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What is Consensi
CelecoxibThe Generic name of this drug
Treatment SummaryCelecoxib is a medication used to treat arthritis pain and reduce precancerous polyps in the colon. It is a type of NSAID (nonsteroidal anti-inflammatory drug) that has a lower risk of causing gastrointestinal bleeding than other NSAIDs. It was approved by the FDA in 1998 and is sold under the brand name Celebrex. In addition to its use as a pain reliever, celecoxib has also been studied as a potential cancer treatment.
Celebrexis the brand name
Consensi Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Celebrex
Celecoxib
1998
379
Approved as Treatment by the FDA
Celecoxib, otherwise called Celebrex, is approved by the FDA for 6 uses which include Ankylosing Spondylitis and Rheumatoid Arthritis, Juvenile .Ankylosing Spondylitis
Helps manage Ankylosing Spondylitis (AS)
Rheumatoid Arthritis, Juvenile
Helps manage Rheumatoid Arthritis, Juvenile
Acute Pain
Helps manage Pain, Acute
Rheumatoid Arthritis
Helps manage Rheumatoid Arthritis
Primary Dysmenorrhoea
Helps manage Primary Dysmenorrhoea
Osteoarthritis (OA)
Helps manage Osteoarthritis (OA)
Effectiveness
How Consensi Affects PatientsCelecoxib works by blocking the cyclooxygenase 2 (COX-2) enzyme, reducing pain and inflammation. Although it is considered to be safer than other NSAIDs when it comes to gastrointestinal bleeding, there is still a risk of bleeding. Studies have shown that celecoxib is associated with a risk of cardiovascular thrombotic events (such as heart attack or stroke) similar to other NSAIDs. However, the benefits of taking celecoxib are thought to outweigh the risks. The lowest possible dose of celecoxib has been found to be as safe as moderate doses of naproxen and ibupro
How Consensi works in the bodyCelecoxib is different from other drugs used to reduce pain and inflammation, because it only targets one type of enzyme, COX-2. By blocking this enzyme, celecoxib reduces the production of substances that cause pain and inflammation. Unlike other drugs like this, celecoxib is less likely to cause ulcers in the stomach. Celecoxib also has anti-cancer properties, as it binds to a protein involved in tumor progression, and blocks a chemical pathway that helps tumors grow. However, celecoxib can increase the risk of clotting because it reduces the production of a substance that prevents platelets from clumping together.
When to interrupt dosage
The advised dosage of Consensi is dependent on the detected condition, such as Ankylosing Spondylitis, Primary Dysmenorrhoea and Rheumatoid Arthritis. The quantity of dosage shifts, as per the technique of delivery (e.g. Tablet - Oral or Oral) noted in the table beneath.Condition
Dosage
Administration
Pain
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Therapeutic procedure
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Acute Pain
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Rheumatoid Arthritis, Juvenile
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Ankylosing Spondylitis
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Rheumatoid Arthritis
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Osteoarthritis (OA)
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Primary Dysmenorrhoea
50.0 mg, , 100.0 mg, 200.0 mg, 400.0 mg, 25.0 mg/mL, 56.0 mg, 120.0 mg/mL
, Oral, Capsule, Capsule - Oral, Oral; Topical, Kit - Oral; Topical, Kit, Kit - Oral, Tablet - Oral, Tablet, Solution, Solution - Oral, Liquid - Oral, Liquid
Warnings
Consensi has four contraindications and should not be used if you are experiencing any of the conditions outlined in the following table.Consensi ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Celecoxib may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Celecoxib may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Celecoxib may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Celecoxib may interact with Pulse Frequency
Common Consensi Drug Interactions
Drug Name
Risk Level
Description
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Celecoxib.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Celecoxib.
Cyclopentamine
Major
The risk or severity of adverse effects can be increased when Celecoxib is combined with Cyclopentamine.
Fluorouracil
Major
The metabolism of Fluorouracil can be decreased when combined with Celecoxib.
Fosphenytoin
Major
The metabolism of Fosphenytoin can be decreased when combined with Celecoxib.
Consensi Toxicity & Overdose RiskPeople should not take celecoxib if they have reduced kidney or liver function, as this may lead to increased concentrations of the drug in their bloodstream, causing toxicity. Symptoms of overdose may include difficulty breathing, loss of consciousness, gastrointestinal bleeding, high blood pressure, kidney failure, nausea, sluggishness, stomach pain, and vomiting. As serious bleeding can occur without warning signs or symptoms, patients should be monitored for signs of bleeding. Treatment for celecoxib overdose includes inducing vomiting or administering activated charcoal within 4 hours of ingestion. Diuretics, urinary alkalinization, dialysis, or hemoperfusion may not be effective due to
Consensi Novel Uses: Which Conditions Have a Clinical Trial Featuring Consensi?
102 active trials are being conducted to assess the efficacy of Consensi in alleviating symptoms of Rheumatoid Arthritis, Juvenile Rheumatoid Arthritis and Primary Dysmenorrhoea.Condition
Clinical Trials
Trial Phases
Therapeutic procedure
0 Actively Recruiting
Osteoarthritis (OA)
0 Actively Recruiting
Ankylosing Spondylitis
2 Actively Recruiting
Phase 3, Not Applicable
Pain
0 Actively Recruiting
Acute Pain
21 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4, Phase 2, Phase 1
Rheumatoid Arthritis
61 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Primary Dysmenorrhoea
2 Actively Recruiting
Phase 4, Not Applicable
Rheumatoid Arthritis, Juvenile
4 Actively Recruiting
Not Applicable, Phase 3
Consensi Reviews: What are patients saying about Consensi?
5Patient Review
8/24/2020 Just a heads up that anyone can write a review for this drug, so please be aware of possible fake reviews.
5Patient Review
6/22/2020 I'm very pleased with Consensi so far. I'm 65 and knee pain had been severely limiting my ability to walk, which is a big part of my life. Within the first month of use, I noticed a significant reduction in pain. I hope it continues to be effective!
5Patient Review
8/24/2020 This product really helped me to make it through the day. It's the best one I've tried.
5Patient Review
6/3/20205Patient Review
6/10/2020 I'm feeling a lot better now. This pill was great!
Patient Q&A Section about consensi
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the drug amlodipine used for?
"Amlodipine is a medication used to treat hypertension, or high blood pressure. Hypertension puts extra strain on the heart and arteries, and can eventually lead to heart and artery damage if left unchecked."
Answered by AI
What is Consensi used for?
"Consensi is a medication that can be prescribed to adults who need treatment for high blood pressure, or who need to lower their blood pressure. Additionally, this medication can be prescribed to those who need help managing the signs and symptoms of osteoarthritis."
Answered by AI
Is amlodipine a NSAID drug?
"NSAIDs treat pain and inflammation.
Amlodipine helps improve blood flow by relaxing blood vessels. This in turn helps to prevent strokes, heart attacks, and kidney problems. Celecoxib is a pain reliever and anti-inflammatory medication."
Answered by AI
What is the major side effect of celecoxib?
"The use of NSAIDs such as celecoxib may lead to ulcers, bleeding, or holes in the stomach or intestine. These problems can occur at any time during treatment, without any warning symptoms, and can be fatal."
Answered by AI