Behavioral Economics Strategies for Antibiotic Duration in Skin Infections

(SSTIBE Trial)

Recruiting in Columbus (<10 mi)

Overseen By Joshua Watson, MD

Age: Any Age

Sex: Any

Trial Phase: Academic

Sponsor: Nationwide Children's Hospital

Must be taking: Antibiotics

Disqualifiers: Immunocompromising conditions, burns, others

No Placebo Group All trial participants will receive the active study treatment (no placebo)

Compensation: Varies

Number of Visits: Unknown

Duration: 12 months

1634 Participants Needed

Trial Summary

What is the purpose of this trial?

This trial tests if a special computer feature can help doctors prescribe the right amount of antibiotics for skin infections by making it easier to follow guidelines and requiring explanations for longer prescriptions.

Research Team

Kali Broussard, MD

Principal Investigator

Nationwide Children's Hospital

Joshua Watson, MD

Principal Investigator

Nationwide Children's Hospital

Eligibility Criteria

This trial is for patients at Nationwide Children's Hospital primary care clinics with certain skin and soft tissue infections (like cellulitis, abscesses, or impetigo) who have been prescribed oral antibiotics. It excludes very young infants, those with specific conditions like hidradenitis suppurativa, bites from animals or humans, foreign body-related infections, burns, or weakened immune systems.

Inclusion Criteria

Patients who receive care at Nationwide Children's Hospital primary care clinics.

I have been diagnosed with a skin infection and prescribed antibiotics.

Exclusion Criteria

I have a condition that weakens my immune system.

I have burns.

I have been diagnosed with hidradenitis suppurativa.

Timeline

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Implementation of behavioral economics strategies in antibiotic prescription for skin and soft tissue infections

12 months

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Treatment Details

Interventions

• Default Duration order Panel

Trial Overview The study tests if using behavioral economics strategies can change how doctors prescribe antibiotics for skin and soft tissue infections compared to just educating them. The focus is on reducing the duration of antibiotic use without compromising treatment effectiveness.

Participant Groups

Group I: Intervention Experimental Treatment 1 Intervention

Intervention clinics receiving fully functional Epic order panel with set default \[short\] duration by diagnosis: for cellulitis and drained abscess, 5 days. For impetigo and undrained abscess, 7 days.

Group II: Control Active Control 1 Intervention

Control clinics receiving basic Epic order panel with antibiotic doses by diagnosis but duration free text (must be entered manually by clinician prescriber).

Who Is Running the Clinical Trial?

Nationwide Children's Hospital

Lead Sponsor

Trials

354

Recruited

5,228,000+