Valium
Athetosis, Lockjaw, Syndrome + 11 more
Treatment
20 Active Studies for Valium
Treatment for
Athetosis
What is Valium
Diazepam
The Generic name of this drug
Treatment Summary
Diazepam is a medication used to treat anxiety, insomnia, seizures, muscle spasms, and alcohol withdrawal. It works by increasing the activity of a chemical in the brain called gamma-aminobutyric acid. It was first approved in the 1930s and has since been used to treat many conditions. In 2015-2016, an auto-injectable form of diazepam was approved by the FDA for the rapid treatment of uncontrolled seizures. This new form of diazepam allows for faster and more effective drug absorption, making it a valuable addition to the treatments available for people with epilepsy.
Valium
is the brand name
Valium Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Valium
Diazepam
1963
289
Effectiveness
How Valium Affects Patients
Diazepam is a type of medication that has calming, sleep-inducing, muscle-relaxing, anti-convulsive, and memory-altering effects. It works by increasing the activity of a chemical in the brain called GABA, which helps to reduce anxiety and slow down the nervous system.
How Valium works in the body
Diazepam is a medication used to treat anxiety, seizures, and muscle spasms. It works by binding to receptors in the brain and spinal cord and increasing the activity of a chemical called GABA. This helps reduce the symptoms of anxiety, seizures, and muscle spasms.
When to interrupt dosage
The recommended dosage of Valium is predicated upon the diagnosed condition, such as Muscle Tissue, Seizures and Anger Management Therapy. The magnitude of dosage is contingent upon the administration technique specified in the table below.
Condition
Dosage
Administration
Drug Resistant Epilepsy
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Seizures
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Anger Management Therapy
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Muscle Tissue
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Athetosis
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Lockjaw
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Syndrome
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Motor Neuron Disease, Upper
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Sedation therapy
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Sedation
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Generalized Anxiety Disorder
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Anxiety Disorders
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Stiff-Person Syndrome
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Status Epilepticus
5.0 mg/mL, , 25.0 mg/mL, 10.0 mg/mL, 20.0 mg/mL, 5.0 mg, 10.0 mg, 2.0 mg, 1.0 mg/mL, 100.0 mg/mL, 50.0 mg/mL, 75.0 mg/mL, 15.0 mg/mL
, Oral, Solution - Oral, Solution, Gel, Gel - Rectal, Rectal, Tablet, Tablet - Oral, Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous, Injection, solution, Kit, Liquid - Intramuscular; Intravenous, Liquid, Emulsion, Emulsion - Intramuscular; Intravenous, Solution, concentrate, Solution, concentrate - Oral, Solution - Intramuscular; Intravenous, Injection - Intramuscular, Intramuscular, Injection, Liquid - Intramuscular, Cream - Topical, Cream, Topical, Injection - Intramuscular; Intravenous, Nasal, Spray - Nasal, Spray
Warnings
Valium Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Obstructive Sleep Apnea (OSA)
Do Not Combine
Glaucoma
Do Not Combine
Myasthenia Gravis
Do Not Combine
Liver Failure
Do Not Combine
Respiratory Insufficiency
Do Not Combine
There are 20 known major drug interactions with Valium.
Common Valium Drug Interactions
Drug Name
Risk Level
Description
Astemizole
Major
The metabolism of Astemizole can be decreased when combined with Diazepam.
Axitinib
Major
The metabolism of Axitinib can be decreased when combined with Diazepam.
Azelastine
Major
Diazepam may increase the central nervous system depressant (CNS depressant) activities of Azelastine.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Diazepam.
Copanlisib
Major
The metabolism of Copanlisib can be decreased when combined with Diazepam.
Valium Toxicity & Overdose Risk
Taking too much diazepam can cause the same effects as taking the drug as intended but to a more intense degree. These symptoms include difficulty walking, drowsiness, slurred speech, muscle weakness, very deep sleep, low blood pressure, slow heartbeat, and jerky eye movements. In extreme cases, it can lead to coma, lack of reflexes, respiratory depression, and not being able to breath. If taken with alcohol or other central nervous system depressants, it could be fatal. Women who are pregnant or breastfeeding should not take diazepam as it can be passed to the fetus or baby in the breastmilk.
Valium Novel Uses: Which Conditions Have a Clinical Trial Featuring Valium?
409 active trials are being conducted to assess the potential of Valium to alleviate Anxiety Disorders, Generalized Anxiety Disorder and Stiff Man Syndrome.
Condition
Clinical Trials
Trial Phases
Anxiety Disorders
56 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 3, Early Phase 1
Generalized Anxiety Disorder
183 Actively Recruiting
Not Applicable, Phase 2, Early Phase 1, Phase 4, Phase 1, Phase 3
Syndrome
4 Actively Recruiting
Phase 2, Phase 3, Not Applicable
Lockjaw
0 Actively Recruiting
Stiff-Person Syndrome
4 Actively Recruiting
Phase 2, Phase 1
Sedation
2 Actively Recruiting
Early Phase 1, Not Applicable
Motor Neuron Disease, Upper
0 Actively Recruiting
Athetosis
1 Actively Recruiting
Phase 3
Drug Resistant Epilepsy
1 Actively Recruiting
Not Applicable
Sedation therapy
0 Actively Recruiting
Status Epilepticus
0 Actively Recruiting
Seizures
0 Actively Recruiting
Muscle Tissue
0 Actively Recruiting
Anger Management Therapy
0 Actively Recruiting
Valium Reviews: What are patients saying about Valium?
5
Patient Review
1/26/2019
Valium for Sleep Disturbance with Extreme Anxiety
5
Patient Review
10/30/2021
Valium for Seizure with Loss of Normal Tone or Strength
5
Patient Review
5/10/2022
Valium for Psychosis caused by Sudden Alcohol Withdrawal
5
Patient Review
12/1/2016
Valium for Muscle Spasm
3.3
Patient Review
11/12/2017
Valium for Anxious
3
Patient Review
5/11/2018
Valium for Anxious
1.7
Patient Review
11/11/2017
Valium for Chronic Trouble Sleeping
1
Patient Review
6/21/2017
Valium for Muscle Spasm
1
Patient Review
2/14/2020
Valium for Chronic Trouble Sleeping
Patient Q&A Section about valium
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Does Valium make you sleepy?
"Diazepam (Valium) can make you feel sleepy and affect your concentration and focus, so you should avoid activities that require you to be alert, like driving or operating machinery, until you know how the medication affects you."
Answered by AI
Is Valium good for anxiety?
"Valium and similar benzodiazepines can help reduce the intensity of panic attacks, nervousness, and anxiety."
Answered by AI
What class of drugs is Valium?
"Benzodiazepines are a type of drug that has a sedating or calming effect. There are many drugs in this group, and some, such as diazepam (Valium), are prescribed as medication in the UK. They are typically prescribed for anxiety or sometimes for sleeping disorders."
Answered by AI
What does Valium do to you?
"Diazepam is a medication used to treat anxiety, alcohol withdrawal, seizures, and muscle spasms. It works by calming the brain and nerves."
Answered by AI