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Mobile Video DOT for Heart Transplant Medication Adherence

N/A
Waitlist Available
Led By Dipankar Gupta, MD
Research Sponsored by University of Florida
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Participants are 10-21 years of age
Participants have received a heart transplant and are followed by participating pediatric heart transplant centers
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Study Summary

This trial will test an app to help kids with heart transplants take their medicine, to improve their health and reduce hospital visits, graft failure and mortality.

Who is the study for?
This trial is for heart transplant recipients aged 10-21 who speak English or Spanish, have a history of medication nonadherence, and own or can access a smartphone. They must be monitored by participating centers and willing to use an app. Those with cognitive impairments cannot join.Check my eligibility
What is being tested?
The study tests the eMocha DOT (Directly Observed Therapy) mobile video intervention aimed at improving medication adherence in young heart transplant patients to reduce rejection episodes and improve survival rates.See study design
What are the potential side effects?
Since this trial focuses on monitoring medication adherence through a mobile app rather than testing new medications, there are no direct side effects from the intervention itself.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I am between 10 and 21 years old.
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I have had a heart transplant and am under care at a pediatric heart transplant center.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Medication adherence based on medication level variability index

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: eMocha interventionExperimental Treatment1 Intervention
Adolescent patients randomized to the use of asynchronous mobile video directly observed therapy (DOT) intervention (eMocha DOT app)
Group II: Standard of careActive Control1 Intervention
Adolescent patients who continue enhanced goal-setting standard of care

Find a Location

Who is running the clinical trial?

emocha Mobile Health, Inc.OTHER
2 Previous Clinical Trials
236 Total Patients Enrolled
University of FloridaLead Sponsor
1,333 Previous Clinical Trials
714,491 Total Patients Enrolled
National Heart, Lung, and Blood Institute (NHLBI)NIH
3,814 Previous Clinical Trials
47,290,775 Total Patients Enrolled

Media Library

DOT intervention Clinical Trial Eligibility Overview. Trial Name: NCT05732779 — N/A
Heart Transplant Rejection Research Study Groups: eMocha intervention, Standard of care
Heart Transplant Rejection Clinical Trial 2023: DOT intervention Highlights & Side Effects. Trial Name: NCT05732779 — N/A
DOT intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT05732779 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are any individuals under the age of 25 being considered for participation in this experiment?

"Those that wish to join this medical trial must be between the ages of 10 and 21. For younger children (under 18) there are 6 studies available, while those over 65 can access 26 different experiments."

Answered by AI

Are any additional participants currently being sought for this research?

"This clinical trial, which first appeared on April 1st 2023 is not presently enlisting participants. However, at the moment there are 32 other medical trials actively recruiting patients."

Answered by AI

To whom is this clinical experiment available for participation?

"This clinical trial is seeking to enrol a total of 100 minors aged between 10 and 21 who have undergone heart transplantation and are currently experiencing rejection. In addition, participants must possess an MLVI score higher than 2.0 over the past year, be either English- or Spanish-speaking, own a smartphone or other device with access to the mobile app, as well as be willing to accept information through it."

Answered by AI
~67 spots leftby Mar 2025