Transcranial Focused Ultrasound for Dementia
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial is testing a treatment that uses sound waves aimed at specific brain areas to help patients with memory and cognitive issues. The goal is to see if this method is safe and effective for people with mild cognitive impairment or dementia. The therapy has been shown to be effective and safe in animal models of Alzheimer's disease and vascular dementia, with previous trials indicating a tendency to suppress cognitive impairment.
Who Is on the Research Team?
Sheldon E Jordan, M.D.
Principal Investigator
Neurology Management Associates
Are You a Good Fit for This Trial?
This trial is for people with mild cognitive impairment or early-stage dementia, evidenced by specific brain imaging markers. Participants must be able to give informed consent and lie still in a calm environment. Those with cognitive issues due to acute illness, scalp conditions, severe physical illnesses, major depression, or vascular dementia are excluded.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive transcranial focused ultrasound treatment aimed at the hippocampus or the putamen and substantia nigra, depending on the condition. Treatment includes 8 sessions of focused ultrasound.
Follow-up
Participants are monitored for safety and effectiveness after treatment using measures such as the Quick Dementia Rating Scale and Montreal Cognitive Assessment.
What Are the Treatments Tested in This Trial?
Interventions
- Transcranial Focused Ultrasound
Find a Clinic Near You
Who Is Running the Clinical Trial?
Neurological Associates of West Los Angeles
Lead Sponsor