Valtoco

Athetosis, Lockjaw, Syndrome + 11 more
Treatment
20 Active Studies for Valtoco

What is Valtoco

DiazepamThe Generic name of this drug
Treatment SummaryDiazepam is a type of anti-anxiety medication that helps to reduce seizures, anxiety, and insomnia. It works by increasing the activity of a brain chemical called gamma-aminobutyric acid. It has been used for many years to treat a variety of conditions and recently, an auto-injectable form was approved by the FDA. This form is used to quickly and effectively treat uncontrolled seizures and is an important tool for people with epilepsy.
Valiumis the brand name
image of different drug pills on a surface
Valtoco Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Valium
Diazepam
1963
289

Effectiveness

How Valtoco Affects PatientsDiazepam is a type of medicine that helps to reduce anxiety, make people sleepy, relax muscles, and stop seizures. It is believed that these effects come from its ability to help increase the activity of the chemical called GABA in the brain, which helps to slow down the nervous system.
How Valtoco works in the bodyDiazepam is a medication that helps relax muscles, reduce seizures, and make you drowsy. It works by attaching to receptors in the brain and spinal cord. This boosts the effects of a chemical in the body called GABA, which helps with sleep, memory, anxiety, and controlling overactivity in the nervous system.

When to interrupt dosage

The prescribed dosage of Valtoco is contingent upon the diagnosed condition, including Muscle Tissue, Seizures and Anger Management Therapy. The amount of dosage depends upon the method of administration outlined in the table beneath.
Condition
Dosage
Administration
Drug Resistant Epilepsy
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Seizures
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Anger Management Therapy
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Muscle Tissue
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Athetosis
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Lockjaw
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Syndrome
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Motor Neuron Disease, Upper
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Sedation therapy
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Sedation
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Generalized Anxiety Disorder
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Anxiety Disorders
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Stiff-Person Syndrome
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Status Epilepticus
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
Solution, Solution - Oral, , Oral, Rectal, Gel, Gel - Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution, Injection, solution - Intramuscular; Intravenous, Kit, Liquid, Liquid - Intramuscular; Intravenous, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Intramuscular, Injection, Injection - Intramuscular, Liquid - Intramuscular, Topical, Cream, Cream - Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray

Warnings

Valtoco has six contraindications and should not be combined when suffering from any of the conditions indicated in the table below.Valtoco Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Obstructive Sleep Apnea (OSA)
Do Not Combine
Glaucoma
Do Not Combine
Myasthenia Gravis
Do Not Combine
Liver Failure
Do Not Combine
Respiratory Insufficiency
Do Not Combine
There are 20 known major drug interactions with Valtoco.
Common Valtoco Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Diazepam.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Diazepam.
Azelastine
Major
Diazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Diazepam.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Diazepam.
Valtoco Toxicity & Overdose RiskOverdosing on diazepam can lead to an intensification of the drug's effects, such as drowsiness, difficulty speaking, and weakened muscles. More severe symptoms include coma, loss of reflexes, slowed breathing and heart rate, and lack of oxygen. Taking diazepam with other drugs or alcohol can be fatal and should be avoided. Pregnant women should avoid taking diazepam altogether, and it is not recommended for breastfeeding mothers or children under 6 months of age. Elderly patients should take the smallest dose possible as they are more likely to have side effects. Patients with cirrhosis, hepatic encephal
image of a doctor in a lab doing drug, clinical research

Valtoco Novel Uses: Which Conditions Have a Clinical Trial Featuring Valtoco?

409 active clinical trials are currently investigating the potential of Valtoco to alleviate Anxiety Disorders, Generalized Anxiety Disorder and Stiff Man Syndrome.
Condition
Clinical Trials
Trial Phases
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Generalized Anxiety Disorder
205 Actively Recruiting
Phase 3, Not Applicable, Phase 2, Early Phase 1, Phase 4, Phase 1
Anxiety Disorders
54 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1
Lockjaw
1 Actively Recruiting
Phase 4
Stiff-Person Syndrome
5 Actively Recruiting
Phase 2, Not Applicable, Phase 1
Sedation
2 Actively Recruiting
Not Applicable, Phase 1
Motor Neuron Disease, Upper
0 Actively Recruiting
Athetosis
0 Actively Recruiting
Drug Resistant Epilepsy
1 Actively Recruiting
Not Applicable
Sedation therapy
0 Actively Recruiting
Status Epilepticus
0 Actively Recruiting
Seizures
0 Actively Recruiting
Muscle Tissue
0 Actively Recruiting
Anger Management Therapy
1 Actively Recruiting
Not Applicable

Patient Q&A Section about valtoco

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is Valtoco a narcotic?

"Valtoco nasal spray is a prescription medicine used to treat seizure clusters in adults and children who are at least 6 years old. Valtoco can be abused and can lead to dependence, so it is classified as a federal controlled substance (C-IV)."

Answered by AI

Can Valtoco be used for anxiety?

"Diazepam - FDA prescribing information, side effects and uses

Diazepam is used to treat anxiety disorders, alcohol withdrawal symptoms, or muscle spasms. It can also be used to relieve seizures."

Answered by AI

Is Valtoco a diazepam?

"Diazepam, which is the active ingredient in VALTOCO, has been used by medical professionals to treat epilepsy for over 50 years. For the last 20 years, patients and their carers have also used diazepam to rescue themselves from episodes of frequent seizure activity outside of a medical setting."

Answered by AI

What is Valtoco used for?

"The FDA has approved Valtoco, a new seizure medicine designed to treat periods of frequent seizures or cluster seizures that are distinct from the person's usual seizure pattern."

Answered by AI

Clinical Trials for Valtoco

Have you considered Valtoco clinical trials? We made a collection of clinical trials featuring Valtoco, we think they might fit your search criteria.
Have you considered Valtoco clinical trials? We made a collection of clinical trials featuring Valtoco, we think they might fit your search criteria.
Have you considered Valtoco clinical trials? We made a collection of clinical trials featuring Valtoco, we think they might fit your search criteria.
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