Vivactil

Depression
Treatment
1 FDA approval
20 Active Studies for Vivactil

What is Vivactil

ProtriptylineThe Generic name of this drug
Treatment SummaryProtriptyline hydrochloride is an antidepressant medication used to treat depression. It belongs to the tricyclic antidepressant (TCA) class of drugs which increase serotonin and norepinephrine levels in the brain to help alleviate symptoms of depression. It can also cause sedation in non-depressed individuals and has side effects such as blurred vision, dry mouth, constipation, and urinary retention.
Vivactilis the brand name
image of different drug pills on a surface
Vivactil Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Vivactil
Protriptyline
2000
15

Approved as Treatment by the FDA

Protriptyline, commonly known as Vivactil, is approved by the FDA for 1 uses including Depression .
Depression
Helps manage Depression

Effectiveness

How Vivactil Affects PatientsProtriptyline is a type of antidepressant that works by increasing the levels of norepinephrine and serotonin in the brain. It usually takes two weeks to start seeing results. This drug may also make it easier to regulate emotions, reduce pain, and prevent migraines. The specific way it works to reduce pain is not known, but it is believed that it affects the body’s natural opioid system.
How Vivactil works in the bodyProtriptyline helps the body keep more of the naturally occurring chemicals norepinephrine and serotonin in the brain, which can help relieve symptoms of depression.

When to interrupt dosage

The advised dosage of Vivactil is contingent upon the determined condition. The amount also fluctuates as per the approach of delivery listed in the table below.
Condition
Dosage
Administration
Depression
5.0 mg, , 10.0 mg
, Tablet, film coated, Oral, Tablet, film coated - Oral, Tablet, Tablet - Oral

Warnings

Vivactil Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Myocardial Infarction
Do Not Combine
Pulse Frequency
Do Not Combine
There are 20 known major drug interactions with Vivactil.
Common Vivactil Drug Interactions
Drug Name
Risk Level
Description
4-Methoxyamphetamine
Major
Protriptyline may increase the vasopressor activities of 4-Methoxyamphetamine.
Azelastine
Major
Protriptyline may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Bromocriptine
Major
Protriptyline may increase the vasopressor activities of Bromocriptine.
Cirazoline
Major
Protriptyline may increase the vasopressor activities of Cirazoline.
Desvenlafaxine
Major
The risk or severity of adverse effects can be increased when Protriptyline is combined with Desvenlafaxine.
Vivactil Toxicity & Overdose RiskPossible side effects of taking the drug include anxiety, blood disorders, confusion, decreased sex drive, dizziness, flushing, headache, impotence, insomnia, low blood pressure, nightmares, irregular heartbeat, rash, seizures, sensitivity to sunlight, digestive issues, drowsiness, low blood pressure when standing, blurred vision, dry mouth, constipation, difficulty urinating, worsened memory and delirium, and worsening of bipolar depression. Withdrawal symptoms can include digestive problems, anxiety, and difficulty sleeping.
image of a doctor in a lab doing drug, clinical research

Vivactil Novel Uses: Which Conditions Have a Clinical Trial Featuring Vivactil?

602 active trials are presently being conducted to assess the efficacy of Vivactil in alleviating symptoms of Depression.
Condition
Clinical Trials
Trial Phases
Depression
698 Actively Recruiting
Phase 2, Not Applicable, Phase 3, Phase 1, Early Phase 1, Phase 4

Vivactil Reviews: What are patients saying about Vivactil?

5Patient Review
1/20/2009
Vivactil for Generalized Attack of Muscular Weakness
I was originally prescribed this medication for headaches when I was 16. Unfortunately, it caused me to become more depressed so they added another antidepressant. I took the combination of drugs for three years but my condition continued to worsen. In my opinion, antidepressants should be closely monitored by parents of teenagers.
4Patient Review
3/24/2011
Vivactil for Generalized Attack of Muscular Weakness
I was prescribed this as an abortive for migraines. I have been on this and several other medications for 4 months. I do not think this medication is working for me at all. I am supposed to take up to 3 15mg as needed but it never takes the migraine away.
3Patient Review
11/5/2007
Vivactil for Depression
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about vivactil

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What class of drug is protriptyline?

"Protriptyline is a tricyclic antidepressant that works by increasing the amounts of certain natural substances in the brain that help maintain mental balance."

Answered by AI

What is Vivactil used for?

"This medication is used to treat mental and mood problems. Some of the benefits include improved mood, feelings of well-being, and increased energy levels. It is classified as a tricyclic antidepressant."

Answered by AI

Does protriptyline have side effects?

"The following side effects may occur: drowsiness, dizziness, dry mouth, blurred vision, constipation, weight gain, or trouble urinating. If you experience any of these side effects, tell your doctor or pharmacist. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position."

Answered by AI

What is the generic name for Vivactil?

"Vivactil is an antidepressant that is used to treat symptoms of depression. Vivactil is a tricyclic antidepressant, which is a type of antidepressant that is used to treat symptoms of depression."

Answered by AI

Clinical Trials for Vivactil

Have you considered Vivactil clinical trials? We made a collection of clinical trials featuring Vivactil, we think they might fit your search criteria.
Have you considered Vivactil clinical trials? We made a collection of clinical trials featuring Vivactil, we think they might fit your search criteria.
Have you considered Vivactil clinical trials? We made a collection of clinical trials featuring Vivactil, we think they might fit your search criteria.