Ergamisol

Hookworm Infections, Ascaris lumbricoides infection, Hookworm Infections + 5 more

Treatment

0 Active Studies for Ergamisol

Treatment for

Hookworm Infections

What is Ergamisol

LevamisoleThe Generic name of this drug

Treatment SummaryLevamisole is a medication used to treat parasitic, viral, and bacterial infections. It was first used in 1969 and approved by the FDA in 1990 as a treatment for colon cancer. Levamisole was also used as an antirheumatic drug in the 70s and 80s for rheumatoid arthritis. This drug has been studied for its potential to treat other immune-mediated diseases, but it was withdrawn from the American market in 2000 due to serious side effects, such as agranulocytosis. Levamisole is sometimes used as an adulterant in cocaine and can lead to dangerous effects in

Ergamisol Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Levamisole

Effectiveness

How Ergamisol Affects PatientsLevamisole is a drug used to treat worm infections in humans and animals. It works by targeting a receptor in the worms and can also help boost the immune system in certain cases. Specifically, it has been shown to increase the number of natural killer cells (NK cells) and activated T-cells in people with Stage III colon cancer who took it as an adjuvant alongside 5FU.

How Ergamisol works in the bodyLevamisole is used to fight parasites and cancer. It works on parasites by blocking their ability to reproduce, and on cancer cells by restoring the immune system. It helps the immune system by stimulating the production of antibodies, activating and multiplying T-cells, enhancing monocyte and macrophage functions, and increasing neutrophil mobility.

When to interrupt dosage

The suggested dosage of Ergamisol is contingent upon the recognized circumstance, such as Strongyloides Stercoralis Infection, Necatoriasis due to necator americanus and Enterobius vermicularis infection. The measure of dosage can be found in the table beneath, as per the method of administration (e.g. Tablet - Oral or Tablet).

Condition

Dosage

Administration

Hookworm Infections

50.0 mg,

, Oral, Tablet, Tablet - Oral

Trichuriasis

50.0 mg,

, Oral, Tablet, Tablet - Oral

Ascaris lumbricoides infection

50.0 mg,

, Oral, Tablet, Tablet - Oral

Hookworm Infections

50.0 mg,

, Oral, Tablet, Tablet - Oral

Enterobius vermicularis infection

50.0 mg,

, Oral, Tablet, Tablet - Oral

Colorectal Neoplasms

50.0 mg,

, Oral, Tablet, Tablet - Oral

Strongyloides Stercoralis Infection

50.0 mg,

, Oral, Tablet, Tablet - Oral

Adenocarcinoma

50.0 mg,

, Oral, Tablet, Tablet - Oral

Warnings

Ergamisol has four contraindications, which calls for refraining from combining it with any of the conditions listed in the following table.Ergamisol Contraindications

Condition

Risk Level

Notes

Disease

Do Not Combine

Kidney Diseases

Do Not Combine

Disease

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Levamisole may interact with Pulse Frequency

There are 2 known major drug interactions with Ergamisol.

Common Ergamisol Drug Interactions

Drug Name

Risk Level

Description

Albendazole

Moderate

The bioavailability of Albendazole can be increased when combined with Levamisole.

Ivermectin

Moderate

The bioavailability of Ivermectin can be increased when combined with Levamisole.

Ergamisol Toxicity & Overdose RiskThe lowest toxic dose of this drug in pigs has been found to be 40mg/kg when injected, and 180mg/kg when taken orally by rats.

Ergamisol Novel Uses: Which Conditions Have a Clinical Trial Featuring Ergamisol?

There are currently 278 active clinical trials assessing the potential of Ergamisol for treating Necatoriasis due to Necator americanus, Enterobius vermicularis infection and Trichuris Infection.

Condition

Clinical Trials

Trial Phases

Ascaris lumbricoides infection

0 Actively Recruiting

Hookworm Infections

0 Actively Recruiting

Enterobius vermicularis infection

0 Actively Recruiting

Strongyloides Stercoralis Infection

0 Actively Recruiting

Hookworm Infections

0 Actively Recruiting

Colorectal Neoplasms

0 Actively Recruiting

Trichuriasis

0 Actively Recruiting

Adenocarcinoma

0 Actively Recruiting

Patient Q&A Section about ergamisol

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What kind of drug is levamisole?

"Levamisole is a drug used to treat worm infestations. It is approved for use in veterinary medicine in the United States."

Answered by AI

What are the side effects of levamisole?

"Diarrhea, a metallic taste, nausea, anxiety or nervousness, dizziness, a headache, mental depression, and nightmares are all possible side effects of taking this medication."

Answered by AI

Is levamisole safe for humans?

"Levamisole can be highly toxic to humans, but most cocaine users wouldn't care even if they knew the drug was contaminated with it. Physicians who treat cocaine users need to be aware of this."

Answered by AI

Why was levamisole taken off the market?

"Levamisole was taken off the market in America in 2000 because it can cause potentially fatal side effects, like blood cell loss. Curiously, levamisole has been found mixed in with cocaine, and can result in a whole host of problems for people using cocaine that have been exposed to it."

Answered by AI