Aripiprazole

Irritability, Schizophrenia, Agitation + 10 more
Treatment
1 FDA approval
20 Active Studies for Aripiprazole

What is Aripiprazole

AripiprazoleThe Generic name of this drug
Treatment SummaryAripiprazole lauroxil is an antipsychotic medication used to treat schizophrenia in adults. It works by blocking certain receptors in the brain that are responsible for symptoms like delusions, hallucinations, thought disorders, and social withdrawal. Aripiprazole lauroxil was approved by the FDA in 2015 under the brand name Aristada and can be administered as an intramuscular injection. In July 2020, a new formulation called Aristada Initio was approved which allows for a faster response time of the drug when combined with a single 30 mg oral dose. Aripiprazole lauroxil is generally effective
Abilifyis the brand name
image of different drug pills on a surface
Aripiprazole Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Abilify
Aripiprazole
2002
454

Approved as Treatment by the FDA

Aripiprazole, also known as Abilify, is approved by the FDA for 1 uses such as Schizophrenia .
Schizophrenia
Used to treat Schizophrenia in combination with Aripiprazole lauroxil

Effectiveness

How Aripiprazole Affects PatientsAripiprazole is a medication used to reduce symptoms of schizophrenia, such as delusions or hallucinations. It works by modifying the activity of certain chemicals in the brain. Taking aripiprazole lauroxil is not known to affect one's sexual function or levels of prolactin, a hormone produced in the body.
How Aripiprazole works in the bodyAripiprazole works by targeting different receptors in the brain. It acts like a partial stimulator (agonist) at dopamine D2 and serotonin 5-HT1A receptors, and an inhibitor (antagonist) at serotonin 5-HT2A receptors. This combination leads to reduced positive symptoms of schizophrenia, like hallucinations and delusions, while also improving negative symptoms, like lack of motivation and impaired thinking. Aripiprazole also blocks alpha-1 adrenergic receptors, leading to orthostatic hypotension, and histamine H1 receptors, which can cause drowsiness. The drug binds to up to 90% of dopamine

When to interrupt dosage

The suggested measure of Aripiprazole is contingent upon the determined circumstances. The quantity of dosage is subject to the technique of delivery, as delineated in the table below.
Condition
Dosage
Administration
Schizophrenia
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Irritability
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Bipolar Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Acute Coryza
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Alzheimer's Disease
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Psychotic Depression
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Schizophrenia
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Agitation
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Autism Spectrum Disorder (ASD)
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Tourette Syndrome
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Bipolar Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Bipolar Disorder
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular
Depression
, 5.0 mg, 10.0 mg, 20.0 mg, 30.0 mg, 15.0 mg, 2.0 mg, 300.0 mg, 400.0 mg, 1.0 mg/mL, 9.75 mg/mL, 400.0 mg/mL, 300.0 mg/mL, 7.5 mg/mL
Tablet - Oral, Tablet, , Oral, Tablet, orally disintegrating - Oral, Tablet, orally disintegrating, Injection, powder, for suspension, extended release; Kit - Intramuscular, Injection, powder, for suspension, extended release; Kit, Intramuscular, Injection, powder, for suspension, extended release, Injection, powder, for suspension, extended release - Intramuscular, Solution, Solution - Oral, Injection, solution - Intramuscular, Injection, solution, Injection, powder, lyophilized, for suspension, extended release - Intramuscular, Injection, powder, lyophilized, for suspension, extended release, Injection, Injection - Intramuscular

Warnings

Aripiprazole Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Aripiprazole may interact with Pulse Frequency
There are 20 known major drug interactions with Aripiprazole.
Common Aripiprazole Drug Interactions
Drug Name
Risk Level
Description
Acepromazine
Major
Aripiprazole may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Acepromazine.
Aclidinium
Major
The risk or severity of adverse effects can be increased when Aripiprazole is combined with Aclidinium.
Alfuzosin
Major
Aripiprazole may increase the hypotensive activities of Alfuzosin.
Amisulpride
Major
Aripiprazole may increase the antipsychotic activities of Amisulpride.
Aripiprazole lauroxil
Major
Aripiprazole may increase the orthostatic hypotensive, hypotensive, and antihypertensive activities of Aripiprazole lauroxil.
Aripiprazole Toxicity & Overdose RiskIn rats, an intramuscular injection of aripiprazole is found to be non-toxic up to 60mg. However, in females, males, and monkeys, the oral LD50 is found to be 705mg/kg, 965mg/kg and greater than 2000mg/kg, respectively. Common side effects of overdosing include vomiting, drowsiness, tremor, and akathisia. In some cases, more serious symptoms such as confusion, seizures, irregular heartbeat, and breathing problems may be seen. Aripiprazole can also cause Neuroleptic Malignant Syndrome (N
image of a doctor in a lab doing drug, clinical research

Aripiprazole Novel Uses: Which Conditions Have a Clinical Trial Featuring Aripiprazole?

170 active clinical trials are examining the utility of Aripiprazole in managing Schizophrenia and other related conditions.
Condition
Clinical Trials
Trial Phases
Schizophrenia
97 Actively Recruiting
Phase 3, Not Applicable, Early Phase 1, Phase 4, Phase 1, Phase 2
Bipolar Disorder
0 Actively Recruiting
Bipolar Disorder
0 Actively Recruiting
Acute Coryza
1 Actively Recruiting
Not Applicable
Alzheimer's Disease
15 Actively Recruiting
Not Applicable, Phase 2, Phase 1
Psychotic Depression
0 Actively Recruiting
Irritability
8 Actively Recruiting
Phase 2, Not Applicable, Early Phase 1, Phase 4
Schizophrenia
31 Actively Recruiting
Early Phase 1, Not Applicable, Phase 4
Agitation
3 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Bipolar Disorder
0 Actively Recruiting
Autism Spectrum Disorder (ASD)
60 Actively Recruiting
Phase 2, Phase 3, Not Applicable, Phase 1, Phase 4, Early Phase 1
Depression
213 Actively Recruiting
Phase 3, Phase 2, Not Applicable, Phase 4, Phase 1, Early Phase 1
Tourette Syndrome
3 Actively Recruiting
Not Applicable

Aripiprazole Reviews: What are patients saying about Aripiprazole?

5Patient Review
1/19/2015
Aripiprazole for Additional Medications to Treat Depression
I had been searching for two decades to find a way to combat my depression. I'd tried various types of antidepressants with little-to-no success before finally finding relief in a combination of bupropion, escitalopram, and other mood medications. Once we added Abilify to the mix, it was like a weight had been lifted off my shoulders. I'm able to function now where I wasn't before, and I couldn't be happier with the results.
5Patient Review
3/9/2015
Aripiprazole for Additional Medications to Treat Depression
Lexapro and lithium were good, but adding abilify really helped fine-tune my medication regimen.
5Patient Review
3/8/2021
Aripiprazole for Additional Medications to Treat Depression
This medication has been a game-changer for me in terms of my depression. I feel so much more clearheaded and energetic without feeling manic.
4.7Patient Review
2/14/2013
Aripiprazole for Bipolar Disorder in Remission
4Patient Review
8/15/2022
Aripiprazole for Additional Medications to Treat Depression
I was really hoping this would help me with the anxiety attacks I've been having. So far, it's made them more bearable and given me back some energy. fingers crossed it keeps working!
3.3Patient Review
9/28/2021
Aripiprazole for Schizophrenia
I've been taking this medication for over 10 years now. When I first started, it was great! It helped with my anxiety and nightmares. But then, after a while, I started to experience some negative side effects like gambling and increased sexual desire. And now I find that I'm sleeping more than 16 hours a day and have zero motivation.
3.3Patient Review
10/24/2017
Aripiprazole for Bipolar Disorder in Remission
Overall this medication does what it's supposed to, but I've gained a lot of weight since starting it which is really frustrating.
3Patient Review
4/16/2021
Aripiprazole for Additional Medications to Treat Depression
I've only just started this treatment in place of Prozac, which I was taking for years. I'm also continuing to take cymbalta. I'm feeling a bit nervous about the change, so reviews are helpful. I hope that this will work for my depression and suicidal thoughts.
2.3Patient Review
10/16/2015
Aripiprazole for Bipolar I Disorder with Most Recent Episode Mixed
Unfortunately, this medication caused me to have manic episodes which resulted in uncontrolled spending. I was also only sleeping 3-4 hours a night, which made the effects even worse.
2.3Patient Review
7/31/2017
Aripiprazole for Additional Medications to Treat Depression
I experienced tremors and extreme dizziness after taking just 5mg of this medication. I absolutely need to find a replacement soon.
2Patient Review
10/5/2015
Aripiprazole for Additional Medications to Treat Depression
I tried to quit taking Abilify and it gave me Tardive Dyskinesia. It's really painful, my jaw is constantly aching and my mouth is moving involuntarily from side to side. I want to get off of the drug because I've gained 50 pounds, but it's proving difficult.
2Patient Review
7/23/2021
Aripiprazole for Additional Medications to Treat Depression
I experienced unexpected drowsiness after taking this medication for a few weeks. One day, I was driving and became so exhausted that I could barely keep my eyes open. As a result, I got into a car accident. Because of this incident (and others like it), I no longer take this medication.
1.7Patient Review
6/20/2014
Aripiprazole for Additional Medications to Treat Depression
This medication was a huge disappointment and actually made things worse. I wouldn't wish it on my worst enemy.
1Patient Review
3/7/2021
Aripiprazole for Additional Medications to Treat Depression
I've used this for years without any improvement. It's not a good product.
1Patient Review
3/7/2021
Aripiprazole for Schizophrenia
I've used this for years without any good results.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about aripiprazole

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does aripiprazole make you high?

"Dopamine agonists drugs such as aripiprazole work by activating dopamine receptors in the brain, which has the effect of opening up those pathways. Some of the potential side effects of this include euphoria, increased orgasmic activity, and developing addictions to activities such as gambling, shopping, binge eating, and sex."

Answered by AI

What is aripiprazole is used for?

"Aripiprazole is a medication used to treat mental conditions such as bipolar disorder, depression, and schizophrenia. It can also be used in children to treat irritability associated with autistic disorder and Tourette syndrome."

Answered by AI

What side effects does aripiprazole have?

"You may experience a headache, nervousness, or restlessness. You may also feel dizzy, unsteady, or have trouble keeping your balance. Additionally, you may have heartburn, constipation, diarrhea, or stomach pain."

Answered by AI

Is aripiprazole the same as Xanax?

"The pill form of Aripiprazole is a prescription drug that comes in four oral dosage forms. Alprazolam is a prescription medication that is available as brand name drugs called Alprazolam Intensol, Xanax, or Xanax XR."

Answered by AI

Clinical Trials for Aripiprazole

Image of Cumberland Medical Center in Crossville, United States.

Quest AD-Detect Blood Test for Alzheimer's Disease

60 - 90
All Sexes
Crossville, TN
The goal of this clinical trial is to determine if utilizing the Quest AD-Detect blood test, while patient's are hospitalized for a cognitive diagnosis (such as delirium or encephalopathy), will result in an earlier diagnosis of underlying Alzheimer's disease. * Will this blood test have the ability to distinguish between Alzheimer's disease and other causes of cognitive impairment in the inpatient setting? * Neurology Clinic will complete a 6-month post-hospitalization follow up with patients who have had the Quest AD-Detect Alzheimer's Disease blood test completed while they were inpatient to discuss the risk assessment portfolio
Recruiting
Has No Placebo
Cumberland Medical Center (+5 Sites)Samuel Moore, MD
Have you considered Aripiprazole clinical trials? We made a collection of clinical trials featuring Aripiprazole, we think they might fit your search criteria.Go to Trials
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Peer-Delivered Behavioral Activation for Depression

18+
All Sexes
Detroit, MI
Low-income individuals have limited access to evidence-based interventions for mental health. Peer recovery specialists, individuals in recovery from mental health and/or substance use problems, have the potential to increase access to evidence-based interventions for individuals from low-resource communities, particularly when trained and supervised in models that are acceptable and feasible in these communities. This study will examine the effectiveness and implementation potential of a peer-delivered evidence-based intervention (Behavioral Activation) among individuals receiving services from a community-based treatment setting providing integrated physical and behavioral healthcare.
Waitlist Available
Has No Placebo
Detroit Recovery Project
Image of Wellstar MCG Hospital, Neurology Memory Clinic in Augusta, United States.

Deep Brain Stimulation for Alzheimer's Disease

65 - 85
All Sexes
Augusta, GA
The purpose of this study is to test a new procedure to treat Alzheimer's disease. The procedure is called intermittent Deep Brain Stimulation (DBS) of the nucleus basalis of Meynert. There will be up to six participants enrolled at Wellstar MCG Memory Clinic. There will be another six participants similarly enrolled to act as a control group that does not receive DBS. This second group will document the course of progression of Alzheimer's disease under the normal standard of care. The main goal of the study is to determine if DBS can sustain or improve cognition in Alzheimer's disease for at least two years. Participant data, with identifying information removed, may be shared with online repositories for comparison with trials with similar subjects.
Phase 1
Waitlist Available
Wellstar MCG Hospital, Neurology Memory Clinic
Image of The University of Iowa in Iowa City, United States.

fMRI for Cognitive Flexibility

18 - 35
All Sexes
Iowa City, IA
The goal of this basic experimental research study is to examine how the human thalamus supports flexible thinking and behavior. Specifically, the research aims to elucidate how the mediodorsal (MD) thalamus encodes and updates "context"-the mental framework that determines which rules or actions are relevant in a given situation. This work may contribute to understanding why certain psychiatric conditions, such as schizophrenia and ADHD, involve difficulties with cognitive flexibility and control. The primary research questions are: Does the MD thalamus represent the context that organizes how working memory guides task selection? Does the MD thalamus signal when context needs to be updated after a change in task demands? Do these thalamic representations support generalization to new situations or rules? Participants will complete cognitive tasks while undergoing high-resolution brain imaging using 7-Tesla MRI. The investigators will combine behavioral data, computational modeling, and advanced neuroimaging analyses to examine how the thalamus interacts with the cortex during flexible decision-making.
Waitlist Available
Has No Placebo
The University of Iowa
Have you considered Aripiprazole clinical trials? We made a collection of clinical trials featuring Aripiprazole, we think they might fit your search criteria.Go to Trials
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Transcranial Direct Current Stimulation for Depression

18 - 85
All Sexes
San Diego, CA
The investigators propose a single-arm, open-label study to evaluate the effectiveness, safety, tolerability and feasibility of at-home transcranial direct current stimulation (tDCS) as a treatment for depression, particularly in cases where patients have not responded well to traditional therapies. Treatment will be delivered over a 2-week period with daily weekday treatments i.e., five tDCS sessions, each lasting 20 minutes, spaced by approximately 20-minute inter-session intervals, for a total of three hours a day. Participants will self-administer treatment at home under direct remote supervision. Pre- and post- treatment neurophysiological biomarkers sessions will also be carried out. The study aims to examine changes in mood, brain activity, and related clinical outcomes before, during, and after treatment, with the goal to provide more information that can be used for future studies.
Recruiting
Has No Placebo
UCSD Interventional Psychiatry
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Multimodal Intervention for Bipolar Disorder

18 - 35
All Sexes
Hamilton, Canada
People with bipolar disorder (BD) are at high risk of relapse following hospital discharge, partly due to a lack of BD-specific expertise and resources within community services required for comprehensive treatment. Although clinical guidelines recommend combining medication and psychosocial support, and research shows that early intervention is associated with improved outcomes, no structured care programs currently exist for individuals in the early stages of BD, contributing to chronic illness progression and preventable hospitalizations. This open-label pilot trial will assess the feasibility, acceptability, and preliminary effectiveness of a structured care pathway to support the transition from hospital to community care. The intervention includes group-based psychoeducation, individual peer support, and personalized support for community healthcare providers to improve illness insight, treatment adherence, and symptom management.
Waitlist Available
Has No Placebo
St. Joseph's Healthcare Hamilton
Have you considered Aripiprazole clinical trials? We made a collection of clinical trials featuring Aripiprazole, we think they might fit your search criteria.Go to Trials
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