Vaccination Games for Vaccine Education

Overseen By Nouran Ghonaim, BS

Age: < 18

Sex: Any

Trial Phase: Academic

Sponsor: Michigan State University

Disqualifiers: Non-English speakers, Prior HPV vaccine, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: 2

180 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial aims to boost confidence in the HPV vaccine among young people who have not yet received it. The focus is on using a game called "Vaccination Games" to educate kids and their parents about the HPV vaccine, compared to those who receive the usual information. It targets kids aged 11-14 who speak English, haven't had the HPV vaccine, and aren't in other HPV-related studies. Parents must also speak English, own a smartphone, and agree to participate.

As an unphased trial, this study provides a unique opportunity to contribute to innovative educational strategies that could increase vaccine uptake.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It seems focused on vaccine education, so it's unlikely that your medications will be affected.

What prior data suggests that the Vaccination Games are safe for promoting vaccine education?

Research has shown that using serious video games to promote HPV vaccination is safe. These games raise awareness and encourage discussions about the importance of the HPV vaccine. Studies have found that these educational games increase vaccination rates, especially among preteens. The games aim to normalize and simplify the vaccination process.

No negative effects have been reported from playing these educational games. They are well-received and focus on sharing information in a fun and engaging way. As an educational tool rather than a medical treatment, they present minimal safety concerns. This method has been tested before and has successfully increased vaccination rates without safety issues. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Vaccination Games intervention because it offers an innovative and engaging way to educate families about the HPV vaccine. Unlike standard educational methods, such as brochures or simple discussions, this approach uses interactive games to capture the attention of both parents and children. By making learning about vaccines fun and interactive, the hope is to improve understanding and increase vaccination rates. This fresh approach could address vaccine hesitancy by fostering a more informed and proactive attitude towards vaccinations.

What evidence suggests that the Vaccination Games are effective for promoting HPV vaccine confidence?

Research has shown that educational programs can increase HPV vaccination rates among young people. In 11 out of 14 studies, education led to higher vaccination rates. Other studies have also found that these programs can reduce vaccine-related concerns and encourage vaccination. For instance, students in schools with these programs were over three times more likely to receive the vaccine than those in other schools. This trial will compare the effectiveness of an educational game intervention, provided to participants in the HPV game group, to usual care, which involves no intervention. This suggests that educational games might effectively boost HPV vaccination rates among underserved youth. ^{4 6 7 8 9}

Who Is on the Research Team?

ANGELA C CHEN, PhD

Principal Investigator

Michigan State University

Are You a Good Fit for This Trial?

This trial is for parents or caregivers of children aged 11-14 who haven't had their first HPV or COVID-19 vaccine dose. The child must be able to speak and read English, and both the parent and child should be undecided or not planning on getting these vaccines.

Inclusion Criteria

I am between 11 and 14 years old.

Parent sample: Agree to participate in the research activities

Parent sample: Are the parent/caregiver of the participating child

Exclusion Criteria

Individuals who do not meet inclusion criteria

Individuals who refuse to provide consent/assent

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Intervention

Participants receive either the HPV game-based intervention or usual care

4 weeks

1 visit (in-person)

Follow-up

Participants are monitored for retention, satisfaction, and vaccine uptake

8 weeks

1 visit (virtual)

What Are the Treatments Tested in This Trial?

Interventions

• Vaccination Games

Trial Overview The study tests 'vaccination games' designed to increase confidence in vaccines among underserved youth. It focuses on improving uptake rates for the HPV and COVID-19 vaccines by engaging with children through educational gameplay.

How Is the Trial Designed?

Group I: HPV game group Experimental Treatment 1 Intervention

parent-child dyads receive HPV game intervention

Group II: Usual care Active Control 1 Intervention

parent-child dyads receive usual care (no intervention)

Who Is Running the Clinical Trial?

Michigan State University

Lead Sponsor

Trials

202

Recruited

687,000+

Citations

1. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC11433691/

The Effectiveness of Interventions Targeting Adolescents in ... HPV vaccine uptake increased following educational interventions in 11 out of the 14 studies that evaluated this outcome; studies presenting ...

2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC12513138/

Effects of an educational health promotion intervention to ... There is evidence that educational health promotion interventions could reduce vaccine hesitancy and have positive effects on HPV vaccine ...

3. sciencedirect.com sciencedirect.com/science/article/pii/S0264410X25006413

The effect of school-based interventions on HPV vaccine ... In-school education increased the likelihood of having HPV-vaccine-related discussions with friends (1.8 [1.2–2.6]). In-school vaccination ...

4. sciencedirect.com sciencedirect.com/science/article/pii/S1876034125002801

Implementation evaluation of a school- and primary care ... The PrevHPV national research program aimed to codevelop and evaluate an intervention including three components: 'education and motivation' of adolescents in ...

5. mdpi.com mdpi.com/2076-393X/13/9/894

Review of Human Papillomavirus Vaccination Programs in ... Students enrolled in the intervention school were >3.6 times more likely to get the HPV vaccine than students enrolled in the comparison schools.

6. clinicaltrials.gov clinicaltrials.gov/ct2/show/NCT04627298

Normalizing HPV Vaccination in Preteens With a Serious ... HPV vaccination initiation and completion data are collected from practices for both preteens who receive the game and a comparison group who do ...

7. games.jmir.org games.jmir.org/2020/4/e16883/

Pilot Randomized Controlled Trial - JMIR Serious Games HPV vaccination, especially for preteens aged 11 to 12 years, is effective in preventing the acquisition of HPV and HPV-associated cancers.

8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC5797321/

Developing a Serious Videogame for Preteens to Motivate ... Offering information and cues to action through a serious videogame for preteens may foster HPV vaccination awareness, information seeking, and communication.

9. mdpi.com mdpi.com/1648-9144/60/9/1550

The Effectiveness of Interventions Targeting Adolescents in ... HPV vaccine uptake increased following educational interventions in 11 out of the 14 studies that evaluated this outcome; studies presenting multicomponent ...