Ergamisol
Hookworm Infections, Ascaris lumbricoides infection, Hookworm Infections + 5 more
Treatment
0 Active Studies for Ergamisol
Treatment for
Hookworm Infections
What is Ergamisol
Levamisole
The Generic name of this drug
Treatment Summary
Levamisole is a medication used to treat parasitic, viral, and bacterial infections. It was first used in 1969 and approved by the FDA in 1990 as a treatment for colon cancer. Levamisole was also used as an antirheumatic drug in the 70s and 80s for rheumatoid arthritis. This drug has been studied for its potential to treat other immune-mediated diseases, but it was withdrawn from the American market in 2000 due to serious side effects, such as agranulocytosis. Levamisole is sometimes used as an adulterant in cocaine and can lead to dangerous effects in
Ergamisol Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Levamisole
0
Effectiveness
How Ergamisol Affects Patients
Levamisole is a drug used to treat worm infections in humans and animals. It works by targeting a receptor in the worms and can also help boost the immune system in certain cases. Specifically, it has been shown to increase the number of natural killer cells (NK cells) and activated T-cells in people with Stage III colon cancer who took it as an adjuvant alongside 5FU.
How Ergamisol works in the body
Levamisole is used to fight parasites and cancer. It works on parasites by blocking their ability to reproduce, and on cancer cells by restoring the immune system. It helps the immune system by stimulating the production of antibodies, activating and multiplying T-cells, enhancing monocyte and macrophage functions, and increasing neutrophil mobility.
When to interrupt dosage
The suggested dosage of Ergamisol is contingent upon the recognized circumstance, such as Strongyloides Stercoralis Infection, Necatoriasis due to necator americanus and Enterobius vermicularis infection. The measure of dosage can be found in the table beneath, as per the method of administration (e.g. Tablet - Oral or Tablet).
Condition
Dosage
Administration
Hookworm Infections
50.0 mg,
Oral, Tablet - Oral, , Tablet
Trichuriasis
50.0 mg,
Oral, Tablet - Oral, , Tablet
Hookworm Infections
50.0 mg,
Oral, Tablet - Oral, , Tablet
Strongyloides Stercoralis Infection
50.0 mg,
Oral, Tablet - Oral, , Tablet
Adenocarcinoma
50.0 mg,
Oral, Tablet - Oral, , Tablet
Enterobiasis
50.0 mg,
Oral, Tablet - Oral, , Tablet
Ascaris lumbricoides infection
50.0 mg,
Oral, Tablet - Oral, , Tablet
Colorectal Neoplasms
50.0 mg,
Oral, Tablet - Oral, , Tablet
Warnings
Ergamisol has four contraindications, which calls for refraining from combining it with any of the conditions listed in the following table.
Ergamisol Contraindications
Condition
Risk Level
Notes
Disease
Do Not Combine
Kidney Diseases
Do Not Combine
Disease
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Levamisole may interact with Pulse Frequency
There are 2 known major drug interactions with Ergamisol.
Common Ergamisol Drug Interactions
Drug Name
Risk Level
Description
Albendazole
Moderate
The bioavailability of Albendazole can be increased when combined with Levamisole.
Ivermectin
Moderate
The bioavailability of Ivermectin can be increased when combined with Levamisole.
Ergamisol Toxicity & Overdose Risk
The lowest toxic dose of this drug in pigs has been found to be 40mg/kg when injected, and 180mg/kg when taken orally by rats.
Ergamisol Novel Uses: Which Conditions Have a Clinical Trial Featuring Ergamisol?
There are currently 278 active clinical trials assessing the potential of Ergamisol for treating Necatoriasis due to Necator americanus, Enterobius vermicularis infection and Trichuris Infection.
Condition
Clinical Trials
Trial Phases
Ascaris lumbricoides infection
0 Actively Recruiting
Hookworm Infections
0 Actively Recruiting
Enterobiasis
0 Actively Recruiting
Strongyloides Stercoralis Infection
0 Actively Recruiting
Hookworm Infections
0 Actively Recruiting
Colorectal Neoplasms
0 Actively Recruiting
Trichuriasis
0 Actively Recruiting
Adenocarcinoma
0 Actively Recruiting
Patient Q&A Section about ergamisol
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
What kind of drug is levamisole?
"Levamisole is a drug used to treat worm infestations. It is approved for use in veterinary medicine in the United States."
Answered by AI
What are the side effects of levamisole?
"Diarrhea, a metallic taste, nausea, anxiety or nervousness, dizziness, a headache, mental depression, and nightmares are all possible side effects of taking this medication."
Answered by AI
Is levamisole safe for humans?
"Levamisole can be highly toxic to humans, but most cocaine users wouldn't care even if they knew the drug was contaminated with it. Physicians who treat cocaine users need to be aware of this."
Answered by AI
Why was levamisole taken off the market?
"Levamisole was taken off the market in America in 2000 because it can cause potentially fatal side effects, like blood cell loss. Curiously, levamisole has been found mixed in with cocaine, and can result in a whole host of problems for people using cocaine that have been exposed to it."
Answered by AI