Pred Forte

Inflammation, Conjunctivitis, Conjunctivitis + 4 more
Treatment
4 FDA approvals
20 Active Studies for Pred Forte

What is Pred Forte

Prednisolone acetateThe Generic name of this drug
Treatment SummaryPrednisolone acetate is a medication used to treat inflammation and other related conditions. It contains prednisolone, a steroid, combined with an acetate group. Prednisolone acetate was approved by the FDA in 1955.
Blephamideis the brand name
image of different drug pills on a surface
Pred Forte Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Blephamide
Prednisolone acetate
1961
39

Approved as Treatment by the FDA

Prednisolone acetate, also known as Blephamide, is approved by the FDA for 4 uses including Inflammation and Organ Transplantation .
Inflammation
Organ Transplantation
Inflammation
Inflammatory Conditions
Helps manage Inflammatory Conditions

Effectiveness

How Pred Forte Affects PatientsPrednisolone acetate is a type of corticosteroid drug that blocks the body's pro-inflammatory signals and encourages anti-inflammatory signals. Its effects wear off quickly, with a half life of 2-3 hours. Corticosteroids can be taken in doses much higher than the body's natural production, and this has a wide therapeutic window. Taking corticosteroids can have side effects such as suppression of the hypothalamic-pituitary-adrenal axis and increased risk of infections, so patients should be aware of these risks.
How Pred Forte works in the bodyCorticosteroids reduce swelling and stop white blood cells from flowing to sites of inflammation. This is done by changing the expression of certain genes. Corticosteroids also prevent cells from dying and stop the formation of chemicals that cause inflammation. Lower doses of corticosteroids help with inflammation, while higher doses weaken your immune system. Very high doses of corticosteroids can cause too much sodium and too little potassium in the body.

When to interrupt dosage

The advised measure of Pred Forte is contingent upon the identified disorder, including Ocular Infections, Irritations and Inflammations, Ocular Inflammation and Inflammatory Conditions. The sum of dosage differs, according to the technique of delivery (e.g. Ophthalmic or Solution / drops - Ophthalmic) featured in the table below.
Condition
Dosage
Administration
Conjunctivitis
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit
Conjunctivitis
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit
Ocular Infections, Irritations and Inflammations
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit
Organ Transplantation
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit
Eye Infections, Bacterial
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit
Inflammation
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit
Inflammatory Conditions
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ointment, Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Ointment - Ophthalmic, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Solution, Ophthalmic; Topical, Kit - Ophthalmic, Kit

Warnings

Pred Forte has one contraindication and should not be ingested if you are suffering from any of the conditions detailed in the following table.Pred Forte Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Prednisolone Acetate may interact with Pulse Frequency
There are 20 known major drug interactions with Pred Forte.
Common Pred Forte Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Prednisolone acetate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Prednisolone acetate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Prednisolone acetate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Prednisolone acetate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Prednisolone acetate.
Pred Forte Toxicity & Overdose RiskThe lowest toxic dose of prednisolone acetate in mice is 1680mg/kg. People who overdose on this drug may experience more severe side effects of corticosteroids. If the overdose occurred recently, treatment may include stomach pumping or inducing vomiting. For long-term overdose, doctors may reduce the dose or have patients take the drug every other day. An overdose through the eyes is not likely to cause problems.
image of a doctor in a lab doing drug, clinical research

Pred Forte Novel Uses: Which Conditions Have a Clinical Trial Featuring Pred Forte?

At present, 189 active trials are exploring the potential of Pred Forte in alleviating Inflammation, Inflammatory Conditions and Superficial Ocular Infections.
Condition
Clinical Trials
Trial Phases
Inflammation
57 Actively Recruiting
Not Applicable, Early Phase 1, Phase 1, Phase 2, Phase 3, Phase 4
Conjunctivitis
0 Actively Recruiting
Eye Infections, Bacterial
0 Actively Recruiting
Ocular Infections, Irritations and Inflammations
0 Actively Recruiting
Conjunctivitis
0 Actively Recruiting
Organ Transplantation
0 Actively Recruiting
Inflammatory Conditions
1 Actively Recruiting
Phase 2

Pred Forte Reviews: What are patients saying about Pred Forte?

5Patient Review
7/22/2012
Pred Forte for Inflammation of the Eye
I've been on this medication for a few weeks now, three times a day. I'm sure it's effective, but the taste is absolutely vile. It lingers in your mouth for hours afterwards and makes my stomach hurt. I'll be calling the doctor on Monday morning to discuss other options.
5Patient Review
2/6/2012
Pred Forte for Inflammation of the Iris and Ciliary Body of the Eye
I've been using this product for 24 years to treat iritis. In my experience, it stings and burns like acid. Be prepared for the pain if you decide to use this treatment.
5Patient Review
6/29/2022
Pred Forte for Inflammation of the Iris - the Colored Part of the Eyeball
These drops have saved my eyeballs on two separate occasions! They caused a slight increase in eye pressure but it was still within the limit. I took them like a champion and my eyes love them!
5Patient Review
7/17/2016
Pred Forte for Inflammation of the Iris and Ciliary Body of the Eye
I would recommend you consider all potential risks before taking this medication. It did help with the inflammation, but caused an infection that has now led to surgery being required to fix my lazy eye.
4.7Patient Review
1/9/2022
Pred Forte for Inflammation of the Eye
I used Pred Forte Eyedrops for a week after some perfume got in my eye and caused inflammation. I gradually stopped using it as per the doctor's direction, and for 2 days it was good. But then the inflammation came back. Now I have to use this over a month, gradually reducing the number of times I use it each day. Make sure you use some drops like Refresh Tears along with it to avoid burning/ irritation.
4.3Patient Review
2/28/2011
Pred Forte for Inflammation of the Eye Following Surgery
4Patient Review
3/28/2012
Pred Forte for Inflammation of the Eye Following Surgery
I had cornea transplants in both eyes and have been taking this six times a day as prescribed. Unfortunately, I've experienced several negative side effects like swelling of the face and eyes, vomiting, and blurred vision. I'm also now suffering from much worse allergies than before. I've brought this up to my doctors but they don't believe me.
4Patient Review
12/15/2011
Pred Forte for Severe Inflammation of the Eye
I was prescribed this after having PRK Lasik. I had terrible reactions to this medication, feeling depressed, high heart rate and major anxiety. I asked to be taken off of it right away!
4Patient Review
4/13/2021
Pred Forte for Inflammation of the Iris and Ciliary Body of the Eye
I've been using these drops for a few weeks now and I'm starting to feel like I might be too dependent on them. My vision has become quite blurry, to the point where I have difficulty seeing screens. However, it has been effective in reducing pain and inflammation.
3.3Patient Review
2/18/2013
Pred Forte for Inflammation of the Eye Following Surgery
I had PRK surgery and started taking this medication. However, I began to feel dizzy each day, so I stopped after a week even though the doctor wanted me to take it for a month. If you experience side effects like this, listen to your body and stop taking the medication immediately.
3Patient Review
5/12/2014
Pred Forte for Inflammation of the Eye
I developed some eye problems and impotence after just three months of using this treatment.
2.7Patient Review
6/23/2013
Pred Forte for Severe Inflammation of the Eye
After a month of taking this drug following a glaucoma operation, my anxiety has flared up from time to time. I'm not sure if it's the medication or if it's residual trauma from the pain of glaucoma, but I trust my doctors and will continue to take it as directed.
2.3Patient Review
9/28/2020
Pred Forte for Inflammation of the Eye Following Surgery
Following Lasik, I used this treatment to target epithelial cells. It did the job, but came with a whole host of terrible side effects: anxiety, depression, feeling pressure in my face, and exhaustion.
2.3Patient Review
5/11/2012
Pred Forte for Inflammation of the Eye Following Surgery
I've found that my blood sugar has increased since I began using this medication.
1.7Patient Review
4/27/2011
Pred Forte for Inflammation of the Eye Following Surgery
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Patient Q&A Section about pred forte

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How long should I use Pred Forte?

"Use eye drops for no longer than one week unless directed by a doctor. Prolonged use can cause issues within your eye."

Answered by AI

Is Pred Forte a steroid?

"Prednisolone, brand name Pred Forte, is a steroid medication used to treat eye conditions characterized by inflammation or sensitivity to light. It is effective in controlling allergic reactions and reducing swelling."

Answered by AI

What are the side effects of Pred Forte eye drops?

"Using this medication may cause burning, stinging, or itching in the eyes for 1-2 minutes. You may also have temporary cloudy vision, increased sensitivity to light, or visual disturbances such as blurry vision. Some people feel like there is something in their eye after using this medication. Allergic reactions are also a possible side effect."

Answered by AI

What is Pred Forte used for?

"PRED FORTE is used to treat eye inflammation in adults. Short-term use of this medication can help to reduce the burning, redness, swelling, and irritation that is associated with inflammation of the eye caused by chemicals, heat, radiation, allergies, or foreign objects."

Answered by AI

Clinical Trials for Pred Forte

Image of UConn Health in Farmington, United States.

Cognitive Remediation for Memory and Thinking Difficulties

18+
All Sexes
Farmington, CT
The goal of this clinical trial is to determine if a neuroscience-based computerized cognitive remediation ("brain training") program can treat neurocognitive dysfunction (i.e., memory or thinking difficulties) that emerges in some older adults following a viral infection. The main questions it aims to answer are: * Does computerized cognitive remediation improve cognitive performance and day-to-day functioning in older adults with postviral neurocognitive dysfunction? * Will treatment effects be maintained over time, leading to better long term cognitive outcomes? * Does the treatment lead to reductions in blood-based markers of inflammation as a potential mechanism of cognitive symptom improvement? * Can the treatment be optimized and refined based on feedback from participants to improve user (patient) experience? Researchers will compare the computerized cognitive remediation program to an active computer-based control condition (alternative computer activities) to see if the computerized cognitive remediation program works to treat postviral neurocognitive dysfunction. Participation takes approximately 43-48 hours over 7 months, with most activities (40-46 hours) completed within the first 7-8 weeks, including: * Initial intake visit: Eligibility confirmation (\~2-3 hours) * Computer activities: About 5 hours per week for \~6 weeks (total \~30 hours) completed on a computer tablet provided by the study and loaned to participants for use during the treatment phase * Weekly remote check-in meetings: \~30 minutes each during treatment * Blood draws: Two sessions (before and after treatment), \~20-30 minutes each * Three research visits: Pre-treatment, post-treatment, and 6-month follow-up (\~2-3 hours each, including assessments of cognitive, emotional, and daily functioning)
Waitlist Available
Has No Placebo
UConn HealthCutter Lindbergh, Ph.D.
Image of Department of Nutritional Sciences in Storrs, United States.

Freeze-dried Grape Powder for Healthy Aging

50 - 75
All Sexes
Storrs, CT
The purpose of this study is to investigate the effects of consuming grape powder on immune profiles in healthy middle- and older-aged individuals. Specifically, the investigators are interested in evaluating the potential effects of grapes in influencing markers of immune function, inflammation, and metabolism that are known to change with aging. Grapes contain several nutrients and antioxidant polyphenols such as resveratrol, quercetin, vitamin K and fiber, which are known to promote heart and immune health. However, the effects of grapes on altering immune profiles within the context of aging is not well understood. Therefore, this study will explore how daily grape consumption impacts certain markers of immunity in healthy middle- and older-aged adults. The main study procedures include consumption of a freeze-dried grape powder and control powder (which tastes the same but has none of the grape compounds that are being studied) mixed with water as a beverage on a daily basis for 4 weeks each. The investigators will additionally ask that participants avoid eating grapes and certain other antioxidant/grape-related foods and beverages throughout the 13-week study. Participants will additionally be asked to complete surveys about their diet, physical activity, and medical history, as well as provide blood samples and body weight measures throughout the course of the study. Participation in the study is expected to last about 6.25 hours over the course of 13 weeks and will include 7 visits.
Recruiting
Paid Trial
Department of Nutritional Sciences
Have you considered Pred Forte clinical trials? We made a collection of clinical trials featuring Pred Forte, we think they might fit your search criteria.Go to Trials
Image of School of Public Health in Bloomington, United States.

High Salt Intake for High Blood Pressure

60 - 85
All Sexes
Bloomington, IN
Most Americans consume excess dietary salt based on the recommendations set by the American Heart Association and Dietary Guidelines for Americans. High dietary salt impairs blood pressure control by affecting systemic blood vessels and the kidneys. These changes contribute to excess salt consumption being associated with increased risk for chronic kidney disease and cardiovascular disease, the leading cause of death in America. Salt is particularly deleterious in older adults who are more likely to exhibit salt-sensitive hypertension. However, salt consumption remains high in the United States. Thus, there is a critical need for strategies to counteract the effects of high dietary salt as consumption is likely not going to decrease. One promising option is ketones, metabolites that are produced in the liver during prolonged exercise and very low-calorie diets. While exercise and low-calorie diets are beneficial, not many people engage in these activities. Limited evidence indicates that ketone supplements improve cardiovascular health in humans. Additionally, published rodent data indicates that ketone supplements prevent high salt-induced increases in blood pressure, blood vessel dysfunction, and kidney injury. Our human pilot data also indicates that high dietary salt reduces intrinsic ketone production, but it is unclear whether ketone supplementation confers humans' protection against high salt similar to rodents. Therefore, the investigators seek to conduct a short-term high-dietary salt study to determine whether ketone supplementation prevents high dietary salt from eliciting increased blood pressure, blood vessel dysfunction, and kidney injury/impaired blood flow. The investigators will also measure inflammatory markers in blood samples and isolate immune cells that control inflammation. Lastly, the investigators will also measure blood ketone concentration and other circulating metabolites that may be altered by high salt, which could facilitate novel therapeutic targets to combat high salt.
Recruiting
Has No Placebo
School of Public Health
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Biophoton Therapy for Stem Cell Proliferation

18 - 70
All Sexes
Tampa, FL
Study Objective The purpose of this clinical study is to evaluate if biophoton therapy, delivered by Tesla BioHealing® Biophoton Generators (Biophotonizer), can increase self-grown stem cells naturally. Study Design This is a randomized, double-blinded, placebo-controlled intervention clinical study to assess the effectiveness of biophoton therapy in impacting stem cells. Approximately 46 volunteers who want to increase self-grown stem cells will participate in the study. Study Randomization The biostatistician will prepare a randomization schedule including a serial of subject numbers. A subject number will be randomly assigned to each study participant, which will assign them to either the control group or the treatment group. Other than the Informed Consent Form (ICF), all study information will be recorded by using the subject number. The Principal Investigator, study physicians, study nurse, data-entry specialists, and biostatisticians, as well as the participants, will be blinded about who received which product during the first two weeks of study participation.
Recruiting
Online Trial
Tesla MedBed at Tampa-FL (+1 Sites)James Z Liu, MD, PhD
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Physical Activity for Delayed Onset Muscle Soreness

18 - 35
All Sexes
Toronto, Canada
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS). DOMS is characterized by muscle pain and tenderness that typically resolves within a week. While the precise cause of DOMS is unknown, there is growing evidence implicating damage to the connective tissue that surrounds our muscle fibers and is related to a small amount of inflammation. This inflammation is a normal part of our body's ability to recovery from injuries and may be visualized through the use of ultrasound technology. A variety of recovery techniques have been proposed that may help with the recovery of DOMS such as massage and electrical muscle stimulation, but these are not always accessible. Therefore, we are interested in investigating whether the number of daily steps can affect how you experience DOMS.
Waitlist Available
Has No Placebo
Goldring Center for High Performance Sport
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Image of University of California, San Diego Altman Clinical and Translational Research Institute in San Diego, United States.

Mediterranean Diet for Inflammation Post-Colonoscopy

18+
All Sexes
San Diego, CA
This study aims to investigate the impact of various healthy diets, specifically a modified plant-based Mediterranean diet, on the gut microbiome and overall well-being post-colonoscopy. The investigators hypothesize that certain diets can positively influence gut bacteria, reducing inflammation and enhancing metabolic signals. To explore this, they will utilize metagenomic testing on stool samples to analyze the DNA of gut microorganisms. Additionally, they will conduct immune profiling on serum samples and perform metabolomic analysis to comprehensively evaluate the diet-induced changes in immune response and metabolic pathways. This multi-faceted approach will help them understand how dietary changes affect the composition and function of the gut microbiome, immune function, and overall metabolism.
Recruiting
Has No Placebo
University of California, San Diego Altman Clinical and Translational Research Institute
Have you considered Pred Forte clinical trials? We made a collection of clinical trials featuring Pred Forte, we think they might fit your search criteria.Go to Trials
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