be willing to follow the prescription.

Who is the study for?
This trial is for men and women over 18 with elbow tendinopathy, which includes golfer's or tennis elbow that's been painful for at least 6 weeks. Participants need internet access and haven't had surgery on the affected elbow. Pregnant individuals, those not using contraception, non-English speakers, or people with certain medical conditions are excluded.Check my eligibility
What is being tested?
The study tests if a low-dose antibiotic called Doxycycline can help improve elbow tendinopathy by inhibiting enzymes that break down tissue. It also checks if patients will follow the medication and exercise regimen prescribed.See study design
What are the potential side effects?
Doxycycline may cause side effects like digestive issues (esophagitis or ulcers), reactions in those allergic to tetracyclines, and potential drug interactions. Specific side effects related to tendon health aren't mentioned but could be monitored.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have had elbow pain for 6 weeks or more without injury.
Select...
I experience pain when I grip something or extend my wrist with my arm straight.
Select...
I experience pain when my wrist and fingers are bent back with my arm straight.
Select...
I have elbow pain on the inner or outer side.
Select...
I am 18 years old or older.
Select...
I experience elbow pain when I move or use my arm.
Select...
I have been diagnosed with tennis elbow or golfer's elbow.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Primarily a feasibility study of SD-doxycycline as an adjunctive treatment for elbow tendinopathy (Compliance)
Receptiveness
Secondary outcome measures
Clinical outcomes - Grip strength
Clinical outcomes - MMP
Clinical outcomes - PRTEE
+2 more

Trial Design

1Treatment groups
Experimental Treatment
Group I: SD-doxycycline groupExperimental Treatment1 Intervention
12 weeks SD-doxycycline: doxycycline hyclate 20 mg tablet by mouth twice daily

Find a Location

Who is running the clinical trial?

Hospital for Special Surgery, New YorkLead Sponsor
242 Previous Clinical Trials
61,877 Total Patients Enrolled
Brett G Toresdahl, MDPrincipal InvestigatorHospital for Special Surgery, New York

Media Library

Doxycycline Hyclate 20 MG (Tetracycline Antibiotic) Clinical Trial Eligibility Overview. Trial Name: NCT04686799 — Phase 1
Golfer's Elbow Research Study Groups: SD-doxycycline group
Golfer's Elbow Clinical Trial 2023: Doxycycline Hyclate 20 MG Highlights & Side Effects. Trial Name: NCT04686799 — Phase 1
Doxycycline Hyclate 20 MG (Tetracycline Antibiotic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04686799 — Phase 1

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What have studies revealed about the safety of Doxycycline Hyclate 20 MG?

"Our team at Power has assigned Doxycycline Hyclate 20 MG a score of 1 due to the limited data supporting its efficacy and safety. This is a Phase 1 trial, after all."

Answered by AI

Does this research endeavor still accept new volunteers?

"Affirmative. An examination of clinicaltrials.gov reveals that this investigation is actively recruiting patients, having been initially announced on December 3rd 2020 and last updated March 29th 2022. 25 participants are needed from a solitary location for the trial to be successful."

Answered by AI

How many participants are included in this clinical experiment?

"Affirmative. According to the clinicaltrials.gov website, this medical research has been open for recruitment since December 3rd 2020 and was most recently updated on March 29th 2022. 25 individuals are sought from a single location."

Answered by AI

To whom is enrolment in this trial accessible?

"The recruitment criteria for this clinical trial necessitates that participants have lateral epicondylitis and are between 18-60 years in age. At the moment, there is a quota of 25 patients to be enrolled into the study."

Answered by AI

What conditions can be remedied by regular consumption of Doxycycline Hyclate 20 MG?

"Intractable acne, disease processes, and trachomatous inflammation can all be managed with the prescription drug Doxycycline Hyclate 20 MG."

Answered by AI

What objectives is this clinical trial hoping to accomplish?

"This 12-week trial has two primary objectives: determining the efficacy of SD-doxycycline as an adjunctive treatment for lateral elbow tendinopathy and collecting preliminary data to power a randomized controlled trial in the future. Secondary goals focus on measuring ultrasound tendinopathy grade, matrix metalloproteinase inhibition activity and collagen production/connective tissue anabolism via blood test, and patient rated tennis elbow evaluation scores at various time points throughout the study."

Answered by AI

Is there a cutoff age for participants of this medical investigation?

"This study seeks participants that are above the age of majority and below 60 years old."

Answered by AI

Who else is applying?

What state do they live in?
New Jersey
What portion of applicants met pre-screening criteria?
Did not meet criteria
~4 spots leftby Nov 2024