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What is Pred Forte
Prednisolone acetateThe Generic name of this drug
Treatment SummaryPrednisolone acetate is a medication used to treat inflammation and other related conditions. It contains prednisolone, a steroid, combined with an acetate group. Prednisolone acetate was approved by the FDA in 1955.
Blephamideis the brand name
Pred Forte Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Blephamide
Prednisolone acetate
1961
39
Approved as Treatment by the FDA
Prednisolone acetate, also known as Blephamide, is approved by the FDA for 3 uses including Inflammation and Organ Transplantation .Inflammation
Organ Transplantation
Inflammatory Conditions
Helps manage Inflammatory Conditions
Effectiveness
How Pred Forte Affects PatientsPrednisolone acetate is a type of corticosteroid drug that blocks the body's pro-inflammatory signals and encourages anti-inflammatory signals. Its effects wear off quickly, with a half life of 2-3 hours. Corticosteroids can be taken in doses much higher than the body's natural production, and this has a wide therapeutic window. Taking corticosteroids can have side effects such as suppression of the hypothalamic-pituitary-adrenal axis and increased risk of infections, so patients should be aware of these risks.
How Pred Forte works in the bodyCorticosteroids reduce swelling and stop white blood cells from flowing to sites of inflammation. This is done by changing the expression of certain genes. Corticosteroids also prevent cells from dying and stop the formation of chemicals that cause inflammation. Lower doses of corticosteroids help with inflammation, while higher doses weaken your immune system. Very high doses of corticosteroids can cause too much sodium and too little potassium in the body.
When to interrupt dosage
The advised measure of Pred Forte is contingent upon the identified disorder, including Ocular Infections, Irritations and Inflammations, Ocular Inflammation and Inflammatory Conditions. The sum of dosage differs, according to the technique of delivery (e.g. Ophthalmic or Solution / drops - Ophthalmic) featured in the table below.Condition
Dosage
Administration
Inflammation
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
Ocular Inflammation
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
Ocular Infections, Irritations and Inflammations
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
Organ Transplantation
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
Inflammatory Conditions
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
superficial ocular infections
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
Eye Infections, Bacterial
0.002 mg/mg, , 10.0 mg, 10.0 mg/mL, 2.0 mg/mL, 1.2 mg/mL, 0.2 %, 1.0 %, 0.12 %, 0.006 mg/mg, 0.5 %, 1.25 mg/mL, 1.0 mg/mL, 10.0 mg/mg, 1.25 mg, 5.0 mg/mL, 16.7 mg/mL, 0.005 mg/mg
, Ophthalmic, Ointment, Ointment - Ophthalmic, Oral, Suspension, Suspension - Oral, Suspension / drops, Suspension / drops - Ophthalmic, Suspension - Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Solution, Solution - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit, Kit - Ophthalmic
Warnings
Pred Forte has one contraindication and should not be ingested if you are suffering from any of the conditions detailed in the following table.Pred Forte ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Prednisolone Acetate may interact with Pulse Frequency
Common Pred Forte Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Prednisolone acetate.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Prednisolone acetate.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Prednisolone acetate.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Prednisolone acetate.
Aminophylline
Major
The metabolism of Aminophylline can be increased when combined with Prednisolone acetate.
Pred Forte Toxicity & Overdose RiskThe lowest toxic dose of prednisolone acetate in mice is 1680mg/kg. People who overdose on this drug may experience more severe side effects of corticosteroids. If the overdose occurred recently, treatment may include stomach pumping or inducing vomiting. For long-term overdose, doctors may reduce the dose or have patients take the drug every other day. An overdose through the eyes is not likely to cause problems.
Pred Forte Novel Uses: Which Conditions Have a Clinical Trial Featuring Pred Forte?
At present, 189 active trials are exploring the potential of Pred Forte in alleviating Inflammation, Inflammatory Conditions and Superficial Ocular Infections.Condition
Clinical Trials
Trial Phases
Inflammation
170 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Early Phase 1, Phase 3, Phase 4
Inflammatory Conditions
1 Actively Recruiting
Phase 2
Ocular Inflammation
3 Actively Recruiting
Phase 2, Phase 4, Phase 3
Organ Transplantation
0 Actively Recruiting
Eye Infections, Bacterial
0 Actively Recruiting
superficial ocular infections
0 Actively Recruiting
Ocular Infections, Irritations and Inflammations
0 Actively Recruiting
Pred Forte Reviews: What are patients saying about Pred Forte?
5Patient Review
7/22/2012 I've been on this medication for a few weeks now, three times a day. I'm sure it's effective, but the taste is absolutely vile. It lingers in your mouth for hours afterwards and makes my stomach hurt. I'll be calling the doctor on Monday morning to discuss other options.
5Patient Review
2/6/2012 I've been using this product for 24 years to treat iritis. In my experience, it stings and burns like acid. Be prepared for the pain if you decide to use this treatment.
5Patient Review
6/29/2022 These drops have saved my eyeballs on two separate occasions! They caused a slight increase in eye pressure but it was still within the limit. I took them like a champion and my eyes love them!
5Patient Review
7/17/2016 I would recommend you consider all potential risks before taking this medication. It did help with the inflammation, but caused an infection that has now led to surgery being required to fix my lazy eye.
4.7Patient Review
1/9/2022 I used Pred Forte Eyedrops for a week after some perfume got in my eye and caused inflammation. I gradually stopped using it as per the doctor's direction, and for 2 days it was good. But then the inflammation came back. Now I have to use this over a month, gradually reducing the number of times I use it each day. Make sure you use some drops like Refresh Tears along with it to avoid burning/ irritation.
4.3Patient Review
2/28/20114Patient Review
3/28/2012 I had cornea transplants in both eyes and have been taking this six times a day as prescribed. Unfortunately, I've experienced several negative side effects like swelling of the face and eyes, vomiting, and blurred vision. I'm also now suffering from much worse allergies than before. I've brought this up to my doctors but they don't believe me.
4Patient Review
12/15/2011 I was prescribed this after having PRK Lasik. I had terrible reactions to this medication, feeling depressed, high heart rate and major anxiety. I asked to be taken off of it right away!
4Patient Review
4/13/2021 I've been using these drops for a few weeks now and I'm starting to feel like I might be too dependent on them. My vision has become quite blurry, to the point where I have difficulty seeing screens. However, it has been effective in reducing pain and inflammation.
3.3Patient Review
2/18/2013 I had PRK surgery and started taking this medication. However, I began to feel dizzy each day, so I stopped after a week even though the doctor wanted me to take it for a month. If you experience side effects like this, listen to your body and stop taking the medication immediately.
3Patient Review
5/12/2014 I developed some eye problems and impotence after just three months of using this treatment.
2.7Patient Review
6/23/2013 After a month of taking this drug following a glaucoma operation, my anxiety has flared up from time to time. I'm not sure if it's the medication or if it's residual trauma from the pain of glaucoma, but I trust my doctors and will continue to take it as directed.
2.3Patient Review
9/28/2020 Following Lasik, I used this treatment to target epithelial cells. It did the job, but came with a whole host of terrible side effects: anxiety, depression, feeling pressure in my face, and exhaustion.
2.3Patient Review
5/11/2012 I've found that my blood sugar has increased since I began using this medication.
1.7Patient Review
4/27/2011Patient Q&A Section about pred forte
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How long should I use Pred Forte?
"Use eye drops for no longer than one week unless directed by a doctor. Prolonged use can cause issues within your eye."
Answered by AI
Is Pred Forte a steroid?
"Prednisolone, brand name Pred Forte, is a steroid medication used to treat eye conditions characterized by inflammation or sensitivity to light. It is effective in controlling allergic reactions and reducing swelling."
Answered by AI
What are the side effects of Pred Forte eye drops?
"Using this medication may cause burning, stinging, or itching in the eyes for 1-2 minutes. You may also have temporary cloudy vision, increased sensitivity to light, or visual disturbances such as blurry vision. Some people feel like there is something in their eye after using this medication. Allergic reactions are also a possible side effect."
Answered by AI
What is Pred Forte used for?
"PRED FORTE is used to treat eye inflammation in adults. Short-term use of this medication can help to reduce the burning, redness, swelling, and irritation that is associated with inflammation of the eye caused by chemicals, heat, radiation, allergies, or foreign objects."
Answered by AI