Triple Sulfa

Trachoma, Pink Eye, Conjunctivitis + 1 more

Treatment

5 Active Studies for Triple Sulfa

What is Triple Sulfa

Sulfacetamide

The Generic name of this drug

Treatment Summary

Sulfabenzamide is an antimicrobial medicine used in combination with two other drugs to treat bacterial infections in the vagina.

Blephamide

is the brand name

Triple Sulfa Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Blephamide

Sulfacetamide

1961

61

When to interrupt dosage

The suggested dosage of Triple Sulfa is contingent upon the diagnosed condition. The measure fluctuates depending on the method of delivery outlined in the table below.

Condition

Dosage

Administration

Trachoma

0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg

, Ointment - Ophthalmic, Ointment, Ophthalmic, Suspension - Topical, Topical, Suspension, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution, Solution - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Cream, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Rinse, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Suspension - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical

Pink Eye

0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg

, Ointment - Ophthalmic, Ointment, Ophthalmic, Suspension - Topical, Topical, Suspension, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution, Solution - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Cream, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Rinse, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Suspension - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical

Conjunctivitis

0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg

, Ointment - Ophthalmic, Ointment, Ophthalmic, Suspension - Topical, Topical, Suspension, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution, Solution - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Cream, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Rinse, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Suspension - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical

Acne Vulgaris

0.1 mg/mg, , 100.0 mg/mL, 0.098 mg/mg, 300.0 mg/mL, 80.0 mg/mL, 0.009 mg/mg, 0.9 mg/mL, 0.09 mg/mg, 1000.0 mg/mL, 10.0 mg/mL, 90.0 mg/mL, 10.0 %, 100.0 mg, 0.01 mg/mg, 0.095 mg/mg, 150.0 mg/mL, 98.0 mg/mL, 0.0286 mg/mg, 0.28 mg/mg, 0.08 mg/mg, 0.05 mg/mg, 0.15 mg/mg, 0.0098 mg/mg

, Ointment - Ophthalmic, Ointment, Ophthalmic, Suspension - Topical, Topical, Suspension, Cream - Topical, Lotion, Lotion - Topical, Aerosol, foam, Aerosol, foam - Topical, Solution, Solution - Topical, Solution / drops, Solution / drops - Ophthalmic, Solution - Ophthalmic, Liquid, Swab, Swab - Topical, Liquid - Topical, Cloth, Cloth - Topical, Gel, Rinse - Topical, Gel - Topical, Cream, Kit, Suspension / drops - Ophthalmic, Suspension / drops, Soap, Soap - Topical, Liquid - Ophthalmic, Rinse, Shampoo, Shampoo - Topical, Emulsion, Emulsion - Topical, Suspension - Ophthalmic, Ointment - Ophthalmic; Topical, Ophthalmic; Topical, Kit - Topical, Vaginal, Cream - Vaginal, Lotion / shampoo, Lotion / shampoo - Topical

Warnings

Triple Sulfa Contraindications

Condition

Risk Level

Notes

Chronic Kidney Disease (CKD)

Do Not Combine

There are 17 known major drug interactions with Triple Sulfa.

Common Triple Sulfa Drug Interactions

Drug Name

Risk Level

Description

Vibrio cholerae CVD 103-HgR strain live antigen

Major

The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Sulfacetamide.

Benzylpenicillin

Moderate

Sulfacetamide may decrease the excretion rate of Benzylpenicillin which could result in a higher serum level.

Estetrol

Moderate

The therapeutic efficacy of Estetrol can be decreased when used in combination with Sulfacetamide.

Insulin argine

Moderate

The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin argine.

Insulin aspart

Moderate

The risk or severity of hypoglycemia can be increased when Sulfacetamide is combined with Insulin aspart.

Triple Sulfa Novel Uses: Which Conditions Have a Clinical Trial Featuring Triple Sulfa?

Currently, there are 0 active clinical trials investigating the potential of Triple Sulfa in treating various undetermined conditions.

Condition

Clinical Trials

Trial Phases

Trachoma

2 Actively Recruiting

Phase 4, Not Applicable

Acne Vulgaris

3 Actively Recruiting

Phase 1, Phase 2, Early Phase 1, Phase 4

Pink Eye

0 Actively Recruiting

Conjunctivitis

0 Actively Recruiting

Patient Q&A Section about triple sulfa

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What are the names of sulfa antibiotics?

"Gantrisin, Bactrim, and Septra are all sulfonamides, a class of antibiotics. Sulfadiazine and Azulfidine are also sulfonamides. Zonegran is an anticonvulsant."

Answered by AI

What does triple sulfa Treat?

"Trisulfapyrimidine, also known as triple sulfa, is a combination of sulfadiazine, sulfamerazine, and sulfamethazine. It is commonly used to treat vaginal infections, but can also be used in combination with other drugs to treat conditions ranging from skin burns to malaria and pneumonia in HIV/AIDS patients."

Answered by AI

Is triple sulfa an antibiotic?

"Triple sulfa is an antibacterial medication used to fight bacteria in the body and to treat vaginal infections caused by the bacteria Gardnerella vaginalis."

Answered by AI

What class is triple sulfa?

"Three sulfonamides, sulfadiazine, sulfamerazine, and sulfamethazine, work together to create a triple sulfa that is active against T. gondii. This combination is more effective than pyrimethamine alone."

Answered by AI

Clinical Trials for Triple Sulfa

Image of University of North Carolina in Chapel Hill, United States.

BLTR vs B-RAP for Trichiasis

18+
All Sexes
Chapel Hill, NC

The primary objective of this randomized clinical trial is to determine whether repeat trichiasis surgery performed with Bevel-Rotate Advancement Procedure (B-RAP) improves surgical success compared to Bilamellar Tarsal Rotation (BLTR) among a group of 8-10 TT surgeons in Tanzania. The study aims to enroll 1,000 individuals with PTT. The primary outcome is repeat PTT within one year after surgery. Additionally, the study will assess eyelid contour abnormalities and how they change over a two-year period as well as patient reported outcomes. If this project is successful in improving surgical outcomes, it could change the approach to treating PTT globally. Individuals with trichiasis have a significantly reduced quality of life; correcting their trichiasis long-term has the potential to improve their quality of life and their family members' quality of life considerably.

Waitlist Available
Has No Placebo

University of North Carolina

Emily Gower, PhD

Image of Medical University of South Carolina in Charleston, United States.

Isotretinoin vs Tetracycline for Acne

Any Age
All Sexes
Charleston, SC

In the effort to find better treatments for Moderate Acne, which often relies on long-term antibiotic use, researchers are exploring alternative options. While Isotretinoin, a Vitamin A derivative, is highly effective for severe acne, its side effects limit its use for milder cases. A recent study from our institution investigated a new approach: weekly Isotretinoin dosing. The results were promising, with acne improvement and no major side effects. This suggests that weekly Isotretinoin could be a successful alternative for moderate acne in both males and females. To validate these findings, investigators propose a randomized controlled trial comparing weekly Isotretinoin to daily Doxycycline over four months. This study could confirm the safety and effectiveness of weekly Isotretinoin, as well as shed light on patient satisfaction, and long-term results compared to standard antibiotics. This research may offer a breakthrough in treating moderate acne while addressing concerns about antibiotic overuse.

Phase < 1
Recruiting

Medical University of South Carolina

Alex Richmond, MD, MSCR

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