Uroxatral

Enlarged Prostate
Treatment
1 FDA approval
20 Active Studies for Uroxatral

What is Uroxatral

AlfuzosinThe Generic name of this drug
Treatment SummaryBenign prostatic hyperplasia (BPH) is a common condition in men over 60, where the prostate becomes enlarged and causes urinary issues such as urgency, frequency, and changes to urine flow. Alfuzosin is a medication used to treat BPH. It relaxes the muscles in the prostate and bladder neck, and was approved by the FDA in 2003. It is available from several pharmaceutical companies.
Uroxatralis the brand name
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Uroxatral Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Uroxatral
Alfuzosin
2004
38

Approved as Treatment by the FDA

Alfuzosin, otherwise known as Uroxatral, is approved by the FDA for 1 uses like Enlarged Prostate .
Enlarged Prostate

Effectiveness

How Uroxatral Affects PatientsAlfuzosin helps reduce symptoms of Benign Prostatic Hyperplasia (BPH) by relaxing the muscles in the bladder neck and prostate. It also helps by widening blood vessels, which can result in lower blood pressure and dizziness if combined with other medications. Therefore, caution should be taken if you are also taking nitrates or antihypertensives.
How Uroxatral works in the bodyAlfuzosin works by blocking alpha(1)-adrenoreceptors in the prostate and other parts of the lower urinary tract. This prevents the receptors from contracting, allowing the muscles to relax. This leads to an improvement in urine flow and a decrease in urinary symptoms in people with BPH.

When to interrupt dosage

The prescribed dosage of Uroxatral is contingent upon the diagnosed condition. The degree of dosage diverges, depending on the method of administration (e.g. Tablet, film coated, extended release or Tablet, extended release) featured in the table beneath.
Condition
Dosage
Administration
Enlarged Prostate
10.0 mg,
, Oral, Tablet, extended release, Tablet, extended release - Oral, Tablet, Tablet - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral

Warnings

Uroxatral has three contraindications and should not be consumed when suffering from the issues detailed in the following table.Uroxatral Contraindications
Condition
Risk Level
Notes
Pulse Frequency
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Alfuzosin may interact with Pulse Frequency
Liver
Do Not Combine
There are 20 known major drug interactions with Uroxatral.
Common Uroxatral Drug Interactions
Drug Name
Risk Level
Description
Hydroxyzine
Major
The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Hydroxyzine.
Mobocertinib
Major
The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Mobocertinib.
Ziprasidone
Major
The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Ziprasidone.
Abexinostat
Minor
The risk or severity of QTc prolongation can be increased when Alfuzosin is combined with Abexinostat.
Acebutolol
Minor
Alfuzosin may increase the hypotensive activities of Acebutolol.
Uroxatral Toxicity & Overdose RiskThe most toxic dose of alfuzosin that has been found in mice is 1950mg/kg for females and 2300mg/kg for males. Overdosing on alfuzosin can lead to low blood pressure, so the patient should lay down and may require medical assistance such as fluids or medication to restore pressure. Close monitoring of kidney function is also necessary, though dialysis may not be effective due to alfuzosin's high protein binding rate.
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Uroxatral Novel Uses: Which Conditions Have a Clinical Trial Featuring Uroxatral?

21 active trials are investigating the potential of Uroxatral to treat Enlarged Prostate conditions.
Condition
Clinical Trials
Trial Phases
Enlarged Prostate
21 Actively Recruiting
Not Applicable, Phase 4, Phase 2

Uroxatral Reviews: What are patients saying about Uroxatral?

5Patient Review
5/5/2013
Uroxatral for Enlarged Prostate
This drug has worked wonders for me. I've been taking it for BPH and ED and it's really helped with both issues. After just 10 days, my urination improved a lot--I went from having to go 3+ times per night to mostly just once. The bigger surprise was the effect on my ED. I'm noticeably larger in both the flaccid and aroused state. The only downside is that I have a slightly stuffy nose now.
5Patient Review
6/16/2012
Uroxatral for Enlarged Prostate with Urination Problems
Rapaflo helped me to urinate normally again, and Uroxathral has made sex more enjoyable by restoring ejaculate. I'm sticking with this treatment plan.
5Patient Review
9/29/2011
Uroxatral for Enlarged Prostate with Urination Problems
I urinate less frequently, which is great. However, I sometimes experience a weird sensation where my left lower leg feels hot, and then it goes back to normal. Not sure if this treatment is causing that or not, but if you're experiencing something similar, please let me know.
5Patient Review
1/17/2011
Uroxatral for Enlarged Prostate with Urination Problems
4.3Patient Review
9/14/2011
Uroxatral for Enlarged Prostate with Urination Problems
I've been using this medication for over a year and have found it to be effective. I only need to use the restroom every four to five hours, as opposed to every two hours. Additionally, there are no sexual side effects that I have experienced.
View All Reviews
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Patient Q&A Section about uroxatral

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does Uroxatral help erectile dysfunction?

"Uroxatral may help improve sexual function in males with both BPH and ED."

Answered by AI

What is Uroxatral used for?

"Alfuzosin is a medication used to treat benign prostatic hyperplasia (BPH) in men. This is a condition that causes the prostate to become enlarged. Alfuzosin helps relax the muscles around the prostate and bladder, making it easier to urinate and reducing the frequency of urination."

Answered by AI

What is the difference between Flomax and Uroxatral?

"Flomax (tamsulosin) is a good treatment for an enlarged prostate if medical treatment is needed, but it can reduce your sex drive and takes time to kick in."

Answered by AI

What are the side effects of Uroxatral?

"The text lists symptoms which may include dizziness, lightheadedness, headache, fatigue, tiredness, or cold symptoms such as a stuffy nose, sneezing, or sore throat."

Answered by AI

Clinical Trials for Uroxatral

Have you considered Uroxatral clinical trials? We made a collection of clinical trials featuring Uroxatral, we think they might fit your search criteria.
Have you considered Uroxatral clinical trials? We made a collection of clinical trials featuring Uroxatral, we think they might fit your search criteria.
Have you considered Uroxatral clinical trials? We made a collection of clinical trials featuring Uroxatral, we think they might fit your search criteria.
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