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Focused Ultrasound

Transcranial Focused Ultrasound for Dementia

N/A
Waitlist Available
Led By Sheldon E Jordan, M.D.
Research Sponsored by Neurological Associates of West Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
CDR stage of at least 0.5 (mild cognitive impairment)
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up after final ultrasound (8 weeks from baseline)
Awards & highlights

Study Summary

This trial will study the effects of transcranial ultrasound on patients with mild cognitive impairment or dementia. The goal is to see if it is safe and effective.

Who is the study for?
This trial is for people with mild cognitive impairment or early-stage dementia, evidenced by specific brain imaging markers. Participants must be able to give informed consent and lie still in a calm environment. Those with cognitive issues due to acute illness, scalp conditions, severe physical illnesses, major depression, or vascular dementia are excluded.Check my eligibility
What is being tested?
The study tests the safety and initial effectiveness of transcranial focused ultrasound as a treatment for neurodegenerative dementias like Alzheimer's and Parkinson's disease over an extended period.See study design
What are the potential side effects?
While not explicitly listed here, potential side effects may include discomfort at the site of ultrasound application, headache, or temporary changes in mood or cognition due to the intervention.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
Select...
I have mild memory or thinking problems.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~after final ultrasound (8 weeks from baseline)
This trial's timeline: 3 weeks for screening, Varies for treatment, and after final ultrasound (8 weeks from baseline) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Quick Dementia Rating Scale
Secondary outcome measures
Montreal Cognitive Assessment (MoCA)
Quick Dementia Rating Scale (QDRS)
Repeatable Battery Assessment for Neuropsychological Status (RBANS)

Trial Design

1Treatment groups
Experimental Treatment
Group I: TreatmentExperimental Treatment1 Intervention
All patients enrolled will receive transcranial focused ultrasound. Target location is dependent on patient condition.

Find a Location

Who is running the clinical trial?

Neurological Associates of West Los AngelesLead Sponsor
25 Previous Clinical Trials
3,860 Total Patients Enrolled
Sheldon E Jordan, M.D.Principal InvestigatorNeurology Management Associates
2 Previous Clinical Trials
57 Total Patients Enrolled

Media Library

Transcranial Focused Ultrasound (Focused Ultrasound) Clinical Trial Eligibility Overview. Trial Name: NCT04250376 — N/A
Parkinson's Disease Research Study Groups: Treatment
Parkinson's Disease Clinical Trial 2023: Transcranial Focused Ultrasound Highlights & Side Effects. Trial Name: NCT04250376 — N/A
Transcranial Focused Ultrasound (Focused Ultrasound) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04250376 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are aged individuals over the age of 70 able to partake in this experiment?

"This medical study is open to patients aged 45 or over, up until 93 years of age."

Answered by AI

What specific demographic should be recruited to join this trial?

"Those with Parkinson's disease aged between 45 and 93 are eligible to be admitted into this trial, which is taking a total of 100 participants."

Answered by AI

Are new participants currently being enrolled in this experiment?

"Clinicaltrials.gov states that this particular study is not presently onboarding participants; it was initially posted on November 27th 2017 and its most recent update occurred August 30th 2021. There are, however, 1627 other clinical trials actively searching for volunteers at the moment."

Answered by AI
~10 spots leftby Dec 2024