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What is Butalbital And Acetaminophen
ButalbitalThe Generic name of this drug
Treatment SummaryAcetaminophen, also known as Tylenol, is a widely used pain reliever and fever reducer. It comes in many forms, including syrup, tablets, injections, and suppositories. Acetaminophen is often combined with other drugs and can be found in over 600 OTC medications. Care must be taken when using or prescribing acetaminophen, as incorrect use can lead to serious overdose and liver failure. It is important to follow current dosing guidelines from the World Health Organization and manufacturers when taking or prescribing this drug.
Fiorinalis the brand name
Butalbital And Acetaminophen Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Fiorinal
Butalbital
1976
283
Approved as Treatment by the FDA
Butalbital, also known as Fiorinal, is approved by the FDA for 2 uses such as Inadequate analgesia and Tension Headache .Inadequate analgesia
Used to treat Inadequate analgesia in combination with Acetaminophen
Tension Headache
Used to treat Tension Headache in combination with Acetaminophen
Effectiveness
How Butalbital And Acetaminophen Affects PatientsAcetaminophen has been shown to be effective in reducing fever and providing pain relief. Unlike aspirin, it won’t cause problems with uric acid levels or affect acid-base balance. Additionally, acetaminophen doesn’t interfere with the body’s ability to clot, and allergic reactions are very rare.
How Butalbital And Acetaminophen works in the bodyAcetaminophen works to reduce pain by blocking the cyclooxygenase (COX) pathways, which are involved in producing pain signals. Acetaminophen does this by inhibiting two types of COX enzymes, known as COX-1 and COX-2. It does not block these enzymes in other parts of the body, so it does not have anti-inflammatory effects. Acetaminophen also appears to block a third type of COX enzyme, known as COX-3. It is also believed to reduce fever by acting on heat-regulating centers in the brain. However, the exact mechanism
When to interrupt dosage
The proposed dose of Butalbital And Acetaminophen is dependent upon the recognized situation, such as Pain, Spasm and Inflammation. The amount of dosage is contingent upon the mode of administration enumerated in the table below.Condition
Dosage
Administration
Inadequate analgesia
, 50.0 mg, 5.0 mg/mL, 25.0 mg, 25.0 mg/mg
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Tablet, coated - Oral, Tablet, coated
Tension Headache
, 50.0 mg, 5.0 mg/mL, 25.0 mg, 25.0 mg/mg
, Oral, Capsule, Capsule - Oral, Tablet, Tablet - Oral, Syrup, Syrup - Oral, Tablet, coated - Oral, Tablet, coated
Warnings
Butalbital And Acetaminophen has three prohibitions for use. It should not be utilized if you experience any of the circumstances outlined in the following table.Butalbital And Acetaminophen ContraindicationsCondition
Risk Level
Notes
Porphyria
Do Not Combine
Post-Tonsillectomy
Do Not Combine
Porphyria
Do Not Combine
post-adenoidectomy
Do Not Combine
Common Butalbital And Acetaminophen Drug Interactions
Drug Name
Risk Level
Description
Abemaciclib
Major
The metabolism of Abemaciclib can be increased when combined with Butalbital.
Acalabrutinib
Major
The metabolism of Acalabrutinib can be increased when combined with Butalbital.
Alectinib
Major
The metabolism of Alectinib can be increased when combined with Butalbital.
Alpelisib
Major
The metabolism of Alpelisib can be increased when combined with Butalbital.
Amiodarone
Major
The metabolism of Amiodarone can be increased when combined with Butalbital.
Butalbital And Acetaminophen Toxicity & Overdose RiskLD50 of acetaminophen is 338 mg/kg for mice and 1944 mg/kg for rats. An overdose of acetaminophen can cause kidney damage, low blood sugar, low platelet levels, and liver damage that can lead to death or the need for a liver transplant. Long-term use of acetaminophen has been found to increase the risk of leukemia in female rats, but not in male rats or mice. Acetaminophen has not been found to be mutagenic, but it can cause chromosomal changes at high doses. Acetaminophen has not been shown to affect fertility or cause any major birth defects
Butalbital And Acetaminophen Novel Uses: Which Conditions Have a Clinical Trial Featuring Butalbital And Acetaminophen?
698 active trials are investigating the use of Butalbital And Acetaminophen in relieving Chronic Pain, Rheumatoid Arthritis and Allergy.Condition
Clinical Trials
Trial Phases
Inadequate analgesia
0 Actively Recruiting
Tension Headache
0 Actively Recruiting
Butalbital And Acetaminophen Reviews: What are patients saying about Butalbital And Acetaminophen?
5Patient Review
1/24/2018 I originally started taking this medication for migraines and it worked great! However, the last few times I've taken it I've broken out in hives. The first time it happened I thought I'd been bitten by mosquitoes (stupid, I know). But recently it happened again and now I'm covered in hives! Has anyone else experienced this side effect?
5Patient Review
6/26/2021 I was in the hospital recently and had no idea this drug existed until the doctor offered it to me for my headaches. I found relief with Fioricet and am very satisfied with how it has improved my quality of life!
5Patient Review
1/19/2022 This medication has been a lifesaver. When I feel like my head is going to explode, I take one of these and the pain disappears within minutes.
5Patient Review
8/27/2020 I've been dealing with migraines for two decades and this treatment has really helped me manage them. When I start to feel a migraine coming on, I take these and it helps prevent them from getting too out of control.
5Patient Review
5/4/2018 I have had basilar migraines since I was 13, and they come in waves throughout the day. They are extremely sensitive to light and sound, and this medication made them worse.
5Patient Review
9/26/20175Patient Review
9/6/2020 I've been using this medication for 15 years, ever since I was in a car accident. It's really helped me deal with my migraines. And I'm glad it works for me, because I've had some unhelpful doctors tell me it's useless.
5Patient Review
1/18/2019 Unfortunately, this drug made my headache worse instead of better. I won't be taking it again.
5Patient Review
9/26/20175Patient Review
5/4/2018 I've been dealing with migraines since I was a teenager, and they usually come in waves throughout the day (I get about seven to nine of them). They're light-sensitive and sound-sensitive, which makes this medication terrible for me. After taking it, I had an even worse migraine within 25 minutes. It made me nauseous and gave me suicidal thoughts, depression, and anxiety. I'll try anything to treat my migraines at this point, but not this medication again.
5Patient Review
1/24/2018 Though it's effective for migraines, I have recently developed a reaction to the medication in the form of hives. Has anyone else had this issue?
5Patient Review
1/18/2019 This drug didn't help me at all. In fact, it made my headache worse. I won't be taking it again.
5Patient Review
9/6/2020 I've been taking this medication for 15 years, ever since I was in a car accident. It's helped me immensely; I couldn't imagine living without it.
5Patient Review
8/27/2020 I've been managing migraines for about two decades now, and this treatment has made a world of difference. When I can tell one is coming on, I take these and it helps immensely.
5Patient Review
6/26/2021 I had no idea that this medication existed until I was recently hospitalized. It's been an absolute game-changer for my headaches; nothing else has worked as well, not even Dilaudid or methadone. This has drastically improved my quality of life and I couldn't be more pleased.
5Patient Review
1/19/2022 This medication is really effective. When I started taking it, I was sceptical that it would help me. But little by little, I saw improvements. And now, whenever I have a headache, this is the first thing I reach for.
4.3Patient Review
1/14/2020 This patient says this medication does a great job at treating her tension headaches. She claims it has even stopped migraines that would last for days, and without any nausea!
4.3Patient Review
10/16/20174.3Patient Review
10/16/20174.3Patient Review
1/14/2020 My patient says this treatment works very well for her tension headaches. She's found that it prevents migraines from lasting for days, and without any nausea!
3.7Patient Review
4/28/2021 I've been on this medication for almost three months now, and it's been doing its job well. I only had to take one pill today because my nerve blockage shot has worn out, but even that was enough to help me. I'm not a fan of pills in general, but these seem to work well. My doctor wants me to up my dose to two pills a day though, because recently I had an incident where I was in a lot of pain and felt like my head was going to explode.
3.7Patient Review
3/18/2022 This medication is effective at treating my headaches, however I do not like the fact that it contains caffeine. The caffeine makes me feel shaky, even when taken with food.
3.7Patient Review
3/18/2022 This alleviated my headaches caused by TBI, but I unfortunately experienced some negative side effects like shaking.
3.7Patient Review
4/28/2021 I've been on this medication for about three months now, and it's helped a lot. I only took one pill today because my nerve blockage shot has worn out, but even so the pill worked well. My doctor wants to up my dose to two pills a day though because I had an incident recently where I felt like my head was going to explode from the pain.
3.3Patient Review
11/16/2019 This medication really helped me get over the flu quickly.
3.3Patient Review
11/16/2019 This medication helped clear up my flu symptoms quickly.
3Patient Review
5/11/2020 If I take this medication as soon as I feel a headache coming on, it usually prevents it from turning into a full-blown migraine. When I first started taking it, one tablet was enough. Nowadays, I find that I need two tablets to get the same effect.
3Patient Review
5/11/2020 If I take this medication as soon as a headache begins, it usually prevents it from developing into a migraine. I started taking this drug years ago in tablet form, but now find that I need two tablets to get the same level of relief.
2.3Patient Review
11/8/2020 I unfortunately didn't experience any reduction in headaches after using this medication.
2.3Patient Review
11/8/2020 I didn't find this effective in reducing the frequency or intensity of my headaches.
2Patient Review
10/15/2021 Unfortunately, this medication did not touch my headaches at all.
2Patient Review
7/22/2018 If I take 2 capsules when a visual aura is just beginning, I usually have very little, if any, pain.
2Patient Review
10/15/2021 This medication did not provide relief for my headaches.
2Patient Review
7/22/2018 If I take 2 capsules when a visual aura is just beginning, I usually have very little, if any, pain.
Patient Q&A Section about butalbital and acetaminophen
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is butalbital A acetaminophen?
"This medicine is a white, oblong, tablet imprinted with "LL 722"."
Answered by AI
Can I take Tylenol with butalbital?
"This medicine contains a barbiturate or acetaminophen. Taking it with alcohol or other CNS depressants may cause an overdose. The butalbital in this medicine will make the effects of alcohol and other CNS depressants worse."
Answered by AI
What is butalbital acetaminophen used for?
"Butalbital and acetaminophen is a pain reliever and relaxant that is used to treat tension headaches. Butalbital belongs to a class of drugs called barbiturates, which work by depressing the central nervous system."
Answered by AI
How long after taking Tylenol can I take butalbital?
"Do not take anything else that contains caffeine or acetaminophen for at least 4 hours after taking Fioricet so you don't overdose on these ingredients."
Answered by AI