Vivlodex

Arthritis, Juvenile, Arthritis, Juvenile, Postoperative Pain + 9 more
Treatment
20 Active Studies for Vivlodex

What is Vivlodex

MeloxicamThe Generic name of this drug
Treatment SummaryMeloxicam is a type of pain reliever called a nonsteroidal anti-inflammatory drug (NSAID). It is used to treat various types of pain including pain related to musculoskeletal conditions, arthritis, and rheumatoid arthritis. It has a longer lasting effect than most other NSAIDs, which means it only needs to be taken once a day. It comes in three forms: oral, transdermal, and intravenous. Meloxicam is a special type of NSAID known as a COX-2 inhibitor which may help reduce the risk of stomach upset, although this is still a subject of debate.
Mobicis the brand name
image of different drug pills on a surface
Vivlodex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mobic
Meloxicam
2000
284

Effectiveness

How Vivlodex Affects PatientsMeloxicam is a painkiller with fever-reducing effects, and has been shown to reduce inflammation in those with rheumatoid arthritis. Similar to other NSAIDs, taking meloxicam long-term can lead to issues with the kidneys or the cardiovascular system. While meloxicam is believed to have less gastrointestinal side effects than other NSAIDs, it can still lead to inflammation, bleeding, and ulcers. One study found that 13% of patients taking meloxicam suffered these side effects compared to 19% of those taking the NSAID diclofenac. However, the side effects in patients taking meloxic
How Vivlodex works in the bodyMeloxicam reduces inflammation and pain by targeting enzymes that create prostaglandins. Prostaglandins are molecules that irritate nerve endings and make you feel pain. Meloxicam is more effective at targeting one type of enzyme than the other, which helps it reduce pain and inflammation without irritating the stomach.

When to interrupt dosage

The suggested dosage of Vivlodex is contingent upon the diagnosed condition, such as Therapeutic procedure, Osteoarthritis (OA) and Dental Pain. The amount of dosage fluctuates with the administration mode (e.g. Suspension or Kit) outlined in the table below.
Condition
Dosage
Administration
Postoperative Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Rheumatoid Arthritis
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Dental Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Ankle
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Osteoarthritis
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Therapeutic procedure
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Open Abdominal Surgery
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Peptic Ulcer
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Arthritis, Juvenile
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Arthritis, Juvenile
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration
Neuropathic Pain
, 7.5 mg/mL, 7.5 mg, 15.0 mg, 5.0 mg, 10.0 mg, 30.0 mg/mL, 6.0 mg, 12.0 mg, 1.8 mg, 1.8 mg/mL, 0.9 mg/mL, 1.2 mg/mL, 6.0 mg/mL
, Suspension, Oral, Suspension - Oral, Tablet, Tablet - Oral, Capsule, Capsule - Oral, Kit, Tablet, orally disintegrating, Tablet, orally disintegrating - Oral, Injection - Intravenous, Injection, Intravenous, Kit - Oral, Solution, Intralesional, Solution - Intralesional, Oral; Topical, Kit - Oral; Topical, Infiltration, Solution - Infiltration

Warnings

Vivlodex has four contraindications and should not be utilized in combination with the circumstances specified in the below table.Vivlodex Contraindications
Condition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Pulse Frequency
Coronary Artery Bypass Surgery
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Pulse Frequency
There are 20 known major drug interactions with Vivlodex.
Common Vivlodex Drug Interactions
Drug Name
Risk Level
Description
Acetylsalicylic acid
Major
The risk or severity of gastrointestinal bleeding can be increased when Meloxicam is combined with Acetylsalicylic acid.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Meloxicam.
Mifamurtide
Major
The therapeutic efficacy of Mifamurtide can be decreased when used in combination with Meloxicam.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Meloxicam is combined with Neomycin.
Omacetaxine mepesuccinate
Major
The risk or severity of bleeding can be increased when Meloxicam is combined with Omacetaxine mepesuccinate.
Vivlodex Toxicity & Overdose RiskThe lowest toxic dose of meloxicam in rats has been found to be 98 mg/kg. An overdose of this drug may lead to shallow breathing, seizures, reduced urination, stomach or intestinal irritation, nausea, vomiting, or bleeding from the digestive tract. To help eliminate the drug, supportive treatment and cholestyramine may be used.
image of a doctor in a lab doing drug, clinical research

Vivlodex Novel Uses: Which Conditions Have a Clinical Trial Featuring Vivlodex?

118 active clinical trials are currently being conducted to assess the potential of Vivlodex in alleviating Ankle Pain, Open Abdominal Surgery and Pain.
Condition
Clinical Trials
Trial Phases
Peptic Ulcer
0 Actively Recruiting
Open Abdominal Surgery
1 Actively Recruiting
Not Applicable
Neuropathic Pain
4 Actively Recruiting
Not Applicable, Phase 1, Phase 2
Dental Pain
1 Actively Recruiting
Not Applicable
Postoperative Pain
19 Actively Recruiting
Phase 4, Phase 2, Phase 1, Phase 3, Not Applicable
Arthritis, Juvenile
0 Actively Recruiting
Osteoarthritis
0 Actively Recruiting
Ankle
0 Actively Recruiting
Pain
0 Actively Recruiting
Rheumatoid Arthritis
54 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Arthritis, Juvenile
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting

Vivlodex Reviews: What are patients saying about Vivlodex?

5Patient Review
7/21/2016
Vivlodex for Joint Damage causing Pain and Loss of Function
I haven't felt this good in over a decade! Not only is the pain gone, but my mobility has increased. I was worried about the stomach upset side effect, but taking it with food and water helps a lot. And the hard candy or peppermint is a nice touch.
5Patient Review
7/30/2016
Vivlodex for Joint Damage causing Pain and Loss of Function
I found this medication to be really effective in reducing pain and stiffness. I also didn't have any problems with it upsetting my stomach, which is a big plus.
4.7Patient Review
4/26/2017
Vivlodex for Joint Damage causing Pain and Loss of Function
Though it takes a little while to work, this medication is much more effective than other pain relievers I've tried. Now that I've been taking it regularly, my joint pain has decreased significantly and I only need to take it a couple times a week.
4Patient Review
8/8/2016
Vivlodex for Rheumatoid Arthritis
I've been taking this drug for almost a week and it's helped me a lot.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about vivlodex

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Vivlodex the same as meloxicam?

"VIVLODEX is available as pink and blue capsules containing 5 mg or 10 mg for oral administration. It is a nonsteroidal anti-inflammatory drug."

Answered by AI

What is Vivlodex used for?

"Meloxicam acts as a pain reliever, reducing swelling and stiffness in joints. It is classified as a nonsteroidal anti-inflammatory drug (NSAID). If you suffer from a chronic condition such as arthritis, be sure to speak to your doctor about non-drug treatments and other options for managing your pain."

Answered by AI

What are the side effects of Vivlodex?

"The side effects of the medication include diarrhea, nausea, abdominal discomfort, joint pain, urinary tract infection, high blood pressure, diarrhea, and headache."

Answered by AI

Is meloxicam a painkiller?

"Meloxicam is a strong painkiller that must be prescribed by a doctor. It can come in the form of a regular tablet, a disintegrating tablet, a capsule, or an oral suspension liquid. Some popular brand names for meloxicam include Mobic, Vivlodex, Qmiiz ODT, and Comfort Pac-Meloxicam."

Answered by AI

Clinical Trials for Vivlodex

Image of Weill Cornell Medical College in New York, United States.

Health Coaching for Rheumatoid Arthritis

18+
All Sexes
New York, NY
The goal of this clinical trial is to learn if peer coaching works to reduce levels of anxiety and/or depression in adults diagnosed with Rheumatoid Arthritis (RA). The main questions it aims to answer are: Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months from baseline? Do people with RA who complete the intervention with a peer coach have lower levels of anxiety and/or depression at 6 months compared to those in the control arm? Researchers will compare the peer coaching intervention to an active-control arm (where people without RA coach participants on general health and nutrition topics) to see if peer coaching works to reduce anxiety and/or depression. Participants will meet with a coach every week for 9 weeks and complete several surveys before, during and after the intervention
Recruiting
Has No Placebo
Weill Cornell Medical CollegeIris Y Navarro-Millán, MDBristol-Myers Squibb
Image of Humana Healthcare Research, Inc. in Louisville, United States.

Academic Detailing for Rheumatoid Arthritis

Any Age
All Sexes
Louisville, KY
The goal of this trial is to learn if an interactive evidence-based educational outreach visits to clinicians who prescribe biologics change prescribing of biosimilar medications. The main questions it aims to answer are: 1. Do educational outreach visits lead to a higher number of prescriptions for biosimilar versions of adalimumab? 2. Do in-person or virtual visits work better? Researchers will compare clinicians offered the educational outreach visit to those who are not offered the visit to see if there is a difference in prescribing of biosimilar versions of adalimumab instead of the original brand-name version. Participants will be offered the chance to meet with a trained clinician who will provide educational information tailored to their knowledge and attitudes on the topic. They will also be provided an educational brochure and patient educational materials.
Waitlist Available
Has No Placebo
Humana Healthcare Research, Inc. (+1 Sites)
Have you considered Vivlodex clinical trials? We made a collection of clinical trials featuring Vivlodex, we think they might fit your search criteria.Go to Trials
Image of UI Health Care Center for Advanced Reproductive Care in Iowa City, United States.

Ketorolac for Infertility Treatment

18 - 37
Female
Iowa City, IA
Ketorolac is a medication often used to relieve pain after surgery. In the past, infertility doctors have been cautious about using ketorolac after egg retrieval for patients planning a fresh embryo transfer (usually done 5 days later). The concern was that ketorolac might increase the risk of bleeding or reduce the chances of the embryo implanting in the uterus. This concern comes from how ketorolac works-it blocks certain chemicals in the body (like prostaglandins and thromboxane) that help with blood clotting and play a role in early pregnancy. However, a large review of past studies found no real evidence that ketorolac increases bleeding risk. In fact, ketorolac is now routinely used for pain relief in IVF cycles where embryos are frozen and not transferred right away. More recent studies from Boston and Chapel Hill have shown that ketorolac provides better pain control and does not appear to harm IVF outcomes, even when embryos are transferred fresh (within the same cycle). Despite these encouraging findings, many IVF clinics still avoid using ketorolac during fresh cycles because of the theoretical concerns. That's why we need stronger, higher-quality research. This study aims to fill that gap by conducting a double-blind randomized controlled trial to find out whether giving ketorolac through an IV after egg retrieval affects important IVF outcomes-especially the chance of implantation and live birth-in patients undergoing fresh embryo transfers. Patients who choose to join the study will randomly be placed into one of two groups. One group will get ketorolac (a pain medicine) after an IVF egg retrieval. The other group will not get ketorolac after egg retrieval. Everything else in their IVF care will stay the same as it normally would. Primary outcome will be implantation rate following fresh embryo transfers in patients receiving ketorolac (30mg IV) vs no ketorolac for post-retrieval analgesia. Secondary outcomes will include pain scale, narcotics required, time to discharge, need for evaluation w/in 24 hours for pain/bleeding, clinical pregnancy rates, miscarriage rates, and live birth rates following fresh embryo transfers in patients receiving ketorolac vs no ketorolac for post-retrieval analgesia.
Phase 4
Recruiting
UI Health Care Center for Advanced Reproductive Care
Image of University of Minnesota Medical School, Division of Rheumatic and Autoimmune Diseases in Minneapolis, United States.

Ultrasound Therapy for Rheumatoid Arthritis

18+
All Sexes
Minneapolis, MN
The At-Home ULTRA Study will evaluate performance of the MINI system as indicated for the treatment of adults with active, moderate to severe rheumatoid arthritis who are inadequate responders or are intolerant to conventional synthetic disease-modifying anti-rheumatic drugs (csDMARDs), biologic DMARDs (bDMARDs), or targeted synthetic DMARDs (tsDMARDs). The non-invasive study device delivers ultrasound stimulation to the spleen to reduce inflammation. The study will enroll at least 60 participants at up to 8 sites. There will be three arms consisting of two active stimulation groups (treatment) and one non-active stimulation group (sham-control). After completing the double-blinded primary endpoint assessment period at Week 12, there will be a one-way crossover of control participants to active stimulation and an additional 12 week follow-up with all participants to evaluate long-term outcomes.
Recruiting
Drug
University of Minnesota Medical School, Division of Rheumatic and Autoimmune DiseasesHubert LimSecondWave Systems Inc.
Have you considered Vivlodex clinical trials? We made a collection of clinical trials featuring Vivlodex, we think they might fit your search criteria.Go to Trials
Image of Rutgers School of Dental Medicine in Newark, United States.

Temporo-masseteric Nerve Block for Postoperative Pain

18+
All Sexes
Newark, NJ
The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric Nerve Block (TMNB) injection to decrease jaw muscle pain, overall pain, improve mouth opening and minimize pain medication consumption. 80 participants undergoing lower third molar removal under sedation will be enrolled. Those who develop significant jaw muscle pain on the following day will be randomized to receive either the TMNB injection or a placebo. Daily ecological momentary assessments (EMAs) will be collected reflecting elements of patient experience for all participants. On Day 8, participants return for an end-of-study evaluation and return their unused pain medications. Up to 40 participants who are randomized to receive TMNB/placebo will be recruited to participate in a qualitative interview regarding their experience.
Phase 2
Waitlist Available
Rutgers School of Dental Medicine
Image of St. Lawrence Health in Potsdam, United States.

Primary Care for Rheumatoid Arthritis

18+
All Sexes
Potsdam, NY
Rheumatoid arthritis (RA) is a complex autoimmune disease where the immune system attacks healthy joint tissue; causing pain, swelling, and stiffness of the joints. This disease effects lots of people in the US and can lead to major joint damage if not properly treated. In rural areas like northern NY, these are underserved areas for RA patients, thus many patients struggle to get the appropriate care. This model is testing whether primary care providers (PCP) can safely and effectively provide stable RA patients with the proper treatment rather than send them to a specialist. PCPs were trained through classes, case reviews, and a final exam. Patients will be randomly assigned to either see a trained PCP or their normal rheumatologist at the rheumatology clinic. This study will examine how patients are doing over a year using medical exams and patient feedback. If this model proves to be successful, it will make RA treatment easier and more affordable for patients.
Recruiting
Has No Placebo
St. Lawrence HealthEyal Kedar, MD
Have you considered Vivlodex clinical trials? We made a collection of clinical trials featuring Vivlodex, we think they might fit your search criteria.Go to Trials
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