Supportive Services for Substance Use Disorders

(SRC Trial)

Overseen By David O Meltzer, MD, PhD

Age: 18+

Sex: Male

Trial Phase: Academic

Sponsor: University of Chicago

Disqualifiers: Females, Under 18, No acute needs

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: Immediate post-discharge period

15195 Participants Needed

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial tests a program to support men released from the Cook County Jail who face mental health or substance use challenges. The researchers aim to determine if an overnight stay at the Supportive Release Center (SRC) and assistance with community services can reduce re-arrest rates within a year. Participants will either receive usual care with service referrals during discharge or the new SRC services, which include an overnight stay, service linkages, and access to a nurse. Men leaving the jail who need and are interested in services are a good fit for this trial. As an unphased trial, this study provides a unique opportunity to access supportive services that could significantly improve the transition back into the community.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications.

What prior data suggests that the SRC is safe for individuals with substance use disorders?

Research shows that the Supportive Release Center (SRC) provides a safe environment for individuals leaving jail. This trial includes an overnight stay at the SRC, where participants can access community services and consult with a nurse. However, the articles reviewed did not provide specific safety information about overnight stays at the SRC.

This trial is labeled "Not Applicable" for a phase because it aims to improve service delivery rather than test a new drug or medical device. Such trials typically focus on enhancing care and support without introducing safety risks. The SRC is designed to assist with health, recovery, and reducing repeat offenses, emphasizing support over risky treatments. ^{1 2 3 4 5}

Why are researchers excited about this trial?

Researchers are excited about the Supportive Release Center (SRC) services for substance use disorders because they offer a novel approach that combines immediate support with community linkages. Unlike standard care, which typically involves only connecting individuals to community services after discharge, the SRC provides an overnight stay option and access to an Advanced Practice Nurse. This immediate, hands-on approach aims to stabilize individuals right at the point of release, potentially reducing the risk of relapse and improving long-term recovery outcomes. By offering both immediate and continued support, the SRC services could transform how we manage the critical transition period following release from incarceration.

What evidence suggests that the SRC services are effective for reducing arrests?

Research has shown that supportive services, like those in the Supportive Release Center (SRC) arm of this trial, effectively assist individuals with substance use and mental health issues. Participants in this trial may receive SRC services, including an overnight stay and follow-up care, to meet immediate needs and connect individuals to necessary resources. Studies have found that programs offering organized support and connections to community services lead to reduced substance use and fewer repeat offenses. This approach has been linked to better participation in treatment and a lower risk of relapse or re-arrest. Early findings suggest that focused support significantly aids the transition from jail to community life. ^{2 6 7 8 9}

Who Is on the Research Team?

David Meltzer, MD, PhD

Principal Investigator

University of Chicago

Harold Pollack, PhD

Principal Investigator

University of Chicago

Are You a Good Fit for This Trial?

This trial is for male adults leaving Cook County Jail who feel they need help with mental health, substance use disorders, or other vulnerabilities. They must be interested in receiving services to support their release.

Inclusion Criteria

You require additional services or assistance.

You are a male adult who has been released from Cook County Jail.

You want to receive the services being offered.

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants are randomized to either the Supportive Release Center (SRC) or usual care, with services including needs assessment, service linkages, and access to an Advanced Practice Nurse for those in the SRC group.

Immediate post-discharge period

Follow-up

Participants are monitored for re-arrests, emergency department visits, and engagement with homelessness services over a 365-day period.

365 days

Data Collection and Analysis

Data on arrests, healthcare utilization, and service engagement are collected and analyzed to evaluate the impact of the SRC intervention.

Ongoing throughout the follow-up period

What Are the Treatments Tested in This Trial?

Interventions

• APN Appointment
• SRC Overnight Stay
• TASC Service Linkages - Discharge Area Only
• TASC Services Linkages - SRC Onsite

Trial Overview The study tests if the Supportive Release Center (SRC) helps reduce arrests within a year after release by providing an environment to assess needs and link individuals to social services like medical care and treatment for substance abuse or mental health issues.

How Is the Trial Designed?

Group I: Supportive Release Center (Treatment) Experimental Treatment 4 Interventions

These individuals will receive SRC services: an overnight stay at the SRC, linkages to community-based services made at the SRC or in the discharge area of the CCJ if they choose not to visit the SRC facility, and access to an Advanced Practice Nurse. Individuals randomized on days Heartland Alliance Health recruits at SRC for non-SRC study are excluded from population. Receives: TASC Service Linkages - Discharge Area Only -OR- SRC Overnight Stay, TASC Services Linkages - SRC Onsite, APN Appointment

Group II: Usual Care (Control) Active Control 1 Intervention

Usual care. These individuals will receive linkages to community-based services only. These linkages will be made while in the Discharge Area of the Cook County Jail. Individuals randomized on days Heartland Alliance Health recruits at SRC for non-SRC study are excluded from population. Receives: TASC Service Linkages - Discharge Area Only

Who Is Running the Clinical Trial?

University of Chicago

Lead Sponsor

Trials

1,086

Recruited

844,000+

Center for the Advancement of Critical Time Intervention

Collaborator

Trials

2

Recruited

15,300+

Sheriff's Office of Cook County, Illinois

Collaborator

Trials

1

Recruited

15,200+

Robert R McCormick Foundation

Collaborator

Trials

1

Recruited

15,200+

Laura and John Arnold Foundation

Collaborator

Trials

13

Recruited

30,500+

Pritzker Family Foundation

Collaborator

Trials

3

Recruited

15,200+

Treatment Alternatives for Safe Communities Inc

Collaborator

Heartland Health Research Alliance

Collaborator

Trials

1

Recruited

2,600+

TASC INC

Collaborator

Trials

1

Recruited

15,200+

Heartland Health Outreach Inc

Collaborator

Trials

1

Recruited

15,200+

Published Research Related to This Trial

In a study involving 127 homeless individuals with substance use disorders, those receiving day treatment plus contingency management (DT+) were 2.1 times more likely to achieve positive treatment outcomes compared to those receiving only day treatment (DT).

The findings suggest that using diagnostic changes alongside traditional measures like drug toxicology and self-reports can enhance the assessment of treatment effectiveness in substance use disorder interventions.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Diagnostic compared with abstinence outcomes of day treatment and contingency management among cocaine-dependent homeless persons. Schumacher, JE., Milby, JB., Wallace, D., et al.[2022]

The study followed 149 homeless mothers over 18 months and found that those in residential substance abuse treatment had lower dropout rates compared to those in nonresidential services.

Both residential and nonresidential groups showed improvements in alcohol and drug issues and housing stability, indicating that residential placements can enhance engagement in treatment programs for homeless mothers.

NCBI (Pubmed)

pubmed.ncbi.nlm.nih.gov

Eighteen-month follow-up data on a treatment program for homeless substance abusing mothers. Smith, EM., North, CS., Fox, LW.[2022]

Citations

1. withpower.com withpower.com/trial/phase-substance-related-disorders-10-2017-749d7

Supportive Services for Substance Use Disorders (SRC Trial) ... SRC Overnight Stay will have tolerable side effects & efficacy for patients with Drug Addiction, Repeat Offending, Mental Health, Mental Health, Mental ...

2. ctv.veeva.com ctv.veeva.com/study/supportive-release-center-study

Supportive Release Center Study (SRC) - ClinicalTrials.Veeva The aim of the SRC is to identify individuals with mental illnesses, substance use disorders, and other vulnerabilities as they are released ...

3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov/articles/PMC4152944/

Substance Abuse Intensive Outpatient Programs In summary, study conclusions are consistent and similar—outcomes reflecting alcohol and drug use at follow-up show reductions in substance use and increases in ...

4. chapinhall.org chapinhall.org/wp-content/uploads/2023.11.7_Telehealth-Policy-Brief_final.pdf

An Evaluation of Telehealth for Opioid Use Disorders in a ... the only option to offering MOUDs helps people stay in treatment and potentially reduces the risk of overdosing upon release (Substance Abuse and Mental Health ...

5. kff.org kff.org/mental-health/a-look-at-substance-use-and-mental-health-treatment-facilities-across-the-u-s/

A Look at Substance Use and Mental Health Treatment ... This brief uses 2022 data from the National Substance Use and Mental Health Services Survey (N-SUMHSS), an annual survey sent to all ...

6. clinicaltrials.gov clinicaltrials.gov/study/NCT03616990?tab=history&a=3

Record History | ver. 3: 2023-05-09 | NCT03616990 This table shows all the versions of this study record arranged in order by submitted date. To view one version of the study record, click the submitted ...

7. tasc.org tasc.org/TascBlog/images/documents/Programs/SupportiveReleaseCenter-FactSheet.pdf

Supportive Release Center We help to increase health, reduce recidivism, and support recovery by providing case management, outpatient substance use disorder treatment, and other direct ...

8. reporter.nih.gov reporter.nih.gov/search/22ETxzroUEyh1C_i5IGvWA/project-details/10891513

RePORT ⟩ RePORTER We're sorry but RePORTER doesn't work properly without JavaScript enabled. Please enable it to continue.

9. nj.gov nj.gov/humanservices/dmhas/publications/federal/FY%202023%20Combined%20MHBG%20and%20SUPTRSBG%20App.pdf

New Jersey Center for Substance Abuse ... HBV vaccination, substance use disorder treatment, recovery support services and medical and mental health services ...