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What is Daypro
OxaprozinThe Generic name of this drug
Treatment SummaryOxaprozin is a type of medication used to reduce pain, inflammation, and stiffness in people with rheumatoid arthritis and osteoarthritis. It is classified as a non-steroidal anti-inflammatory drug (NSAID) and does not contain narcotic components.
Dayprois the brand name
Daypro Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Daypro
Oxaprozin
1992
44
Approved as Treatment by the FDA
Oxaprozin, also known as Daypro, is approved by the FDA for 3 uses such as Osteoarthritis (OA) and Rheumatoid Arthritis, Juvenile .Osteoarthritis (OA)
Rheumatoid Arthritis, Juvenile
Rheumatoid Arthritis
Effectiveness
How Daypro Affects PatientsOxaprozin is a pain reliever and fever reducer that works by blocking the body's production of certain natural substances that cause inflammation. It is used to treat rheumatoid arthritis, osteoarthritis, and menstrual cramps, as well as to reduce mild pain.
How Daypro works in the bodyOxaprozin works to reduce inflammation by blocking the production of prostaglandins. It also helps to reduce fever by increasing blood flow and allowing heat to dissipate from the body. This non-selective NSAID is more effective against COX-1 than COX-2.
When to interrupt dosage
The advised dose of Daypro is contingent upon the determined condition, for example Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile and Osteoarthritis (OA). The exact amount of dosage is contingent upon the technique of administration (e.g. Oral or Tablet, film coated) as detailed in the following table.Condition
Dosage
Administration
Rheumatoid Arthritis
, 600.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Rheumatoid Arthritis, Juvenile
, 600.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Osteoarthritis (OA)
, 600.0 mg
, Oral, Tablet, Tablet - Oral, Tablet, film coated, Tablet, film coated - Oral
Warnings
Daypro has two contraindications, and so should not be ingested when encountering any of the situations outlined in the table below.Daypro ContraindicationsCondition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Pulse Frequency
Do Not Combine
Common Daypro Drug Interactions
Drug Name
Risk Level
Description
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Oxaprozin.
Methotrexate
Major
The serum concentration of Methotrexate can be increased when it is combined with Oxaprozin.
Mifamurtide
Major
The therapeutic efficacy of Mifamurtide can be decreased when used in combination with Oxaprozin.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Oxaprozin is combined with Neomycin.
Omacetaxine mepesuccinate
Major
The risk or severity of bleeding can be increased when Oxaprozin is combined with Omacetaxine mepesuccinate.
Daypro Toxicity & Overdose RiskThe lowest toxic dose of the drug in mice has been found to be 1210mg/kg, in rabbits 172mg/kg, and in rats 4470mg/kg.
Daypro Novel Uses: Which Conditions Have a Clinical Trial Featuring Daypro?
There are 77 active trials assessing the capacity of Daypro to provide relief for Rheumatoid Arthritis, Juvenile Arthritis, Osteoarthritis (OA) and Rheumatoid Arthritis.Condition
Clinical Trials
Trial Phases
Osteoarthritis (OA)
0 Actively Recruiting
Rheumatoid Arthritis, Juvenile
4 Actively Recruiting
Not Applicable, Phase 3
Rheumatoid Arthritis
62 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Daypro Reviews: What are patients saying about Daypro?
5Patient Review
11/22/2011 Daypro has been essential in managing my osteoarthritis. It's been nearly four years since I've started taking it with no negative side effects. The only thing I sometimes experience is a little motion sickness, but that's not really a big deal. Not taking Daypro would mean being in constant pain and barely able to walk, so I'm very grateful for this medication.
5Patient Review
5/7/2012 I have tried going off of this medication before and the severe pain I experience as a result is enough to keep me on it. It's been 5 years now and I don't see that changing anytime soon.
5Patient Review
5/20/20114.7Patient Review
3/10/2014 I've been using this treatment for over a decade and a half. Each time I try to switch to something else, my pain gets worse. This medication doesn't completely eliminate the pain, but it does help dull it.
4.3Patient Review
1/19/2012 I found this treatment to be really helpful after about a week of using it.
4Patient Review
7/13/2013 I was struggling to sleep through the night due to pain in my knee and hip. However, after taking Daypro I was able to rest comfortably for the entire night.
4Patient Review
6/13/2011 This helps take the edge off of my joint pain.
3.7Patient Review
3/24/2014 I experienced mental clouding and unusual tiredness.
3.7Patient Review
4/25/20113Patient Review
2/4/2013 I've been on DayPro for a month to help with my arthritis pain. It's effective, but I've started having strange dreams that are sometimes disturbing. I'm not sure whether the benefits outweigh the drawbacks at this point.
1.7Patient Review
10/16/2012 I had been taking Mobic for over 10 years for arthritis and the effectiveness of it seemed to be diminishing. My dr. suggested daypro. I am only on my 2nd day and realize it needs time to get into my system but can barely move. Does anyone know how long this will take to make a difference? I may have to go back to Mobic if this pain and stiffness doesn't get better.
1Patient Review
6/15/2022 I took Daypro for only 3 weeks after a car accident and I became extremely ill with nausea,a rash with intense itching from head to toes and swollen lymph nodes. A liver biopsy determined that I had drug induced liver cirrhosis from the Daypro. My liver enzymes have remained above normal range since 1996 when this occurred
Patient Q&A Section about daypro
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is daypro the same as ibuprofen?
"The drug oxaprozin, which is also known as Daypro, is an NSAID. This means that it is similar to other medications such as naproxen and ibuprofen. One of the main advantages of this drug is that there is no potential for addiction or abuse, which is a common problem with narcotics."
Answered by AI
How long does daypro take to work?
"This medicine is usually taken regularly in order to help with severe or continuing arthritis. It usually starts working within a week, but in more severe cases it may take up to two weeks or even longer to start feeling better."
Answered by AI
What drug class is daypro?
"Daypro is a member of the NSAIDs drug class."
Answered by AI