What is Vivlodex
MeloxicamThe Generic name of this drug
Treatment SummaryMeloxicam is a type of pain reliever called a nonsteroidal anti-inflammatory drug (NSAID). It is used to treat various types of pain including pain related to musculoskeletal conditions, arthritis, and rheumatoid arthritis. It has a longer lasting effect than most other NSAIDs, which means it only needs to be taken once a day. It comes in three forms: oral, transdermal, and intravenous. Meloxicam is a special type of NSAID known as a COX-2 inhibitor which may help reduce the risk of stomach upset, although this is still a subject of debate.
Mobicis the brand name
Vivlodex Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Mobic
Meloxicam
2000
284
Effectiveness
How Vivlodex Affects PatientsMeloxicam is a painkiller with fever-reducing effects, and has been shown to reduce inflammation in those with rheumatoid arthritis. Similar to other NSAIDs, taking meloxicam long-term can lead to issues with the kidneys or the cardiovascular system. While meloxicam is believed to have less gastrointestinal side effects than other NSAIDs, it can still lead to inflammation, bleeding, and ulcers. One study found that 13% of patients taking meloxicam suffered these side effects compared to 19% of those taking the NSAID diclofenac. However, the side effects in patients taking meloxic
How Vivlodex works in the bodyMeloxicam reduces inflammation and pain by targeting enzymes that create prostaglandins. Prostaglandins are molecules that irritate nerve endings and make you feel pain. Meloxicam is more effective at targeting one type of enzyme than the other, which helps it reduce pain and inflammation without irritating the stomach.
When to interrupt dosage
The suggested dosage of Vivlodex is contingent upon the diagnosed condition, such as Therapeutic procedure, Osteoarthritis (OA) and Dental Pain. The amount of dosage fluctuates with the administration mode (e.g. Suspension or Kit) outlined in the table below.Condition
Dosage
Administration
Polyarticular juvenile rheumatoid arthritis, chronic or unspecified
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Dental Pain
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Postoperative Pain
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Pain
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Neuropathic Pain
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Rheumatoid Arthritis
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Osteoarthritis (OA)
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Ankle
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Peptic Ulcer
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Pauciarticular juvenile rheumatoid arthritis
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Therapeutic procedure
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Open Abdominal Surgery
7.5 mg/mL, , 7.5 mg, 15.0 mg, 1.8 mg, 6.0 mg, 0.9 mg/mL, 6.0 mg/mL, 1.8 mg/mL, 12.0 mg, 5.0 mg, 10.0 mg, 1.2 mg/mL, 30.0 mg/mL
Suspension, Kit, Solution, Suspension - Oral, Oral; Topical, Tablet - Oral, Kit - Oral; Topical, Solution, gel forming, extended release - Infiltration, Tablet, orally disintegrating, Oral, , Infiltration, Injection - Intravenous, Tablet, orally disintegrating - Oral, Capsule - Oral, Solution, gel forming, extended release, Injection, Intravenous, Tablet, Intralesional, Kit - Oral, Capsule, Solution - Intralesional, Solution - Infiltration
Warnings
Vivlodex has four contraindications and should not be utilized in combination with the circumstances specified in the below table.Vivlodex ContraindicationsCondition
Risk Level
Notes
Coronary Artery Bypass Surgery
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Toxoplasma Infections
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Toxoplasma Infections
Severe Hypersensitivity Reactions
Do Not Combine
Meloxicam may interact with Toxoplasma Infections
Common Vivlodex Drug Interactions
Drug Name
Risk Level
Description
Acetylsalicylic acid
Major
The risk or severity of gastrointestinal bleeding can be increased when Meloxicam is combined with Acetylsalicylic acid.
Macimorelin
Major
The therapeutic efficacy of Macimorelin can be decreased when used in combination with Meloxicam.
Mifamurtide
Major
The therapeutic efficacy of Mifamurtide can be decreased when used in combination with Meloxicam.
Neomycin
Major
The risk or severity of nephrotoxicity can be increased when Meloxicam is combined with Neomycin.
Omacetaxine mepesuccinate
Major
The risk or severity of bleeding can be increased when Meloxicam is combined with Omacetaxine mepesuccinate.
Vivlodex Toxicity & Overdose RiskThe lowest toxic dose of meloxicam in rats has been found to be 98 mg/kg. An overdose of this drug may lead to shallow breathing, seizures, reduced urination, stomach or intestinal irritation, nausea, vomiting, or bleeding from the digestive tract. To help eliminate the drug, supportive treatment and cholestyramine may be used.
Vivlodex Novel Uses: Which Conditions Have a Clinical Trial Featuring Vivlodex?
118 active clinical trials are currently being conducted to assess the potential of Vivlodex in alleviating Ankle Pain, Open Abdominal Surgery and Pain.Condition
Clinical Trials
Trial Phases
Rheumatoid Arthritis
62 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Pauciarticular juvenile rheumatoid arthritis
0 Actively Recruiting
Osteoarthritis (OA)
0 Actively Recruiting
Therapeutic procedure
0 Actively Recruiting
Neuropathic Pain
31 Actively Recruiting
Phase 1, Phase 2, Not Applicable, Phase 3
Polyarticular juvenile rheumatoid arthritis, chronic or unspecified
0 Actively Recruiting
Ankle
0 Actively Recruiting
Peptic Ulcer
0 Actively Recruiting
Postoperative Pain
15 Actively Recruiting
Phase 4, Not Applicable, Phase 3, Early Phase 1
Open Abdominal Surgery
0 Actively Recruiting
Pain
1 Actively Recruiting
Phase 1
Dental Pain
0 Actively Recruiting
Vivlodex Reviews: What are patients saying about Vivlodex?
5Patient Review
7/21/2016 I haven't felt this good in over a decade! Not only is the pain gone, but my mobility has increased. I was worried about the stomach upset side effect, but taking it with food and water helps a lot. And the hard candy or peppermint is a nice touch.
5Patient Review
7/30/2016 I found this medication to be really effective in reducing pain and stiffness. I also didn't have any problems with it upsetting my stomach, which is a big plus.
4.7Patient Review
4/26/2017 Though it takes a little while to work, this medication is much more effective than other pain relievers I've tried. Now that I've been taking it regularly, my joint pain has decreased significantly and I only need to take it a couple times a week.
4Patient Review
8/8/2016 I've been taking this drug for almost a week and it's helped me a lot.
Patient Q&A Section about vivlodex
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Vivlodex the same as meloxicam?
"VIVLODEX is available as pink and blue capsules containing 5 mg or 10 mg for oral administration. It is a nonsteroidal anti-inflammatory drug."
Answered by AI
What is Vivlodex used for?
"Meloxicam acts as a pain reliever, reducing swelling and stiffness in joints. It is classified as a nonsteroidal anti-inflammatory drug (NSAID). If you suffer from a chronic condition such as arthritis, be sure to speak to your doctor about non-drug treatments and other options for managing your pain."
Answered by AI
What are the side effects of Vivlodex?
"The side effects of the medication include diarrhea, nausea, abdominal discomfort, joint pain, urinary tract infection, high blood pressure, diarrhea, and headache."
Answered by AI
Is meloxicam a painkiller?
"Meloxicam is a strong painkiller that must be prescribed by a doctor. It can come in the form of a regular tablet, a disintegrating tablet, a capsule, or an oral suspension liquid. Some popular brand names for meloxicam include Mobic, Vivlodex, Qmiiz ODT, and Comfort Pac-Meloxicam."
Answered by AI