What is Flarex
FluorometholoneThe Generic name of this drug
Treatment SummaryPrednisolone is a steroid eye drop that is used to reduce inflammation and allergies in the eyes. It can also be used to treat skin conditions such as eczema and psoriasis.
FMLis the brand name
Flarex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
FML
Fluorometholone
1972
11
Approved as Treatment by the FDA
Fluorometholone, also called FML, is approved by the FDA for 1 uses such as Ocular Inflammation .Ocular Inflammation
Effectiveness
How Flarex Affects PatientsCorticosteroids, such as fluorometholone, help reduce inflammation caused by a variety of agents, but can also slow down the healing process. They work by decreasing swelling, stopping the formation of blood clots, preventing white blood cells from gathering at the site of inflammation, blocking the growth of new blood vessels, stopping the growth of cells that produce collagen and scar tissue, and reducing the formation of scars.
How Flarex works in the bodyOcular corticosteroids are believed to reduce inflammation by blocking the formation of certain molecules that cause inflammation. This is done by creating proteins called lipocortins that stop the release of the building block of these molecules, called arachidonic acid. Corticosteroid drugs then bind to a receptor inside a cell nucleus, causing the expression of certain genes that control inflammation.
When to interrupt dosage
The prescribed dosage of Flarex is contingent upon the diagnosed affliction, including Anterior chamber inflammation, eye surgery and Ocular Inflammation. The magnitude of dosage hinges upon the methodology of delivery (e.g. Ointment - Ophthalmic or Suspension - Ophthalmic) featured in the table below.Condition
Dosage
Administration
Anterior chamber inflammation
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
eye surgery
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Ocular Inflammation
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Swelling
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Vascular injection
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Inflammation Corneal
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Inflammation
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Allergic Conjunctivitis (AC)
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
ocular bacterial infections
, 1.0 mg/mL, 2.5 mg/mL, 0.001 mg/mg, 0.1 %, 0.25 %, 0.001 mL/mL
Ointment - Ophthalmic, Suspension - Ophthalmic, , Ophthalmic, Suspension / drops, Suspension, Solution / drops - Ophthalmic, Suspension / drops - Ophthalmic, Ointment, Solution / drops
Warnings
Flarex has five contraindications and ought not be combined with any of the circumstances noted in the following table.Flarex ContraindicationsCondition
Risk Level
Notes
Eye Infections, Fungal
Do Not Combine
conjunctiva
Do Not Combine
Eye
Do Not Combine
conjunctiva
Do Not Combine
viral disease of cornea and conjunctiva caused by Varicella Zoster
Do Not Combine
Common Flarex Drug Interactions
Drug Name
Risk Level
Description
2-Methoxyethanol
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with 2-Methoxyethanol.
9-(N-methyl-L-isoleucine)-cyclosporin A
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.
Abatacept
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with Abatacept.
Abetimus
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with Abetimus.
Acteoside
Major
The risk or severity of adverse effects can be increased when Fluorometholone is combined with Acteoside.
Flarex Toxicity & Overdose RiskSide effects of corticosteroids can include inflammation of the front of the eye, inflammation of the cornea, redness of the eyes, and drooping of the eyelid. In high doses, corticosteroids can be fatal to rats, with a lethal dose of 234mg/kg.
Flarex Novel Uses: Which Conditions Have a Clinical Trial Featuring Flarex?
189 active clinical trials are presently exploring the potential benefits of Flarex in mitigating Inflammation, Swelling and Ocular Inflammation.Condition
Clinical Trials
Trial Phases
Inflammation
171 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Swelling
0 Actively Recruiting
Ocular Inflammation
2 Actively Recruiting
Phase 2, Phase 4
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 1
eye surgery
0 Actively Recruiting
Vascular injection
0 Actively Recruiting
ocular bacterial infections
0 Actively Recruiting
Inflammation Corneal
0 Actively Recruiting
Anterior chamber inflammation
0 Actively Recruiting
Flarex Reviews: What are patients saying about Flarex?
5Patient Review
2/12/2010 This drug is amazing, my eyes felt better within a day!
5Patient Review
10/18/20093.3Patient Review
6/3/2014 I was using this as directed by my doctor, but then Alcon discontinued the product. I'm very disappointed.
Patient Q&A Section about flarex
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long should you use Flarex?
"If your symptoms do not improve after 2 days of treatment, call your doctor. If you use this medicine for longer than 10 days, you may needfrequent vision tests to check the pressure inside your eyes."
Answered by AI
How often can I use Flarex?
"For eye conditions caused by swelling, adults should use one drop in the affected eye two to four times a day. For the first 24 to 48 hours, the medicine can be used every 4 hours, as directed by a doctor."
Answered by AI
What are Flarex drops used for?
"This medication is meant to treat conditions that cause inflammation in the eye, such as the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye."
Answered by AI