Betamethasone Sodium Phosphate

Iritis, Nephrotic Syndrome, Iridocyclitis + 90 more

Treatment

14 FDA approvals

20 Active Studies for Betamethasone Sodium Phosphate

Treatment for

Iritis

What is Betamethasone Sodium Phosphate

Betamethasone

The Generic name of this drug

Treatment Summary

Betamethasone is a long-acting steroid that reduces inflammation and suppresses the immune system. It is used topically to treat skin conditions like eczema, and can also be administered to treat various diseases like autoimmune disorders. Betamethasone is a powerful anti-inflammatory steroid with minimal effects on the body's salt balance.

Celestone Soluspan

is the brand name

image of different drug pills on a surface

Betamethasone Sodium Phosphate Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Celestone Soluspan

Betamethasone

1965

264

Approved as Treatment by the FDA

Betamethasone, otherwise known as Celestone Soluspan, is approved by the FDA for 14 uses like Lupus Erythematosus, Discoid and Lichen simplex chronicus .

Lupus Erythematosus, Discoid

Helps manage Discoid Lupus Erythematosus (DLE)

Lichen simplex chronicus

Helps manage Lichen simplex chronicus

Lichen Planus

Helps manage Lichen Planus (LP)

Psoriasis

Helps manage Psoriatic plaque

Granuloma Annulare

Helps manage granuloma annulare lesions

Keloids Scars

Helps manage Keloids Scars

granuloma annulare lesions

Helps manage granuloma annulare lesions

Lichen Planus (LP)

Helps manage Lichen Planus (LP)

Alopecia Areata (AA)

Helps manage Alopecia Areata (AA)

Psoriatic plaque

Helps manage Psoriatic plaque

Discoid Lupus Erythematosus (DLE)

Helps manage Discoid Lupus Erythematosus (DLE)

Neurodermatitis

Helps manage Lichen simplex chronicus

Alopecia Areata

Helps manage Alopecia Areata (AA)

Necrobiosis Lipoidica

Helps manage Necrobiosis lipoidica diabeticorum

Effectiveness

How Betamethasone Sodium Phosphate Affects Patients

Corticosteroids help to reduce inflammation and suppress the body's natural response to it. These drugs have a wide range of potential doses, and those taking them long-term need to be aware that their body can become less able to fight infection.

How Betamethasone Sodium Phosphate works in the body

Glucocorticoids like betamethasone reduce inflammation by stopping neutrophil death, cutting down on inflammatory signals, and increasing the production of anti-inflammatory molecules. They do this in two ways: the genomic pathway, which is slower but activates anti-inflammatory genes, and the nongenomic pathway, which is faster and manipulates cells like T-cells, platelets and monocytes.

When to interrupt dosage

The prescribed dosage of Betamethasone Sodium Phosphate is dictated by the diagnosed condition, including Ankylosing Spondylitis, Adrenal cortical hypofunctions and Post Surgical Ocular Inflammation. The amount of dosage relies upon the mode of application (e.g. Topical or Solution - Oral) indicated in the following table.

Condition

Dosage

Administration

Verrucous Lichen Planus (LP)

, 0.5 mg/mL, 0.001 mg/mg, 1.0 mg/mL, 0.0005 mg/mg, 0.000643 mg/mg, 0.00064 mg/mg, 0.64 mg, 0.00005 mg/mg, 0.0012 mg/mg, 3.0 mg/mL, 0.64 mg/mL, 0.005 mg/mg, 12.0 mg/mL, 0.05 %, 0.1 %, 0.12 %, 0.5 mg, 0.1 mg, 1.0 mg, 0.025 %, 0.1 mg/mL, 0.6 mg, 6.0 mg, 3.0 mg, 6.0 mg/mL, 7.0 mg/mL, 0.6 mg/mL, 0.643 mg/mL, 0.00061 mg/mg, 0.05 mg/mg, 0.064 mg/mg, 0.05 mg/mL, 0.00122 mg/mg

, Topical, Lotion, Lotion - Topical, Ointment, Ointment - Topical, Cream, Cream - Topical, Gel, Gel - Topical, Spray, metered, Spray, metered - Topical, Injection, suspension - Intra-articular; Intralesional; Intramuscular, Intra-articular; Intralesional; Intramuscular, Injection, suspension, Aerosol, foam, Aerosol, foam - Topical, Ointment, augmented - Topical, Ointment, augmented, Lotion, augmented - Topical, Lotion, augmented, Suspension, Suspension - Topical, Cream, augmented, Cream, augmented - Topical, Injection, solution, Injection, solution - Epidural; Intramuscular; Intraspinal; Intrathecal, Epidural; Intramuscular; Intraspinal; Intrathecal, Intramuscular, Injection, suspension - Epidural; Intramuscular; Intraspinal; Intrathecal, Injection, suspension - Intramuscular, Rectal, Enema - Rectal, Enema, Solution, Auricular (otic); Ophthalmic, Solution - Auricular (otic); Ophthalmic, Tablet, Tablet - Topical, Oral, Tablet - Oral, Tablet, effervescent - Oral, Tablet, effervescent, Liquid, Liquid - Auricular (otic); Ophthalmic, Liquid - Topical, Solution / drops, Solution / drops - Auricular (otic); Ophthalmic, Tablet, extended release - Oral, Ointment - Ophthalmic, Tablet, extended release, Ophthalmic, Spray, Spray - Topical, Suspension - Intra-articular; Intralesional; Intramuscular, Patch, Patch - Topical, Intra-articular; Intrabursal; Intradermal; Intramuscular, Suspension - Intra-articular; Intrabursal; Intradermal; Intramuscular, Kit, Cutaneous, Lotion - Cutaneous, Intra-articular; Intralesional; Intramuscular; Soft tissue, Injection, suspension - Intra-articular; Intralesional; Intramuscular; Soft tissue, Kit - Intra-articular; Intralesional; Intramuscular, Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular, Kit - Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular, Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular; Topical, Kit - Epidural; Infiltration; Intra-articular; Intralesional; Intramuscular; Topical, Kit - Topical, Infiltration; Intra-articular; Intralesional; Intramuscular; Perineural, Kit - Infiltration; Intra-articular; Intralesional; Intramuscular; Perineural, Infiltration; Intra-articular; Intralesional; Intramuscular; Perineural; Topical, Kit - Infiltration; Intra-articular; Intralesional; Intramuscular; Perineural; Topical, Solution - Oral, Solution - Topical

Rhinitis, Allergic

Anemia, Hemolytic

Giant Cell Arteritis

Congenital adrenal hyperplasia

Bursitis

acute nonspecific tenosynovitis

Dermatitis, Atopic

Lupus

Lichen Planus

Post Surgical Ocular Inflammation

Arthritis, Gouty

Leukemia

Iritis

Brain

Asthma

Lymphoma, Non-Hodgkin

Eczema

Multiple Sclerosis

Psoriasis

Warnings

Betamethasone Sodium Phosphate Contraindications

Condition

Risk Level

Notes

Pulse Frequency

Do Not Combine

There are 20 known major drug interactions with Betamethasone Sodium Phosphate.

Common Betamethasone Sodium Phosphate Drug Interactions

Drug Name

Risk Level

Description

2-Methoxyethanol

Major

The risk or severity of adverse effects can be increased when Betamethasone is combined with 2-Methoxyethanol.

9-(N-methyl-L-isoleucine)-cyclosporin A

Major

The risk or severity of adverse effects can be increased when Betamethasone is combined with 9-(N-methyl-L-isoleucine)-cyclosporin A.

Abatacept

Major

The risk or severity of adverse effects can be increased when Betamethasone is combined with Abatacept.

Abemaciclib

Major

The metabolism of Abemaciclib can be increased when combined with Betamethasone.

Abetimus

Major

The risk or severity of adverse effects can be increased when Betamethasone is combined with Abetimus.

Betamethasone Sodium Phosphate Toxicity & Overdose Risk

Taking too much glucocorticoid medication can lead to several serious side effects, such as cataracts, glaucoma, high blood pressure, fluid retention, high cholesterol, stomach ulcers, pancreatitis, muscle weakness, changes in mood, thinning skin, allergies, acne, excessive hair growth, weakened immune system, problems with calcium and phosphorus levels, increased blood sugar, and stunted growth. If an overdose occurs, the dose should be reduced or stopped and supportive treatment should be given.

image of a doctor in a lab doing drug, clinical research

Betamethasone Sodium Phosphate Novel Uses: Which Conditions Have a Clinical Trial Featuring Betamethasone Sodium Phosphate?

249 active clinical trials are currently in progress to ascertain the efficacy of Betamethasone Sodium Phosphate in the treatment of Eye Infection, Alopecia Areata (AA) and Verrucous Lichen Planus (LP).

Condition

Clinical Trials

Trial Phases

Lupus

64 Actively Recruiting

Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1

Rheumatoid Arthritis

56 Actively Recruiting

Not Applicable, Phase 3, Phase 1, Phase 2, Phase 4

Brain Tumor

60 Actively Recruiting

Not Applicable, Phase 1, Phase 4, Phase 2, Phase 3, Early Phase 1

Conjunctivitis

0 Actively Recruiting

Blepharoconjunctivitis

0 Actively Recruiting

Ulcerative Colitis

17 Actively Recruiting

Phase 3, Phase 2, Phase 1, Not Applicable, Phase 4

Eosinophilic Pneumonia

0 Actively Recruiting

Craniotomy

0 Actively Recruiting

Eye Injuries

0 Actively Recruiting

Dermatosis

0 Actively Recruiting

Sarcoidosis

10 Actively Recruiting

Phase 4, Phase 2, Not Applicable, Phase 3

Bacterial Infections

0 Actively Recruiting

Arthritis, Gouty

0 Actively Recruiting

Congenital adrenal hyperplasia

5 Actively Recruiting

Phase 3, Phase 1, Phase 2

Verrucous Lichen Planus (LP)

0 Actively Recruiting

Pruritus

0 Actively Recruiting

Inflammatory Reaction of the ear

0 Actively Recruiting

Blepharitis allergic

0 Actively Recruiting

Neurodermatitis

0 Actively Recruiting

Psoriasis Vulgaris

25 Actively Recruiting

Early Phase 1, Phase 3, Not Applicable, Phase 2, Phase 4, Phase 1

Betamethasone Sodium Phosphate Reviews: What are patients saying about Betamethasone Sodium Phosphate?

4.3

Patient Review

10/28/2007

Betamethasone Sodium Phosphate for Rash

I was in a lot of pain and discomfort due to my reaction to Amoxycillin, but this drug really helped me. Not only did it ease the rash, but it also caused the swelling and pain in my wrists to disappear. I've been very pleased with the results.

2.3

Patient Review

9/15/2010

Betamethasone Sodium Phosphate for Any Disease Following Trauma Involving Joint Cartilage

Unfortunately, I had a severe allergic reaction to this injection on two separate occasions. Anaphalactic shock is not common, but it happened to me.

image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about betamethasone sodium phosphate

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is betamethasone acetate and sodium phosphate?

"Betamethasone is a corticosteroid that helps to relieve swelling, redness, itching, and allergic reactions by working on the immune system."

Answered by AI

What is betamethasone injection used for?

"BETAMETHASONE is a corticosteroid that helps to reduce swelling, redness, itching, and allergic reactions. It is used to treat asthma, allergies, arthritis, Crohn's disease, and ulcerative colitis. It is also used for other conditions, like blood disorders and diseases of the adrenal glands."

Answered by AI

What is the use of betamethasone sodium phosphate tablets?

"It is used to treat a number of different conditions, such as inflammation (swelling), severe allergies, adrenal problems, arthritis, lung or breathing problems, blood or bone marrow problems, eye or vision problems, lupus, serious skin conditions, kidney problems, ulcerative colitis, and flare-ups of multiple sclerosis."

Answered by AI

What are the side effects of betamethasone sodium phosphate?

"An increased blood sugar level can cause trembling, dizziness, weakness, fatigue, and a fast heartbeat. A low potassium level can cause muscle pain and cramps. Skin changes can include _____. Signs of infection can include _____. Mood and behavior changes can occur. Menstrual changes can include spotting or skipping a period."

Answered by AI